PBYI vs. RIGL
PBYI (Puma Biotechnology, Inc.) and RIGL (Rigel Pharmaceuticals, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, PBYI returned -12.52%/yr vs 4.42%/yr for RIGL. At a 0.32 correlation, their price movements are largely independent.
Performance
PBYI vs. RIGL - Performance Comparison
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Returns By Period
In the year-to-date period, PBYI achieves a 35.13% return, which is significantly higher than RIGL's -16.86% return. Over the past 10 years, PBYI has underperformed RIGL with an annualized return of -12.52%, while RIGL has yielded a comparatively higher 4.42% annualized return.
PBYI
- 1D
- 4.96%
- 1M
- 13.56%
- YTD
- 35.13%
- 6M
- 36.04%
- 1Y
- 140.00%
- 3Y*
- 31.32%
- 5Y*
- -4.08%
- 10Y*
- -12.52%
RIGL
- 1D
- -0.34%
- 1M
- 22.75%
- YTD
- -16.86%
- 6M
- -18.96%
- 1Y
- 88.96%
- 3Y*
- 28.46%
- 5Y*
- -3.70%
- 10Y*
- 4.42%
PBYI vs. RIGL - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
PBYI Puma Biotechnology, Inc. | 35.13% | 95.08% | -29.56% | 2.36% | 39.14% | -70.37% | 17.26% | -57.00% | -79.41% | 221.99% |
RIGL Rigel Pharmaceuticals, Inc. | -16.86% | 154.64% | 16.00% | -3.33% | -43.40% | -24.29% | 63.55% | -6.96% | -40.72% | 63.03% |
Correlation
The correlation between PBYI and RIGL is 0.25, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.25 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.23 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.29 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.33 |
Correlation (All Time) Calculated using the full available price history since Apr 24, 2012 | 0.32 |
Fundamentals
PBYI:
$408.79M
RIGL:
$701.02M
PBYI:
$0.48
RIGL:
$19.21
PBYI:
16.83
RIGL:
1.85
PBYI:
0.02
RIGL:
0.00
PBYI:
1.80
RIGL:
2.25
PBYI:
3.18
RIGL:
1.75
PBYI:
$227.21M
RIGL:
$299.77M
PBYI:
$169.14M
RIGL:
$279.95M
PBYI:
$46.97M
RIGL:
$125.80M
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Return for Risk
PBYI vs. RIGL — Risk / Return Rank
PBYI
RIGL
PBYI vs. RIGL - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Puma Biotechnology, Inc. (PBYI) and Rigel Pharmaceuticals, Inc. (RIGL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PBYI | RIGL | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.76 | ||
| Sortino ratioReturn per unit of downside risk | +0.39 | ||
| Omega ratioGain probability vs. loss probability | 1.42 | 1.27 | +0.14 |
| Calmar ratioReturn relative to maximum drawdown | 5.46 | 1.79 | +3.68 |
| Martin ratioReturn relative to average drawdown | 12.67 | 3.09 | +9.58 |
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Drawdowns
PBYI vs. RIGL - Drawdown Comparison
The maximum PBYI drawdown since its inception was -99.40%, roughly equal to the maximum RIGL drawdown of -99.37%. Use the drawdown chart below to compare losses from any high point for PBYI and RIGL.
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Drawdown Indicators
| PBYI | RIGL | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.40% | -99.37% | -0.03% |
Max Drawdown (1Y)Largest decline over 1 year | -25.78% | -50.08% | +24.30% |
Max Drawdown (3Y)Largest decline over 3 years | -69.59% | -57.00% | -12.59% |
Max Drawdown (5Y)Largest decline over 5 years | -82.97% | -85.24% | +2.27% |
Max Drawdown (10Y)Largest decline over 10 years | -98.76% | -86.40% | -12.36% |
Current DrawdownCurrent decline from peak | -97.08% | -96.67% | -0.41% |
Average DrawdownAverage peak-to-trough decline | -74.48% | -90.91% | +16.43% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 11.10% | 28.92% | -17.82% |
Volatility
PBYI vs. RIGL - Volatility Comparison
Puma Biotechnology, Inc. (PBYI) and Rigel Pharmaceuticals, Inc. (RIGL) have volatilities of 10.58% and 10.68%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PBYI | RIGL | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 10.58% | 10.68% | -0.10% |
Volatility (6M)Calculated over the trailing 6-month period | 41.88% | 37.45% | +4.43% |
Volatility (1Y)Calculated over the trailing 1-year period | 69.36% | 70.06% | -0.70% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 75.89% | 85.53% | -9.64% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 80.60% | 82.83% | -2.23% |
Dividends
PBYI vs. RIGL - Dividend Comparison
Neither PBYI nor RIGL has paid dividends to shareholders.
Financials
PBYI vs. RIGL - Financials Comparison
This section allows you to compare key financial metrics between Puma Biotechnology, Inc. and Rigel Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
PBYI vs. RIGL - Profitability Comparison
PBYI - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Puma Biotechnology, Inc. reported a gross profit of 34.40M and revenue of 44.80M. Therefore, the gross margin over that period was 76.8%.
RIGL - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Rigel Pharmaceuticals, Inc. reported a gross profit of 54.21M and revenue of 58.82M. Therefore, the gross margin over that period was 92.2%.
PBYI - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Puma Biotechnology, Inc. reported an operating income of -3.83M and revenue of 44.80M, resulting in an operating margin of -8.5%.
RIGL - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Rigel Pharmaceuticals, Inc. reported an operating income of 11.89M and revenue of 58.82M, resulting in an operating margin of 20.2%.
PBYI - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Puma Biotechnology, Inc. reported a net income of -3.80M and revenue of 44.80M, resulting in a net margin of -8.5%.
RIGL - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Rigel Pharmaceuticals, Inc. reported a net income of 8.65M and revenue of 58.82M, resulting in a net margin of 14.7%.
Frequently Asked Questions
PBYI and RIGL have a correlation of 0.25, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
RIGL has higher volatility (10.68%) compared to PBYI (10.58%). In terms of maximum drawdown, PBYI dropped -99.40% vs RIGL's -99.37%.
PBYI currently has the higher Sharpe Ratio (2.03 vs 1.28), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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