ONC vs. BIIB
Compare and contrast key facts about BeOne Medicines Ltd (ONC) and Biogen Inc. (BIIB).
Performance
ONC vs. BIIB - Performance Comparison
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ONC vs. BIIB - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
ONC BeOne Medicines Ltd | -2.25% | 64.48% | 2.41% | -18.00% | -18.82% | 4.85% | 55.88% | 18.18% | 43.53% | 221.87% |
BIIB Biogen Inc. | 4.17% | 15.09% | -40.91% | -6.55% | 15.42% | -2.02% | -17.48% | -1.39% | -5.54% | 12.34% |
Fundamentals
ONC:
$33.69B
BIIB:
$26.89B
ONC:
$2.53
BIIB:
$8.82
ONC:
117.58
BIIB:
20.77
ONC:
6.31
BIIB:
2.74
ONC:
7.73
BIIB:
1.47
ONC:
$5.34B
BIIB:
$9.81B
ONC:
$4.67B
BIIB:
$6.91B
ONC:
$515.55M
BIIB:
$3.10B
Returns By Period
In the year-to-date period, ONC achieves a -2.25% return, which is significantly lower than BIIB's 4.17% return. Over the past 10 years, ONC has outperformed BIIB with an annualized return of 26.10%, while BIIB has yielded a comparatively lower -3.45% annualized return.
ONC
- 1D
- 4.54%
- 1M
- -6.32%
- YTD
- -2.25%
- 6M
- -12.84%
- 1Y
- 9.11%
- 3Y*
- 11.28%
- 5Y*
- -2.80%
- 10Y*
- 26.10%
BIIB
- 1D
- -2.26%
- 1M
- -4.43%
- YTD
- 4.17%
- 6M
- 30.88%
- 1Y
- 33.97%
- 3Y*
- -12.96%
- 5Y*
- -8.04%
- 10Y*
- -3.45%
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Return for Risk
ONC vs. BIIB — Risk / Return Rank
ONC
BIIB
ONC vs. BIIB - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for BeOne Medicines Ltd (ONC) and Biogen Inc. (BIIB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| ONC | BIIB | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 0.20 | 0.99 | -0.79 |
Sortino ratioReturn per unit of downside risk | 0.63 | 1.63 | -1.01 |
Omega ratioGain probability vs. loss probability | 1.08 | 1.19 | -0.11 |
Calmar ratioReturn relative to maximum drawdown | 0.41 | 1.90 | -1.49 |
Martin ratioReturn relative to average drawdown | 0.93 | 4.80 | -3.87 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| ONC | BIIB | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.20 | 0.99 | -0.79 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.05 | -0.21 | +0.16 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | 0.47 | -0.08 | +0.55 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.46 | 0.22 | +0.24 |
Correlation
The correlation between ONC and BIIB is 0.25, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.
Dividends
ONC vs. BIIB - Dividend Comparison
Neither ONC nor BIIB has paid dividends to shareholders.
Drawdowns
ONC vs. BIIB - Drawdown Comparison
The maximum ONC drawdown since its inception was -69.96%, smaller than the maximum BIIB drawdown of -89.98%. Use the drawdown chart below to compare losses from any high point for ONC and BIIB.
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Drawdown Indicators
| ONC | BIIB | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -69.96% | -89.98% | +20.02% |
Max Drawdown (1Y)Largest decline over 1 year | -27.22% | -14.13% | -13.09% |
Max Drawdown (5Y)Largest decline over 5 years | -69.96% | -72.66% | +2.70% |
Max Drawdown (10Y)Largest decline over 10 years | -69.96% | -72.66% | +2.70% |
Current DrawdownCurrent decline from peak | -26.34% | -61.48% | +35.14% |
Average DrawdownAverage peak-to-trough decline | -29.71% | -36.48% | +6.77% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 11.90% | 6.78% | +5.12% |
Volatility
ONC vs. BIIB - Volatility Comparison
BeOne Medicines Ltd (ONC) has a higher volatility of 11.37% compared to Biogen Inc. (BIIB) at 8.91%. This indicates that ONC's price experiences larger fluctuations and is considered to be riskier than BIIB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ONC | BIIB | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 11.37% | 8.91% | +2.46% |
Volatility (6M)Calculated over the trailing 6-month period | 27.77% | 24.16% | +3.61% |
Volatility (1Y)Calculated over the trailing 1-year period | 46.54% | 34.48% | +12.06% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 56.65% | 38.11% | +18.54% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 55.89% | 41.40% | +14.49% |
Financials
ONC vs. BIIB - Financials Comparison
This section allows you to compare key financial metrics between BeOne Medicines Ltd and Biogen Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
ONC vs. BIIB - Profitability Comparison
ONC - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, BeOne Medicines Ltd reported a gross profit of 1.36B and revenue of 1.50B. Therefore, the gross margin over that period was 90.5%.
BIIB - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Biogen Inc. reported a gross profit of 1.78B and revenue of 2.28B. Therefore, the gross margin over that period was 78.2%.
ONC - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, BeOne Medicines Ltd reported an operating income of 185.04M and revenue of 1.50B, resulting in an operating margin of 12.4%.
BIIB - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Biogen Inc. reported an operating income of -57.00M and revenue of 2.28B, resulting in an operating margin of -2.5%.
ONC - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, BeOne Medicines Ltd reported a net income of 66.50M and revenue of 1.50B, resulting in a net margin of 4.4%.
BIIB - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Biogen Inc. reported a net income of -48.41M and revenue of 2.28B, resulting in a net margin of -2.1%.