PortfoliosLab logoPortfoliosLab logo
BIIB vs. MRK
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

BIIB vs. MRK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Biogen Inc. (BIIB) and Merck & Co., Inc. (MRK). The values are adjusted to include any dividend payments, if applicable.

Loading charts...

Returns By Period

In the year-to-date period, BIIB achieves a 7.30% return, which is significantly lower than MRK's 10.68% return. Over the past 10 years, BIIB has underperformed MRK with an annualized return of -4.21%, while MRK has yielded a comparatively higher 11.28% annualized return.


BIIB

1D
-1.77%
1M
0.95%
YTD
7.30%
6M
4.80%
1Y
43.99%
3Y*
-14.32%
5Y*
-7.08%
10Y*
-4.21%

MRK

1D
0.42%
1M
3.11%
YTD
10.68%
6M
16.30%
1Y
57.18%
3Y*
4.06%
5Y*
12.86%
10Y*
11.28%
*Multi-year figures are annualized to reflect compound growth (CAGR)

BIIB vs. MRK - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
BIIB
Biogen Inc.
7.30%15.09%-40.91%-6.55%15.42%-2.02%-17.48%-1.39%-5.54%12.34%
MRK
Merck & Co., Inc.
10.68%9.79%-6.26%1.01%49.42%1.75%-7.20%22.27%39.95%-1.49%

Correlation

The correlation between BIIB and MRK is 0.46, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.46

Correlation (3Y)
Calculated over the trailing 3-year period

0.36

Correlation (5Y)
Calculated over the trailing 5-year period

0.35

Correlation (10Y)
Calculated over the trailing 10-year period

0.36

Correlation (All Time)
Calculated using the full available price history since Sep 18, 1991

0.28

The correlation between BIIB and MRK shifts across timeframes, from 0.28 (all time) to 0.46 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

EPS

BIIB:

$12.48

MRK:

$3.58

PE Ratio

BIIB:

15.12

MRK:

32.26

PEG Ratio

BIIB:

1.05

MRK:

0.03

PS Ratio

BIIB:

2.11

MRK:

4.40

Total Revenue (TTM)

BIIB:

$9.86B

MRK:

$65.59B

Gross Profit (TTM)

BIIB:

$5.06B

MRK:

$49.79B

EBITDA (TTM)

BIIB:

$2.24B

MRK:

$22.69B

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Return for Risk

BIIB vs. MRK — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BIIB
BIIB Risk / Return Rank: 7878
Overall Rank
BIIB Sharpe Ratio Rank: 7878
Sharpe Ratio Rank
BIIB Sortino Ratio Rank: 7676
Sortino Ratio Rank
BIIB Omega Ratio Rank: 7171
Omega Ratio Rank
BIIB Calmar Ratio Rank: 8383
Calmar Ratio Rank
BIIB Martin Ratio Rank: 8383
Martin Ratio Rank

MRK
MRK Risk / Return Rank: 8989
Overall Rank
MRK Sharpe Ratio Rank: 8989
Sharpe Ratio Rank
MRK Sortino Ratio Rank: 8888
Sortino Ratio Rank
MRK Omega Ratio Rank: 8585
Omega Ratio Rank
MRK Calmar Ratio Rank: 9191
Calmar Ratio Rank
MRK Martin Ratio Rank: 9090
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BIIB vs. MRK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Biogen Inc. (BIIB) and Merck & Co., Inc. (MRK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


BIIBMRKDifference

Sharpe ratio

Return per unit of total volatility

1.34

2.14

-0.80

Sortino ratio

Return per unit of downside risk

2.08

3.06

-0.99

Omega ratio

Gain probability vs. loss probability

1.24

1.37

-0.13

Calmar ratio

Return relative to maximum drawdown

3.17

4.93

-1.75

Martin ratio

Return relative to average drawdown

7.80

12.44

-4.64

BIIB vs. MRK - Sharpe Ratio Comparison

The current BIIB Sharpe Ratio is 1.34, which is lower than the MRK Sharpe Ratio of 2.14. The chart below compares the historical Sharpe Ratios of BIIB and MRK, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


Loading charts...

Sharpe Ratios by Period


BIIBMRKDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.34

2.14

-0.80

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

-0.19

0.55

-0.73

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

-0.10

0.49

-0.60

Sharpe Ratio (All Time)

Calculated using the full available price history

0.22

0.48

-0.26

Drawdowns

BIIB vs. MRK - Drawdown Comparison

The maximum BIIB drawdown since its inception was -89.98%, which is greater than MRK's maximum drawdown of -68.61%. Use the drawdown chart below to compare losses from any high point for BIIB and MRK.


Loading charts...

Drawdown Indicators


BIIBMRKDifference

Max Drawdown

Largest peak-to-trough decline

-89.98%

-68.61%

-21.37%

Max Drawdown (1Y)

Largest decline over 1 year

-14.34%

-11.37%

-2.97%

Max Drawdown (3Y)

Largest decline over 3 years

-63.82%

-43.44%

-20.38%

Max Drawdown (5Y)

Largest decline over 5 years

-72.66%

-43.44%

-29.22%

Max Drawdown (10Y)

Largest decline over 10 years

-72.66%

-43.44%

-29.22%

Current Drawdown

Current decline from peak

-60.33%

-7.74%

-52.59%

Average Drawdown

Average peak-to-trough decline

-36.60%

-18.85%

-17.75%

Ulcer Index

Depth and duration of drawdowns from previous peaks

5.83%

4.50%

+1.33%

Volatility

BIIB vs. MRK - Volatility Comparison

Biogen Inc. (BIIB) has a higher volatility of 9.17% compared to Merck & Co., Inc. (MRK) at 8.19%. This indicates that BIIB's price experiences larger fluctuations and is considered to be riskier than MRK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


Loading charts...

Volatility by Period


BIIBMRKDifference

Volatility (1M)

Calculated over the trailing 1-month period

9.17%

8.19%

+0.98%

Volatility (6M)

Calculated over the trailing 6-month period

24.01%

17.85%

+6.16%

Volatility (1Y)

Calculated over the trailing 1-year period

33.03%

26.92%

+6.11%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

38.41%

23.64%

+14.77%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

41.47%

22.91%

+18.56%

Dividends

BIIB vs. MRK - Dividend Comparison

BIIB has not paid dividends to shareholders, while MRK's dividend yield for the trailing twelve months is around 2.87%.


PositionTTM20252024202320222021202020192018201720162015
BIIB
Biogen Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
MRK
Merck & Co., Inc.
2.87%3.12%3.14%2.72%2.52%3.41%3.03%2.48%2.60%3.36%3.14%3.43%

Financials

BIIB vs. MRK - Financials Comparison

This section allows you to compare key financial metrics between Biogen Inc. and Merck & Co., Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


5.00B10.00B15.00B20222023202420252026
2.48B
16.29B
(BIIB) Total Revenue
(MRK) Total Revenue
Values in USD except per share items

BIIB vs. MRK - Profitability Comparison

The chart below illustrates the profitability comparison between Biogen Inc. and Merck & Co., Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

0.0%20.0%40.0%60.0%80.0%202220232024202520260
81.9%
Portfolio components
BIIB - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Biogen Inc. reported a gross profit of 0.00 and revenue of 2.48B. Therefore, the gross margin over that period was 0.0%.

MRK - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Merck & Co., Inc. reported a gross profit of 13.34B and revenue of 16.29B. Therefore, the gross margin over that period was 81.9%.

BIIB - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Biogen Inc. reported an operating income of 0.00 and revenue of 2.48B, resulting in an operating margin of 0.0%.

MRK - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Merck & Co., Inc. reported an operating income of -1.88B and revenue of 16.29B, resulting in an operating margin of -11.6%.

BIIB - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Biogen Inc. reported a net income of 319.50M and revenue of 2.48B, resulting in a net margin of 12.9%.

MRK - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Merck & Co., Inc. reported a net income of -4.24B and revenue of 16.29B, resulting in a net margin of -26.0%.


Frequently Asked Questions


BIIB and MRK have a correlation of 0.46, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

BIIB has higher volatility (9.17%) compared to MRK (8.19%). In terms of maximum drawdown, BIIB dropped -89.98% vs MRK's -68.61%.

MRK currently has the higher Sharpe Ratio (2.14 vs 1.34), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for BIIB and MRK

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

Open Portfolio Optimizer