NAGE vs. VSGX

Last updated Jun 4, 2026

NAGE (Niagen Bioscience, Inc) is a stock, while VSGX (Vanguard ESG International Stock ETF) is Foreign Large Cap Equities fund tracking the FTSE Global All Cap ex US Choice Index.. Over the past 5 years, NAGE returned -17.39%/yr vs 7.81%/yr for VSGX. At a 0.32 correlation, their price movements are largely independent.

Performance

NAGE vs. VSGX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Niagen Bioscience, Inc (NAGE) and Vanguard ESG International Stock ETF (VSGX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, NAGE achieves a -45.91% return, which is significantly lower than VSGX's 15.83% return.

NAGE

• 1D: -2.82%
• 1M: -30.22%
• YTD: -45.91%
• 6M: -47.32%
• 1Y: -70.80%
• 3Y*: 31.29%
• 5Y*: -17.39%
• 10Y*: -5.02%

VSGX

• 1D: -0.94%
• 1M: 6.54%
• YTD: 15.83%
• 6M: 18.55%
• 1Y: 33.27%
• 3Y*: 19.56%
• 5Y*: 7.81%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

NAGE vs. VSGX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
NAGE Niagen Bioscience, Inc	-45.91%	19.89%	270.98%	-14.88%	-55.08%	-22.08%	11.37%	25.66%	-12.72%
VSGX Vanguard ESG International Stock ETF	15.83%	30.77%	5.72%	15.62%	-18.61%	7.24%	13.01%	23.04%	-12.87%

Correlation

The correlation between NAGE and VSGX is 0.38, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.38
Correlation (3Y) Calculated over the trailing 3-year period	0.24
Correlation (5Y) Calculated over the trailing 5-year period	0.34
Correlation (All Time) Calculated using the full available price history since Sep 21, 2018	0.32

The correlation between NAGE and VSGX shifts across timeframes, from 0.24 (3 years) to 0.38 (1 year), reflecting how their relationship changes across market environments.

Return for Risk

NAGE vs. VSGX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NAGE

NAGE Risk / Return Rank: 3
NAGE Sharpe Ratio Rank: 1
NAGE Sortino Ratio Rank: 1
NAGE Omega Ratio Rank: 2
NAGE Calmar Ratio Rank: 5
NAGE Martin Ratio Rank: 9

VSGX

VSGX Risk / Return Rank: 57
VSGX Sharpe Ratio Rank: 59
VSGX Sortino Ratio Rank: 58
VSGX Omega Ratio Rank: 60
VSGX Calmar Ratio Rank: 52
VSGX Martin Ratio Rank: 57

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NAGE vs. VSGX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Niagen Bioscience, Inc (NAGE) and Vanguard ESG International Stock ETF (VSGX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	NAGE	VSGX	Difference
Sharpe ratio: Return per unit of total volatility	-1.36	2.04	-3.40
Sortino ratio: Return per unit of downside risk	-2.54	2.82	-5.36
Omega ratio: Gain probability vs. loss probability	0.70	1.37	-0.67
Calmar ratio: Return relative to maximum drawdown	-0.93	2.60	-3.53
Martin ratio: Return relative to average drawdown	-1.36	10.13	-11.48
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

NAGE vs. VSGX - Sharpe Ratio Comparison

The current NAGE Sharpe Ratio is -1.36, which is lower than the VSGX Sharpe Ratio of 2.04. The chart below compares the historical Sharpe Ratios of NAGE and VSGX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	NAGE	VSGX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-1.36	2.04	-3.40
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.23	0.48	-0.71
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.06	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.03	0.51	-0.54

Drawdowns

NAGE vs. VSGX - Drawdown Comparison

The maximum NAGE drawdown since its inception was -97.00%, which is greater than VSGX's maximum drawdown of -33.09%. Use the drawdown chart below to compare losses from any high point for NAGE and VSGX.

Drawdown Indicators

	NAGE	VSGX	Difference
Max Drawdown Largest peak-to-trough decline	-97.00%	-33.09%	-63.91%
Max Drawdown (1Y) Largest decline over 1 year	-76.13%	-12.84%	-63.29%
Max Drawdown (3Y) Largest decline over 3 years	-76.13%	-13.83%	-62.30%
Max Drawdown (5Y) Largest decline over 5 years	-88.71%	-32.14%	-56.57%
Max Drawdown (10Y) Largest decline over 10 years	-93.65%	—	—
Current Drawdown Current decline from peak	-81.64%	-0.94%	-80.70%
Average Drawdown Average peak-to-trough decline	-75.72%	-7.78%	-67.94%
Ulcer Index Depth and duration of drawdowns from previous peaks	52.25%	3.29%	+48.96%

Volatility

NAGE vs. VSGX - Volatility Comparison

Niagen Bioscience, Inc (NAGE) has a higher volatility of 20.67% compared to Vanguard ESG International Stock ETF (VSGX) at 6.06%. This indicates that NAGE's price experiences larger fluctuations and is considered to be riskier than VSGX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	NAGE	VSGX	Difference
Volatility (1M) Calculated over the trailing 1-month period	20.67%	6.06%	+14.61%
Volatility (6M) Calculated over the trailing 6-month period	34.51%	14.12%	+20.39%
Volatility (1Y) Calculated over the trailing 1-year period	52.25%	16.38%	+35.87%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	77.24%	16.31%	+60.93%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	80.01%	18.05%	+61.96%

Dividends

NAGE vs. VSGX - Dividend Comparison

NAGE has not paid dividends to shareholders, while VSGX's dividend yield for the trailing twelve months is around 2.85%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018
NAGE Niagen Bioscience, Inc	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
VSGX Vanguard ESG International Stock ETF	2.85%	3.23%	3.10%	2.77%	2.61%	2.49%	1.67%	2.28%	0.38%

Frequently Asked Questions

Can I hold both NAGE and VSGX in my portfolio?

NAGE and VSGX have a correlation of 0.38, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, NAGE or VSGX?

NAGE has higher volatility (20.67%) compared to VSGX (6.06%). In terms of maximum drawdown, NAGE dropped -97.00% vs VSGX's -33.09%.

Which has better risk-adjusted returns?

VSGX currently has the higher Sharpe Ratio (2.04 vs -1.36), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.