MLTX vs. SRRK

Last updated Aug 1, 2026

MLTX (MoonLake Immunotherapeutics) and SRRK (Scholar Rock Holding Corporation) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, MLTX returned 13.20%/yr vs 8.64%/yr for SRRK. Their 0.20 correlation means their historical movements had little consistent relationship.

Performance

MLTX vs. SRRK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in MoonLake Immunotherapeutics (MLTX) and Scholar Rock Holding Corporation (SRRK). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, MLTX achieves a 39.91% return, which is significantly higher than SRRK's 7.37% return.

MLTX

• 1D: -2.90%
• 1M: -2.69%
• 6M: 17.68%
• YTD: 39.91%
• 1Y: -65.15%
• 3Y*: -31.69%
• 5Y*: 13.20%
• 10Y*: —
• ALL TIME*: 10.87%

SRRK

• 1D: -3.46%
• 1M: -13.82%
• 6M: 6.66%
• YTD: 7.37%
• 1Y: 30.07%
• 3Y*: 90.42%
• 5Y*: 8.64%
• 10Y*: —
• ALL TIME*: 15.78%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
MLTX MoonLake Immunotherapeutics	$16.11M	$20.69M	$21.49M
SRRK Scholar Rock Holding Corporation	$55.73M	$56.96M	$69.55M

MLTX vs. SRRK - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
MLTX MoonLake Immunotherapeutics	39.91%	-75.66%	-10.33%	475.14%	6.17%	-13.02%	11.91%
SRRK Scholar Rock Holding Corporation	7.37%	1.92%	129.89%	107.73%	-63.57%	-48.82%	233.77%

Correlation

The correlation between MLTX and SRRK is 0.35, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.35
Correlation (3Y) Balances recent behavior with more history.	0.34
Correlation (5Y) Shows whether the relationship held over a longer period.	0.24
Correlation (All Time) Calculated using the full available price history since Oct 20, 2020	0.20

The correlation between MLTX and SRRK shifts across timeframes, from 0.20 (all time) to 0.35 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap MLTX : $1.55B SRRK : $5.67B
EPS MLTX : -$3.85 SRRK : -$3.45
PB Ratio MLTX : 5.17 SRRK : 21.81
Total Revenue (TTM) MLTX : $0.00 SRRK : $0.00
Gross Profit (TTM) MLTX : -$1.49M SRRK : -$1.27M
EBITDA (TTM) MLTX : -$179.84M SRRK : -$394.71M

Return for Risk

MLTX vs. SRRK — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

MLTX

MLTX Risk / Return Rank: 35
MLTX Sharpe Ratio Rank: 20
MLTX Sortino Ratio Rank: 50
MLTX Omega Ratio Rank: 64
MLTX Calmar Ratio Rank: 17
MLTX Martin Ratio Rank: 24

SRRK

SRRK Risk / Return Rank: 63
SRRK Sharpe Ratio Rank: 60
SRRK Sortino Ratio Rank: 63
SRRK Omega Ratio Rank: 60
SRRK Calmar Ratio Rank: 64
SRRK Martin Ratio Rank: 67

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

MLTX vs. SRRK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for MoonLake Immunotherapeutics (MLTX) and Scholar Rock Holding Corporation (SRRK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	MLTX	SRRK	Difference
Sharpe ratio: Return per unit of total volatility	-0.54	0.45	-0.99
Sortino ratio: Return per unit of downside risk	0.67	1.16	-0.49
Omega ratio: Gain probability vs. loss probability	1.16	1.14	+0.02
Calmar ratio: Return relative to maximum drawdown	-0.71	0.87	-1.58
Martin ratio: Return relative to average drawdown	-0.93	2.38	-3.31

MLTX vs. SRRK - Sharpe Ratio Comparison

The current MLTX Sharpe Ratio is -0.54, which is lower than the SRRK Sharpe Ratio of 0.45. The chart below compares the historical Sharpe Ratios of MLTX and SRRK, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

MLTX vs. SRRK - Drawdown Comparison

The maximum MLTX drawdown since its inception was -90.22%, roughly equal to the maximum SRRK drawdown of -93.15%. Use the drawdown chart below to compare losses from any high point for MLTX and SRRK.

Drawdown Indicators

	MLTX	SRRK	Difference
Max Drawdown Largest peak-to-trough decline	-90.22%	-93.15%	+2.93%
Max Drawdown (1Y) Largest decline over 1 year	-89.93%	-31.89%	-58.04%
Max Drawdown (3Y) Largest decline over 3 years	-90.22%	-65.21%	-25.01%
Max Drawdown (5Y) Largest decline over 5 years	-90.22%	-88.96%	-1.26%
Current Drawdown Current decline from peak	-71.12%	-30.47%	-40.65%
Average Drawdown Average peak-to-trough decline	-30.25%	-55.85%	+25.60%
Ulcer Index Depth and duration of drawdowns from previous peaks	68.46%	11.67%	+56.79%

Volatility

MLTX vs. SRRK - Volatility Comparison

MoonLake Immunotherapeutics (MLTX) has a higher volatility of 16.02% compared to Scholar Rock Holding Corporation (SRRK) at 12.80%. This indicates that MLTX's price experiences larger fluctuations and is considered to be riskier than SRRK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MLTX	SRRK	Difference
Volatility (1M) Calculated over the trailing 1-month period	16.02%	12.80%	+3.22%
Volatility (6M) Calculated over the trailing 6-month period	42.92%	35.23%	+7.69%
Volatility (1Y) Calculated over the trailing 1-year period	117.23%	62.28%	+54.95%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	91.77%	180.10%	-88.33%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	85.91%	156.39%	-70.48%

Dividends

MLTX vs. SRRK - Dividend Comparison

Neither MLTX nor SRRK has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both MLTX and SRRK in my portfolio?

MLTX and SRRK have a correlation of 0.35, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, MLTX or SRRK?

MLTX has higher volatility (16.02%) compared to SRRK (12.80%). In terms of maximum drawdown, MLTX dropped -90.22% vs SRRK's -93.15%.

Which has better risk-adjusted returns?

SRRK currently has the higher Sharpe Ratio (0.45 vs -0.54), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.