MIST vs. VPU
MIST (Milestone Pharmaceuticals Inc.) is a stock, while VPU (Vanguard Utilities ETF) is Utilities Equities fund tracking the MSCI US Investable Market Utilities 25/50 Index. Over the past 5 years, MIST returned -27.37%/yr vs 8.88%/yr for VPU. Their 0.10 correlation means their historical movements had little consistent relationship.
Performance
MIST vs. VPU - Performance Comparison
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Returns By Period
In the year-to-date period, MIST achieves a -44.55% return, which is significantly lower than VPU's 4.90% return.
MIST
- 1D
- 0.90%
- 1M
- -15.15%
- 6M
- -42.86%
- YTD
- -44.55%
- 1Y
- -21.68%
- 3Y*
- -28.23%
- 5Y*
- -27.37%
- 10Y*
- —
- ALL TIME*
- -30.52%
VPU
- 1D
- 0.17%
- 1M
- -3.03%
- 6M
- 4.79%
- YTD
- 4.90%
- 1Y
- 6.21%
- 3Y*
- 14.72%
- 5Y*
- 8.88%
- 10Y*
- 8.98%
- ALL TIME*
- 9.72%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $1.43M | $1.38M | $1.89M | |
| $43.88M | $41.86M | $43.70M |
MIST vs. VPU - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
MIST Milestone Pharmaceuticals Inc. | -44.55% | -14.41% | 41.32% | -57.83% | -39.54% | -2.24% | -58.15% | 2.56% |
VPU Vanguard Utilities ETF | 4.90% | 16.46% | 23.04% | -7.45% | 1.06% | 17.40% | -0.74% | 14.91% |
Correlation
The correlation between MIST and VPU is 0.05, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.05 |
Correlation (3Y) Balances recent behavior with more history. | 0.08 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.10 |
Correlation (All Time) Calculated using the full available price history since May 9, 2019 | 0.10 |
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Return for Risk
MIST vs. VPU — Risk / Return Rank
MIST
VPU
MIST vs. VPU - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Milestone Pharmaceuticals Inc. (MIST) and Vanguard Utilities ETF (VPU). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| MIST | VPU | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.73 | ||
| Sortino ratioReturn per unit of downside risk | -0.67 | ||
| Omega ratioGain probability vs. loss probability | 1.00 | 1.08 | -0.08 |
| Calmar ratioReturn relative to maximum drawdown | -0.33 | 0.70 | -1.03 |
| Martin ratioReturn relative to average drawdown | -0.59 | 1.43 | -2.03 |
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Drawdowns
MIST vs. VPU - Drawdown Comparison
The maximum MIST drawdown since its inception was -97.60%, which is greater than VPU's maximum drawdown of -46.31%. Use the drawdown chart below to compare losses from any high point for MIST and VPU.
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Drawdown Indicators
| MIST | VPU | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.60% | -46.31% | -51.29% |
Max Drawdown (1Y)Largest decline over 1 year | -65.76% | -8.90% | -56.86% |
Max Drawdown (3Y)Largest decline over 3 years | -81.18% | -12.95% | -68.23% |
Max Drawdown (5Y)Largest decline over 5 years | -93.13% | -25.15% | -67.98% |
Max Drawdown (10Y)Largest decline over 10 years | — | -36.42% | — |
Current DrawdownCurrent decline from peak | -95.87% | -5.72% | -90.15% |
Average DrawdownAverage peak-to-trough decline | -78.61% | -7.76% | -70.85% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 36.62% | 4.34% | +32.28% |
Volatility
MIST vs. VPU - Volatility Comparison
Milestone Pharmaceuticals Inc. (MIST) has a higher volatility of 18.14% compared to Vanguard Utilities ETF (VPU) at 3.79%. This indicates that MIST's price experiences larger fluctuations and is considered to be riskier than VPU based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| MIST | VPU | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 18.14% | 3.79% | +14.35% |
Volatility (6M)Calculated over the trailing 6-month period | 55.16% | 11.79% | +43.37% |
Volatility (1Y)Calculated over the trailing 1-year period | 70.65% | 14.73% | +55.92% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 78.01% | 17.05% | +60.96% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 104.44% | 19.17% | +85.27% |
Dividends
MIST vs. VPU - Dividend Comparison
MIST has not paid dividends to shareholders, while VPU's dividend yield for the trailing twelve months is around 2.70%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
MIST Milestone Pharmaceuticals Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
VPU Vanguard Utilities ETF | 2.70% | 2.73% | 3.02% | 3.49% | 2.98% | 2.70% | 3.17% | 2.83% | 3.23% | 3.18% | 3.19% | 3.63% |
Frequently Asked Questions
MIST and VPU have a correlation of 0.05, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
MIST has higher volatility (18.14%) compared to VPU (3.79%). In terms of maximum drawdown, MIST dropped -97.60% vs VPU's -46.31%.
VPU currently has the higher Sharpe Ratio (0.42 vs -0.31), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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