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Milestone Pharmaceuticals Inc. (MIST)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
CA59935V1076
CUSIP
59935V107
IPO Date
May 9, 2019

Highlights

Market Cap
$99.82M
Enterprise Value
$85.80M
EPS (TTM)
-$1.10
Total Revenue (TTM)
$1.44M
Gross Profit (TTM)
-$80.00K
EBITDA (TTM)
-$62.14M
Year Range
$0.63 - $3.06
Target Price
$8.00
ROA (TTM)
-69.90%
ROE (TTM)
-190.04%

Share Price Chart


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Milestone Pharmaceuticals Inc.

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Milestone Pharmaceuticals Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

Milestone Pharmaceuticals Inc. (MIST) has returned -41.09% so far this year and 48.73% over the past 12 months.


Milestone Pharmaceuticals Inc.

1D
17.82%
1M
-30.41%
YTD
-41.09%
6M
-40.50%
1Y
48.73%
3Y*
-32.91%
5Y*
-27.76%
10Y*

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since May 9, 2019, MIST's average daily return is +0.09%, while the average monthly return is +1.71%. At this rate, your investment would double in approximately 3.4 years.

Historically, 48% of months were positive and 52% were negative. The best month was Jul 2020 with a return of +130.2%, while the worst month was Mar 2020 at -90.3%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 5 months.

On a daily basis, MIST closed higher 46% of trading days. The best single day was Jul 23, 2020 with a return of +166.8%, while the worst single day was Mar 24, 2020 at -87.9%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-5.45%-10.47%-30.41%-41.09%
2025-16.53%-17.26%-50.91%64.98%22.73%19.75%-25.26%26.90%8.70%-4.00%40.10%-24.91%-14.41%
2024-4.19%5.00%6.55%-7.82%-9.09%-12.00%9.09%-1.39%7.04%-4.61%37.24%18.59%41.32%
2023-7.58%-13.66%24.68%-7.87%8.54%-27.66%13.33%-17.03%15.67%-17.42%30.47%-50.00%-57.83%
20225.95%-28.67%29.70%3.58%-15.64%9.63%21.14%16.24%6.12%-45.38%-2.19%-19.35%-39.54%
202110.15%-2.57%-19.47%1.21%3.24%-9.09%3.64%6.49%-5.93%-1.40%-2.84%19.74%-2.24%

Benchmark Metrics

Milestone Pharmaceuticals Inc. has an annualized alpha of 18.60%, beta of 0.45, and R² of 0.01 versus S&P 500 Index. Calculated based on daily prices since May 10, 2019.

  • This stock participated in 193.92% of S&P 500 Index downside but only 39.23% of its upside — more exposed to losses than it benefited from rallies.
  • Beta of 0.45 may look defensive, but with R² of 0.01 this stock is largely uncorrelated with S&P 500 Index — low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
  • R² of 0.01 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
18.60%
Beta
0.45
0.01
Upside Capture
39.23%
Downside Capture
193.92%

Return for Risk

Risk / Return Rank

MIST ranks 59 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


MIST Risk / Return Rank: 5959
Overall Rank
MIST Sharpe Ratio Rank: 6161
Sharpe Ratio Rank
MIST Sortino Ratio Rank: 6161
Sortino Ratio Rank
MIST Omega Ratio Rank: 6565
Omega Ratio Rank
MIST Calmar Ratio Rank: 5454
Calmar Ratio Rank
MIST Martin Ratio Rank: 5454
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Milestone Pharmaceuticals Inc. (MIST) and compare them to a chosen benchmark (S&P 500 Index).


MISTBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.57

0.90

-0.33

Sortino ratio

Return per unit of downside risk

1.27

1.39

-0.11

Omega ratio

Gain probability vs. loss probability

1.19

1.21

-0.02

Calmar ratio

Return relative to maximum drawdown

0.54

1.40

-0.86

Martin ratio

Return relative to average drawdown

1.24

6.61

-5.37

Explore MIST risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Milestone Pharmaceuticals Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Milestone Pharmaceuticals Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Milestone Pharmaceuticals Inc. was 97.60%, occurring on Apr 8, 2025. The portfolio has not yet recovered.

The current Milestone Pharmaceuticals Inc. drawdown is 95.62%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-97.6%Jul 1, 20191452Apr 8, 2025
-12.42%May 29, 201910Jun 11, 20194Jun 17, 201914
-8.54%Jun 20, 20193Jun 24, 20194Jun 28, 20197
-4.2%May 23, 20191May 23, 20192May 28, 20193
-1.58%May 17, 20191May 17, 20191May 20, 20192

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Milestone Pharmaceuticals Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Milestone Pharmaceuticals Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for MIST relative to other companies in the Biotechnology industry. Currently, MIST has a P/S ratio of 59.8. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for MIST in comparison with other companies in the Biotechnology industry. Currently, MIST has a P/B value of 2.4. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items