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MEDP vs. CPRX
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

MEDP vs. CPRX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Medpace Holdings, Inc. (MEDP) and Catalyst Pharmaceuticals, Inc. (CPRX). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, MEDP achieves a 2.75% return, which is significantly lower than CPRX's 34.92% return.


MEDP

1D
-0.21%
1M
3.50%
6M
-0.92%
YTD
2.75%
1Y
36.40%
3Y*
31.18%
5Y*
26.82%
10Y*
ALL TIME*
35.39%

CPRX

1D
0.00%
1M
0.13%
6M
29.59%
YTD
34.92%
1Y
49.10%
3Y*
32.72%
5Y*
41.46%
10Y*
44.91%
ALL TIME*
8.79%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$292.94M$222.04M$171.72M

MEDP vs. CPRX - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
MEDP
Medpace Holdings, Inc.
2.75%69.05%8.38%44.31%-2.40%56.35%65.60%58.81%45.97%0.53%
CPRX
Catalyst Pharmaceuticals, Inc.
34.92%11.84%24.15%-9.62%174.74%102.69%-10.93%95.31%-50.90%272.38%

Correlation

The correlation between MEDP and CPRX is 0.23, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.23

Correlation (3Y)
Balances recent behavior with more history.

0.28

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.34

Correlation (All Time)
Calculated using the full available price history since Aug 11, 2016

0.28

The correlation between MEDP and CPRX shifts across timeframes, from 0.23 (1 year) to 0.34 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap

MEDP:

$16.11B

CPRX:

$3.85B

EPS

MEDP:

$16.89

CPRX:

$1.74

PE Ratio

MEDP:

34.17

CPRX:

18.08

PEG Ratio

MEDP:

1.03

CPRX:

0.32

PS Ratio

MEDP:

6.04

CPRX:

6.70

PB Ratio

MEDP:

38.26

CPRX:

3.95

Total Revenue (TTM)

MEDP:

$2.78B

CPRX:

$596.96M

Gross Profit (TTM)

MEDP:

$800.22M

CPRX:

$378.23M

EBITDA (TTM)

MEDP:

$613.10M

CPRX:

$313.50M

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Return for Risk

MEDP vs. CPRX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

MEDP
MEDP Risk / Return Rank: 6868
Overall Rank
MEDP Sharpe Ratio Rank: 7171
Sharpe Ratio Rank
MEDP Sortino Ratio Rank: 6464
Sortino Ratio Rank
MEDP Omega Ratio Rank: 7373
Omega Ratio Rank
MEDP Calmar Ratio Rank: 6666
Calmar Ratio Rank
MEDP Martin Ratio Rank: 6565
Martin Ratio Rank

CPRX

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

MEDP vs. CPRX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Medpace Holdings, Inc. (MEDP) and Catalyst Pharmaceuticals, Inc. (CPRX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


MEDPCPRXDifference
Sharpe ratioReturn per unit of total volatility

-0.75

Sortino ratioReturn per unit of downside risk

-0.93

Omega ratioGain probability vs. loss probability

1.21

1.31

-0.10

Calmar ratioReturn relative to maximum drawdown

0.96

3.52

-2.55

Martin ratioReturn relative to average drawdown

2.04

9.42

-7.38

MEDP vs. CPRX - Sharpe Ratio Comparison

The current MEDP Sharpe Ratio is 0.79, which is lower than the CPRX Sharpe Ratio of 1.54. The chart below compares the historical Sharpe Ratios of MEDP and CPRX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

MEDP vs. CPRX - Drawdown Comparison

The maximum MEDP drawdown since its inception was -42.87%, smaller than the maximum CPRX drawdown of -94.25%. Use the drawdown chart below to compare losses from any high point for MEDP and CPRX.


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Drawdown Indicators


MEDPCPRXDifference

Max Drawdown

Largest peak-to-trough decline

-42.87%

-94.25%

+51.38%

Max Drawdown (1Y)

Largest decline over 1 year

-36.61%

-13.91%

-22.70%

Max Drawdown (3Y)

Largest decline over 3 years

-39.38%

-27.29%

-12.09%

Max Drawdown (5Y)

Largest decline over 5 years

-42.87%

-45.37%

+2.50%

Max Drawdown (10Y)

Largest decline over 10 years

-64.87%

Current Drawdown

Current decline from peak

-7.01%

-0.03%

-6.98%

Average Drawdown

Average peak-to-trough decline

-12.94%

-51.73%

+38.79%

Ulcer Index

Depth and duration of drawdowns from previous peaks

17.24%

5.18%

+12.06%

Volatility

MEDP vs. CPRX - Volatility Comparison

Medpace Holdings, Inc. (MEDP) has a higher volatility of 16.14% compared to Catalyst Pharmaceuticals, Inc. (CPRX) at 0.41%. This indicates that MEDP's price experiences larger fluctuations and is considered to be riskier than CPRX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


MEDPCPRXDifference

Volatility (1M)

Calculated over the trailing 1-month period

16.14%

0.41%

+15.73%

Volatility (6M)

Calculated over the trailing 6-month period

41.25%

21.80%

+19.45%

Volatility (1Y)

Calculated over the trailing 1-year period

44.64%

31.77%

+12.87%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

52.09%

47.65%

+4.44%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

49.81%

59.86%

-10.05%

Dividends

MEDP vs. CPRX - Dividend Comparison

Neither MEDP nor CPRX has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

MEDP vs. CPRX - Financials Comparison

This section allows you to compare key financial metrics between Medpace Holdings, Inc. and Catalyst Pharmaceuticals, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

MEDP vs. CPRX - Profitability Comparison

The chart below illustrates the profitability comparison between Medpace Holdings, Inc. and Catalyst Pharmaceuticals, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

MEDP - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Medpace Holdings, Inc. reported a gross profit of 201.64M and revenue of 707.33M. Therefore, the gross margin over that period was 28.5%.

CPRX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Catalyst Pharmaceuticals, Inc. reported a gross profit of 0.00 and revenue of 149.39M. Therefore, the gross margin over that period was 0.0%.

MEDP - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Medpace Holdings, Inc. reported an operating income of 146.82M and revenue of 707.33M, resulting in an operating margin of 20.8%.

CPRX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Catalyst Pharmaceuticals, Inc. reported an operating income of 73.23M and revenue of 149.39M, resulting in an operating margin of 49.0%.

MEDP - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Medpace Holdings, Inc. reported a net income of 121.36M and revenue of 707.33M, resulting in a net margin of 17.2%.

CPRX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Catalyst Pharmaceuticals, Inc. reported a net income of 63.73M and revenue of 149.39M, resulting in a net margin of 42.7%.


Frequently Asked Questions


MEDP and CPRX have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

MEDP has higher volatility (16.14%) compared to CPRX (0.41%). In terms of maximum drawdown, MEDP dropped -42.87% vs CPRX's -94.25%.

CPRX currently has the higher Sharpe Ratio (1.54 vs 0.79), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for MEDP and CPRX

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