MDXG vs. TNGX

Last updated Jun 3, 2026

MDXG (MiMedx Group, Inc.) and TNGX (Tango Therapeutics, Inc.) are both stocks. Both are in the Healthcare sector — MDXG in Medical Devices, TNGX in Biotechnology. Over the past 5 years, MDXG returned -19.16%/yr vs 14.39%/yr for TNGX. At a 0.23 correlation, their price movements are largely independent.

Performance

MDXG vs. TNGX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in MiMedx Group, Inc. (MDXG) and Tango Therapeutics, Inc. (TNGX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, MDXG achieves a -47.27% return, which is significantly lower than TNGX's 142.66% return.

MDXG

• 1D: -0.28%
• 1M: -2.99%
• YTD: -47.27%
• 6M: -46.88%
• 1Y: -44.13%
• 3Y*: -14.84%
• 5Y*: -19.16%
• 10Y*: -7.99%

TNGX

• 1D: -6.93%
• 1M: 2.48%
• YTD: 142.66%
• 6M: 113.29%
• 1Y: 746.46%
• 3Y*: 88.89%
• 5Y*: 14.39%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

MDXG vs. TNGX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
MDXG MiMedx Group, Inc.	-47.27%	-29.63%	9.69%	215.47%	-53.97%	-33.48%	37.58%
TNGX Tango Therapeutics, Inc.	142.66%	186.73%	-68.79%	36.55%	-33.73%	-4.37%	11.83%

Correlation

The correlation between MDXG and TNGX is 0.10, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.10
Correlation (3Y) Calculated over the trailing 3-year period	0.21
Correlation (5Y) Calculated over the trailing 5-year period	0.24
Correlation (All Time) Calculated using the full available price history since Sep 4, 2020	0.23

The correlation between MDXG and TNGX shifts across timeframes, from 0.10 (1 year) to 0.24 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap MDXG : $529.95M TNGX : $3.09B
EPS MDXG : $0.21 TNGX : -$0.89
PS Ratio MDXG : 1.37 TNGX : 45.39
PB Ratio MDXG : 2.18 TNGX : 7.88
Total Revenue (TTM) MDXG : $389.42M TNGX : $56.99M
Gross Profit (TTM) MDXG : $315.59M TNGX : $55.33M
EBITDA (TTM) MDXG : $53.81M TNGX : -$111.92M

Return for Risk

MDXG vs. TNGX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MDXG

MDXG Risk / Return Rank: 7
MDXG Sharpe Ratio Rank: 4
MDXG Sortino Ratio Rank: 5
MDXG Omega Ratio Rank: 6
MDXG Calmar Ratio Rank: 13
MDXG Martin Ratio Rank: 5

TNGX

TNGX Risk / Return Rank: 99
TNGX Sharpe Ratio Rank: 100
TNGX Sortino Ratio Rank: 98
TNGX Omega Ratio Rank: 97
TNGX Calmar Ratio Rank: 100
TNGX Martin Ratio Rank: 100

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MDXG vs. TNGX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for MiMedx Group, Inc. (MDXG) and Tango Therapeutics, Inc. (TNGX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	MDXG	TNGX	Difference
Sharpe ratio Return per unit of total volatility	-1.04	8.28	-9.31
Sortino ratio Return per unit of downside risk	-1.56	5.67	-7.23
Omega ratio Gain probability vs. loss probability	0.82	1.70	-0.89
Calmar ratio Return relative to maximum drawdown	-0.73	29.70	-30.43
Martin ratio Return relative to average drawdown	-1.49	79.51	-81.01
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

MDXG vs. TNGX - Sharpe Ratio Comparison

The current MDXG Sharpe Ratio is -1.04, which is lower than the TNGX Sharpe Ratio of 8.28. The chart below compares the historical Sharpe Ratios of MDXG and TNGX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	MDXG	TNGX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-1.04	8.28	-9.31
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.31	0.15	-0.46
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.11	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.06	0.15	-0.09

Drawdowns

MDXG vs. TNGX - Drawdown Comparison

The maximum MDXG drawdown since its inception was -93.83%, roughly equal to the maximum TNGX drawdown of -93.64%. Use the drawdown chart below to compare losses from any high point for MDXG and TNGX.

Drawdown Indicators

	MDXG	TNGX	Difference
Max Drawdown Largest peak-to-trough decline	-93.83%	-93.64%	-0.19%
Max Drawdown (1Y) Largest decline over 1 year	-61.24%	-29.24%	-32.00%
Max Drawdown (3Y) Largest decline over 3 years	-68.36%	-91.46%	+23.10%
Max Drawdown (5Y) Largest decline over 5 years	-83.39%	-93.64%	+10.25%
Max Drawdown (10Y) Largest decline over 10 years	-93.60%	—	—
Current Drawdown Current decline from peak	-80.12%	-22.58%	-57.54%
Average Drawdown Average peak-to-trough decline	-53.50%	-48.22%	-5.28%
Ulcer Index Depth and duration of drawdowns from previous peaks	29.79%	10.92%	+18.87%

Volatility

MDXG vs. TNGX - Volatility Comparison

The current volatility for MiMedx Group, Inc. (MDXG) is 8.66%, while Tango Therapeutics, Inc. (TNGX) has a volatility of 28.86%. This indicates that MDXG experiences smaller price fluctuations and is considered to be less risky than TNGX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MDXG	TNGX	Difference
Volatility (1M) Calculated over the trailing 1-month period	8.66%	28.86%	-20.20%
Volatility (6M) Calculated over the trailing 6-month period	30.99%	64.74%	-33.75%
Volatility (1Y) Calculated over the trailing 1-year period	42.76%	92.04%	-49.28%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	62.11%	99.00%	-36.89%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	73.92%	93.56%	-19.64%

Dividends

MDXG vs. TNGX - Dividend Comparison

Neither MDXG nor TNGX has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both MDXG and TNGX in my portfolio?

MDXG and TNGX have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, MDXG or TNGX?

TNGX has higher volatility (28.86%) compared to MDXG (8.66%). In terms of maximum drawdown, MDXG dropped -93.83% vs TNGX's -93.64%.

Which has better risk-adjusted returns?

TNGX currently has the higher Sharpe Ratio (8.28 vs -1.04), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.