LSEQ vs. MEDI

Last updated Jun 4, 2026

LSEQ (Harbor Long-Short Equity ETF) and MEDI (Harbor Health Care ETF) are both exchange-traded funds - LSEQ is a Long-Short fund actively managed by Harbor, while MEDI is a Health & Biotech Equities fund actively managed by Harbor. Both are actively managed. Over the past year, LSEQ returned 25.44% vs 18.27% for MEDI. At a 0.14 correlation, their price movements are largely independent. LSEQ charges 1.70%/yr vs 0.80%/yr for MEDI.

Performance

LSEQ vs. MEDI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Harbor Long-Short Equity ETF (LSEQ) and Harbor Health Care ETF (MEDI). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, LSEQ achieves a 27.40% return, which is significantly higher than MEDI's -4.02% return.

LSEQ

• 1D: 1.12%
• 1M: 4.34%
• YTD: 27.40%
• 6M: 26.84%
• 1Y: 25.44%
• 3Y*: —
• 5Y*: —
• 10Y*: —

MEDI

• 1D: 1.06%
• 1M: -0.93%
• YTD: -4.02%
• 6M: -4.83%
• 1Y: 18.27%
• 3Y*: 12.46%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

LSEQ vs. MEDI - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023
LSEQ Harbor Long-Short Equity ETF	27.40%	4.13%	12.80%	-1.20%
MEDI Harbor Health Care ETF	-4.02%	27.11%	0.58%	7.06%

Correlation

The correlation between LSEQ and MEDI is 0.18, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.18
Correlation (All Time) Calculated using the full available price history since Dec 5, 2023	0.14

LSEQ vs. MEDI - Sectors Allocation Comparison

Sectors	LSEQ	MEDI
Basic Materials	27.3%	-
Consumer Cyclical	17.3%	-
Energy	15.0%	-
Healthcare	14.7%	100.0%
Communication Services	7.0%	-
Industrials	6.5%	-
Consumer Defensive	5.2%	-
Utilities	3.1%	-
Financial Services	1.2%	-
Real Estate	-	-
Technology	-10.9%	-

Return for Risk

LSEQ vs. MEDI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

LSEQ

LSEQ Risk / Return Rank: 54
LSEQ Sharpe Ratio Rank: 49
LSEQ Sortino Ratio Rank: 48
LSEQ Omega Ratio Rank: 49
LSEQ Calmar Ratio Rank: 69
LSEQ Martin Ratio Rank: 55

MEDI

MEDI Risk / Return Rank: 26
MEDI Sharpe Ratio Rank: 26
MEDI Sortino Ratio Rank: 27
MEDI Omega Ratio Rank: 24
MEDI Calmar Ratio Rank: 25
MEDI Martin Ratio Rank: 26

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

LSEQ vs. MEDI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Harbor Long-Short Equity ETF (LSEQ) and Harbor Health Care ETF (MEDI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	LSEQ	MEDI	Difference
Sharpe ratio: Return per unit of total volatility	1.70	0.93	+0.77
Sortino ratio: Return per unit of downside risk	2.38	1.46	+0.92
Omega ratio: Gain probability vs. loss probability	1.31	1.17	+0.14
Calmar ratio: Return relative to maximum drawdown	3.45	1.20	+2.26
Martin ratio: Return relative to average drawdown	9.40	3.59	+5.81
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

LSEQ vs. MEDI - Sharpe Ratio Comparison

The current LSEQ Sharpe Ratio is 1.70, which is higher than the MEDI Sharpe Ratio of 0.93. The chart below compares the historical Sharpe Ratios of LSEQ and MEDI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	LSEQ	MEDI	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.70	0.93	+0.77
Sharpe Ratio (All Time) Calculated using the full available price history	1.19	0.74	+0.46

Drawdowns

LSEQ vs. MEDI - Drawdown Comparison

The maximum LSEQ drawdown since its inception was -8.35%, smaller than the maximum MEDI drawdown of -19.24%. Use the drawdown chart below to compare losses from any high point for LSEQ and MEDI.

Drawdown Indicators

	LSEQ	MEDI	Difference
Max Drawdown Largest peak-to-trough decline	-8.35%	-19.24%	+10.89%
Max Drawdown (1Y) Largest decline over 1 year	-7.40%	-15.34%	+7.94%
Max Drawdown (3Y) Largest decline over 3 years	—	-19.24%	—
Current Drawdown Current decline from peak	-1.66%	-8.01%	+6.35%
Average Drawdown Average peak-to-trough decline	-3.23%	-4.28%	+1.05%
Ulcer Index Depth and duration of drawdowns from previous peaks	2.78%	5.10%	-2.32%

Volatility

LSEQ vs. MEDI - Volatility Comparison

The current volatility for Harbor Long-Short Equity ETF (LSEQ) is 5.48%, while Harbor Health Care ETF (MEDI) has a volatility of 6.02%. This indicates that LSEQ experiences smaller price fluctuations and is considered to be less risky than MEDI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	LSEQ	MEDI	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.48%	6.02%	-0.54%
Volatility (6M) Calculated over the trailing 6-month period	12.75%	15.42%	-2.67%
Volatility (1Y) Calculated over the trailing 1-year period	15.09%	19.82%	-4.73%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	14.32%	18.63%	-4.31%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	14.32%	18.63%	-4.31%

LSEQ vs. MEDI - Expense Ratio Comparison

LSEQ has a 1.70% expense ratio, which is higher than MEDI's 0.80% expense ratio.

Dividends

LSEQ vs. MEDI - Dividend Comparison

LSEQ's dividend yield for the trailing twelve months is around 1.73%, more than MEDI's 0.29% yield.

Position	TTM	2025	2024	2023
LSEQ Harbor Long-Short Equity ETF	1.73%	2.20%	0.00%	0.00%
MEDI Harbor Health Care ETF	0.29%	0.28%	0.54%	1.86%

Frequently Asked Questions

Can I hold both LSEQ and MEDI in my portfolio?

LSEQ and MEDI have a correlation of 0.18, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, LSEQ or MEDI?

MEDI has higher volatility (6.02%) compared to LSEQ (5.48%). In terms of maximum drawdown, LSEQ dropped -8.35% vs MEDI's -19.24%.

Which ETF is better, LSEQ or MEDI?

On 1-year performance, LSEQ leads with 25.44% vs 18.27% for MEDI. On fees, MEDI is cheaper at 0.80% per year. On volatility, LSEQ has been the lower-risk option at 5.48%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, LSEQ or MEDI?

Over the 1-year period, LSEQ has performed better with a 25.44% return vs 18.27%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, LSEQ or MEDI?

MEDI is cheaper with a 0.80% expense ratio, compared with 1.70% for LSEQ.

Which ETF pays a higher dividend yield, LSEQ or MEDI?

LSEQ has the higher dividend yield at 1.73%, compared with 0.29% for MEDI.

What is the main difference between LSEQ and MEDI?

LSEQ is categorized as Long-Short, while MEDI is Health & Biotech Equities. Their fees differ too: 1.70% for LSEQ and 0.80% for MEDI.

Which has better risk-adjusted returns?

LSEQ currently has the higher Sharpe Ratio (1.70 vs 0.93), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.