KURE vs. PILL

Last updated Jun 3, 2026

KURE (KraneShares MSCI All China Health Care Index ETF) and PILL (Direxion Daily Pharmaceutical & Medical Bull 3X Shares) are both exchange-traded funds - KURE is a China Equities fund tracking the MSCI China All Shares Health Care 10/40 Index, while PILL is a Leveraged Equities fund tracking the Dynamic Pharmaceuticals Intellidex Index. Both are passively managed. Over the past 5 years, KURE returned -15.62%/yr vs -12.47%/yr for PILL. At a 0.29 correlation, their price movements are largely independent. KURE charges 0.65%/yr vs 0.98%/yr for PILL.

Performance

KURE vs. PILL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in KraneShares MSCI All China Health Care Index ETF (KURE) and Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, KURE achieves a -8.04% return, which is significantly higher than PILL's -11.70% return.

KURE

• 1D: -0.95%
• 1M: -10.61%
• YTD: -8.04%
• 6M: -13.23%
• 1Y: -0.64%
• 3Y*: -5.12%
• 5Y*: -15.62%
• 10Y*: —

PILL

• 1D: -8.82%
• 1M: -15.56%
• YTD: -11.70%
• 6M: 6.13%
• 1Y: 102.84%
• 3Y*: 12.92%
• 5Y*: -12.47%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

KURE vs. PILL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
KURE KraneShares MSCI All China Health Care Index ETF	-8.04%	24.87%	-17.83%	-17.70%	-25.43%	-16.01%	68.97%	34.30%	-30.07%
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares	-11.70%	75.14%	-7.26%	-12.06%	-43.16%	-37.33%	0.28%	19.26%	-33.54%

Correlation

The correlation between KURE and PILL is 0.28, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.28
Correlation (3Y) Calculated over the trailing 3-year period	0.23
Correlation (5Y) Calculated over the trailing 5-year period	0.26
Correlation (All Time) Calculated using the full available price history since Feb 2, 2018	0.29

KURE vs. PILL - Sectors Allocation Comparison

Sectors	KURE	PILL
Healthcare	99.3%	100.0%
Consumer Defensive	0.7%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Energy	-	-
Financial Services	-	-
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

KURE vs. PILL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

KURE

KURE Risk / Return Rank: 8
KURE Sharpe Ratio Rank: 8
KURE Sortino Ratio Rank: 9
KURE Omega Ratio Rank: 9
KURE Calmar Ratio Rank: 8
KURE Martin Ratio Rank: 8

PILL

PILL Risk / Return Rank: 52
PILL Sharpe Ratio Rank: 48
PILL Sortino Ratio Rank: 44
PILL Omega Ratio Rank: 41
PILL Calmar Ratio Rank: 65
PILL Martin Ratio Rank: 60

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

KURE vs. PILL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for KraneShares MSCI All China Health Care Index ETF (KURE) and Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	KURE	PILL	Difference
Sharpe ratio Return per unit of total volatility	-0.02	1.68	-1.70
Sortino ratio Return per unit of downside risk	0.15	2.26	-2.11
Omega ratio Gain probability vs. loss probability	1.02	1.27	-0.25
Calmar ratio Return relative to maximum drawdown	-0.01	3.28	-3.29
Martin ratio Return relative to average drawdown	-0.02	10.92	-10.94
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

KURE vs. PILL - Sharpe Ratio Comparison

The current KURE Sharpe Ratio is -0.02, which is lower than the PILL Sharpe Ratio of 1.68. The chart below compares the historical Sharpe Ratios of KURE and PILL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	KURE	PILL	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.02	1.68	-1.70
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.49	-0.21	-0.29
Sharpe Ratio (All Time) Calculated using the full available price history	-0.09	-0.13	+0.03

Drawdowns

KURE vs. PILL - Drawdown Comparison

The maximum KURE drawdown since its inception was -68.53%, smaller than the maximum PILL drawdown of -88.76%. Use the drawdown chart below to compare losses from any high point for KURE and PILL.

Drawdown Indicators

	KURE	PILL	Difference
Max Drawdown Largest peak-to-trough decline	-68.53%	-88.76%	+20.23%
Max Drawdown (1Y) Largest decline over 1 year	-25.43%	-33.21%	+7.78%
Max Drawdown (3Y) Largest decline over 3 years	-34.05%	-60.43%	+26.38%
Max Drawdown (5Y) Largest decline over 5 years	-67.94%	-83.38%	+15.44%
Current Drawdown Current decline from peak	-59.96%	-69.74%	+9.78%
Average Drawdown Average peak-to-trough decline	-38.06%	-58.53%	+20.47%
Ulcer Index Depth and duration of drawdowns from previous peaks	13.01%	9.98%	+3.03%

Volatility

KURE vs. PILL - Volatility Comparison

The current volatility for KraneShares MSCI All China Health Care Index ETF (KURE) is 6.84%, while Direxion Daily Pharmaceutical & Medical Bull 3X Shares (PILL) has a volatility of 20.61%. This indicates that KURE experiences smaller price fluctuations and is considered to be less risky than PILL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	KURE	PILL	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.84%	20.61%	-13.77%
Volatility (6M) Calculated over the trailing 6-month period	17.45%	48.73%	-31.28%
Volatility (1Y) Calculated over the trailing 1-year period	26.34%	61.72%	-35.38%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	31.84%	60.41%	-28.57%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	32.38%	63.79%	-31.41%

KURE vs. PILL - Expense Ratio Comparison

KURE has a 0.65% expense ratio, which is lower than PILL's 0.98% expense ratio.

Dividends

KURE vs. PILL - Dividend Comparison

KURE's dividend yield for the trailing twelve months is around 4.56%, more than PILL's 0.71% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017
KURE KraneShares MSCI All China Health Care Index ETF	4.56%	4.19%	1.29%	0.65%	0.05%	14.12%	0.00%	0.25%	0.21%	0.00%
PILL Direxion Daily Pharmaceutical & Medical Bull 3X Shares	0.71%	0.69%	1.28%	1.83%	0.67%	0.00%	0.00%	0.38%	0.91%	0.10%

Frequently Asked Questions

Can I hold both KURE and PILL in my portfolio?

KURE and PILL have a correlation of 0.28, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, KURE or PILL?

PILL has higher volatility (20.61%) compared to KURE (6.84%). In terms of maximum drawdown, KURE dropped -68.53% vs PILL's -88.76%.

Which ETF is better, KURE or PILL?

On 5-year performance, PILL leads with -12.47% vs -15.62% for KURE. On fees, KURE is cheaper at 0.65% per year. On volatility, KURE has been the lower-risk option at 6.84%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, KURE or PILL?

Over the 5-year period, PILL has performed better with a -12.47% return vs -15.62%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, KURE or PILL?

KURE is cheaper with a 0.65% expense ratio, compared with 0.98% for PILL.

Which ETF pays a higher dividend yield, KURE or PILL?

KURE has the higher dividend yield at 4.56%, compared with 0.71% for PILL.

What is the main difference between KURE and PILL?

KURE is categorized as China Equities, while PILL is Leveraged Equities. KURE tracks MSCI China All Shares Health Care 10/40 Index, while PILL tracks Dynamic Pharmaceuticals Intellidex Index. They also come from different issuers: CICC and Direxion. Their fees differ too: 0.65% for KURE and 0.98% for PILL.

Which has better risk-adjusted returns?

PILL currently has the higher Sharpe Ratio (1.68 vs -0.02), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.