JNGLX vs. LTAM.L

Last updated Jun 4, 2026

JNGLX (Janus Henderson Global Life Sciences Fund) and LTAM.L (iShares MSCI EM Latin America UCITS ETF USD (Dist)) are both funds - JNGLX is a Health & Biotech Equities fund managed by Janus Henderson, while LTAM.L is a Latin America Equities fund tracking the MSCI EM Latin America NR USD. Over the past 10 years, JNGLX returned 10.28%/yr vs 7.76%/yr for LTAM.L. At a 0.28 correlation, their price movements are largely independent. JNGLX charges 0.80%/yr vs 0.20%/yr for LTAM.L.

Performance

JNGLX vs. LTAM.L - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Janus Henderson Global Life Sciences Fund (JNGLX) and iShares MSCI EM Latin America UCITS ETF USD (Dist) (LTAM.L). The values are adjusted to include any dividend payments, if applicable.

Different Trading Currencies

JNGLX is traded in USD, while LTAM.L is traded in GBp. To make them comparable, the LTAM.L values have been converted to USD using the latest available exchange rates.

Returns By Period

In the year-to-date period, JNGLX achieves a -3.59% return, which is significantly lower than LTAM.L's 11.01% return. Over the past 10 years, JNGLX has outperformed LTAM.L with an annualized return of 10.28%, while LTAM.L has yielded a comparatively lower 7.76% annualized return.

JNGLX

• 1D: -2.62%
• 1M: -1.53%
• YTD: -3.59%
• 6M: -1.99%
• 1Y: 25.11%
• 3Y*: 9.32%
• 5Y*: 7.03%
• 10Y*: 10.28%

LTAM.L

• 1D: -2.49%
• 1M: -6.39%
• YTD: 11.01%
• 6M: 9.69%
• 1Y: 38.02%
• 3Y*: 14.02%
• 5Y*: 8.73%
• 10Y*: 7.76%

*Multi-year figures are annualized to reflect compound growth (CAGR)

JNGLX vs. LTAM.L - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
JNGLX Janus Henderson Global Life Sciences Fund	-3.59%	24.84%	3.60%	7.51%	-2.69%	6.78%	25.66%	29.20%	4.17%	22.13%
LTAM.L iShares MSCI EM Latin America UCITS ETF USD (Dist)	11.01%	53.94%	-26.89%	32.80%	7.97%	-9.37%	-11.52%	13.83%	-5.83%	21.75%

Correlation

The correlation between JNGLX and LTAM.L is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.24
Correlation (3Y) Calculated over the trailing 3-year period	0.23
Correlation (5Y) Calculated over the trailing 5-year period	0.25
Correlation (10Y) Calculated over the trailing 10-year period	0.28
Correlation (All Time) Calculated using the full available price history since Oct 16, 2007	0.28

Return for Risk

JNGLX vs. LTAM.L — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

JNGLX

JNGLX Risk / Return Rank: 39
JNGLX Sharpe Ratio Rank: 36
JNGLX Sortino Ratio Rank: 37
JNGLX Omega Ratio Rank: 33
JNGLX Calmar Ratio Rank: 48
JNGLX Martin Ratio Rank: 39

LTAM.L

LTAM.L Risk / Return Rank: 64
LTAM.L Sharpe Ratio Rank: 66
LTAM.L Sortino Ratio Rank: 62
LTAM.L Omega Ratio Rank: 61
LTAM.L Calmar Ratio Rank: 71
LTAM.L Martin Ratio Rank: 60

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

JNGLX vs. LTAM.L - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Janus Henderson Global Life Sciences Fund (JNGLX) and iShares MSCI EM Latin America UCITS ETF USD (Dist) (LTAM.L). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	JNGLX	LTAM.L	Difference
Sharpe ratio Return per unit of total volatility	1.73	1.93	-0.20
Sortino ratio Return per unit of downside risk	2.53	2.62	-0.08
Omega ratio Gain probability vs. loss probability	1.30	1.33	-0.02
Calmar ratio Return relative to maximum drawdown	2.65	3.21	-0.56
Martin ratio Return relative to average drawdown	8.47	8.90	-0.44
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

JNGLX vs. LTAM.L - Sharpe Ratio Comparison

The current JNGLX Sharpe Ratio is 1.73, which is comparable to the LTAM.L Sharpe Ratio of 1.93. The chart below compares the historical Sharpe Ratios of JNGLX and LTAM.L, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	JNGLX	LTAM.L	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.73	1.93	-0.20
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.45	0.39	+0.05
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.59	0.30	+0.30
Sharpe Ratio (All Time) Calculated using the full available price history	0.57	0.05	+0.52

Drawdowns

JNGLX vs. LTAM.L - Drawdown Comparison

The maximum JNGLX drawdown since its inception was -59.00%, smaller than the maximum LTAM.L drawdown of -66.21%. Use the drawdown chart below to compare losses from any high point for JNGLX and LTAM.L.

Drawdown Indicators

	JNGLX	LTAM.L	Difference
Max Drawdown Largest peak-to-trough decline	-59.00%	-66.21%	+7.21%
Max Drawdown (1Y) Largest decline over 1 year	-9.68%	-11.78%	+2.10%
Max Drawdown (3Y) Largest decline over 3 years	-21.17%	-27.62%	+6.45%
Max Drawdown (5Y) Largest decline over 5 years	-22.21%	-28.82%	+6.61%
Max Drawdown (10Y) Largest decline over 10 years	-27.37%	-54.91%	+27.54%
Current Drawdown Current decline from peak	-6.49%	-11.78%	+5.29%
Average Drawdown Average peak-to-trough decline	-17.65%	-29.14%	+11.49%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.02%	4.26%	-1.24%

Volatility

JNGLX vs. LTAM.L - Volatility Comparison

The current volatility for Janus Henderson Global Life Sciences Fund (JNGLX) is 4.69%, while iShares MSCI EM Latin America UCITS ETF USD (Dist) (LTAM.L) has a volatility of 6.45%. This indicates that JNGLX experiences smaller price fluctuations and is considered to be less risky than LTAM.L based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	JNGLX	LTAM.L	Difference
Volatility (1M) Calculated over the trailing 1-month period	4.69%	6.45%	-1.76%
Volatility (6M) Calculated over the trailing 6-month period	10.95%	16.64%	-5.69%
Volatility (1Y) Calculated over the trailing 1-year period	14.85%	19.59%	-4.74%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	15.85%	22.27%	-6.42%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	17.38%	26.18%	-8.80%

JNGLX vs. LTAM.L - Expense Ratio Comparison

JNGLX has a 0.80% expense ratio, which is higher than LTAM.L's 0.20% expense ratio.

Dividends

JNGLX vs. LTAM.L - Dividend Comparison

JNGLX's dividend yield for the trailing twelve months is around 4.73%, more than LTAM.L's 3.51% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
JNGLX Janus Henderson Global Life Sciences Fund	4.73%	4.56%	5.84%	4.26%	0.25%	9.85%	7.80%	6.23%	13.32%	0.89%	0.30%	8.81%
LTAM.L iShares MSCI EM Latin America UCITS ETF USD (Dist)	3.51%	3.61%	5.69%	4.33%	6.86%	3.17%	1.82%	2.38%	2.11%	1.52%	1.32%	2.89%

Frequently Asked Questions

Can I hold both JNGLX and LTAM.L in my portfolio?

JNGLX and LTAM.L have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.