ITGR vs. ARGX

Last updated Aug 1, 2026

ITGR (Integer Holdings Corporation) and ARGX (argenx SE) are both stocks. Both are in the Healthcare sector — ITGR in Medical Devices, ARGX in Biotechnology. Over the past 5 years, ITGR returned 4.37%/yr vs 22.91%/yr for ARGX. Their 0.18 correlation means their historical movements had little consistent relationship.

Performance

ITGR vs. ARGX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Integer Holdings Corporation (ITGR) and argenx SE (ARGX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ITGR achieves a 54.55% return, which is significantly higher than ARGX's 1.53% return.

ITGR

• 1D: 20.18%
• 1M: 27.40%
• 6M: 39.55%
• YTD: 54.55%
• 1Y: 13.79%
• 3Y*: 9.38%
• 5Y*: 4.37%
• 10Y*: 18.38%
• ALL TIME*: 7.61%

ARGX

• 1D: -2.15%
• 1M: -9.14%
• 6M: 1.58%
• YTD: 1.53%
• 1Y: 26.72%
• 3Y*: 19.21%
• 5Y*: 22.91%
• 10Y*: —
• ALL TIME*: 52.20%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
ARGX argenx SE	$264.18M	$262.07M	$293.40M
ITGR Integer Holdings Corporation	$66.12M	$55.28M	$49.28M

ITGR vs. ARGX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ITGR Integer Holdings Corporation	54.55%	-40.82%	33.75%	44.73%	-20.01%	5.42%	0.94%	5.47%	68.34%	15.71%
ARGX argenx SE	1.53%	36.74%	61.66%	0.42%	8.18%	19.08%	83.21%	67.09%	52.15%	252.74%

Correlation

The correlation between ITGR and ARGX is -0.01, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	-0.01
Correlation (3Y) Balances recent behavior with more history.	0.13
Correlation (5Y) Shows whether the relationship held over a longer period.	0.17
Correlation (All Time) Calculated using the full available price history since May 18, 2017	0.18

The correlation between ITGR and ARGX shifts across timeframes, from -0.01 (1 year) to 0.18 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ITGR : $4.12B ARGX : $53.10B
EPS ITGR : $4.04 ARGX : $35.23
PE Ratio ITGR : 29.97 ARGX : 24.24
PEG Ratio ITGR : 5.33 ARGX : 0.47
PS Ratio ITGR : 2.29 ARGX : 8.63
PB Ratio ITGR : 2.46 ARGX : 6.53
Total Revenue (TTM) ITGR : $1.86B ARGX : $6.46B
Gross Profit (TTM) ITGR : $491.10M ARGX : $6.96B
EBITDA (TTM) ITGR : $308.94M ARGX : $2.01B

Return for Risk

ITGR vs. ARGX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ITGR

ITGR Risk / Return Rank: 53
ITGR Sharpe Ratio Rank: 55
ITGR Sortino Ratio Rank: 49
ITGR Omega Ratio Rank: 58
ITGR Calmar Ratio Rank: 53
ITGR Martin Ratio Rank: 51

ARGX

ARGX Risk / Return Rank: 69
ARGX Sharpe Ratio Rank: 73
ARGX Sortino Ratio Rank: 69
ARGX Omega Ratio Rank: 67
ARGX Calmar Ratio Rank: 66
ARGX Martin Ratio Rank: 68

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ITGR vs. ARGX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Integer Holdings Corporation (ITGR) and argenx SE (ARGX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ITGR	ARGX	Difference
Sharpe ratio: Return per unit of total volatility	0.25	0.90	-0.65
Sortino ratio: Return per unit of downside risk	0.63	1.45	-0.82
Omega ratio: Gain probability vs. loss probability	1.13	1.17	-0.05
Calmar ratio: Return relative to maximum drawdown	0.28	0.96	-0.69
Martin ratio: Return relative to average drawdown	0.53	2.53	-2.00

ITGR vs. ARGX - Sharpe Ratio Comparison

The current ITGR Sharpe Ratio is 0.25, which is lower than the ARGX Sharpe Ratio of 0.90. The chart below compares the historical Sharpe Ratios of ITGR and ARGX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ITGR vs. ARGX - Drawdown Comparison

The maximum ITGR drawdown since its inception was -67.97%, which is greater than ARGX's maximum drawdown of -38.20%. Use the drawdown chart below to compare losses from any high point for ITGR and ARGX.

Drawdown Indicators

	ITGR	ARGX	Difference
Max Drawdown Largest peak-to-trough decline	-67.97%	-38.20%	-29.77%
Max Drawdown (1Y) Largest decline over 1 year	-42.74%	-28.58%	-14.16%
Max Drawdown (3Y) Largest decline over 3 years	-56.14%	-35.81%	-20.33%
Max Drawdown (5Y) Largest decline over 5 years	-56.14%	-38.20%	-17.94%
Max Drawdown (10Y) Largest decline over 10 years	-56.14%	—	—
Current Drawdown Current decline from peak	-16.04%	-9.14%	-6.90%
Average Drawdown Average peak-to-trough decline	-28.98%	-11.00%	-17.98%
Ulcer Index Depth and duration of drawdowns from previous peaks	22.11%	10.86%	+11.25%

Volatility

ITGR vs. ARGX - Volatility Comparison

Integer Holdings Corporation (ITGR) has a higher volatility of 20.12% compared to argenx SE (ARGX) at 12.26%. This indicates that ITGR's price experiences larger fluctuations and is considered to be riskier than ARGX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ITGR	ARGX	Difference
Volatility (1M) Calculated over the trailing 1-month period	20.12%	12.26%	+7.86%
Volatility (6M) Calculated over the trailing 6-month period	27.57%	25.05%	+2.52%
Volatility (1Y) Calculated over the trailing 1-year period	47.27%	32.75%	+14.52%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	35.81%	38.85%	-3.04%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	38.55%	51.40%	-12.85%

Dividends

ITGR vs. ARGX - Dividend Comparison

Neither ITGR nor ARGX has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ITGR and ARGX in my portfolio?

ITGR and ARGX have a correlation of -0.01, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ITGR or ARGX?

ITGR has higher volatility (20.12%) compared to ARGX (12.26%). In terms of maximum drawdown, ITGR dropped -67.97% vs ARGX's -38.20%.

Which has better risk-adjusted returns?

ARGX currently has the higher Sharpe Ratio (0.90 vs 0.25), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.