IRWD vs. IPSC

Last updated Apr 1, 2026

Compare and contrast key facts about Ironwood Pharmaceuticals, Inc. (IRWD) and Century Therapeutics, Inc. (IPSC).

Performance

IRWD vs. IPSC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Ironwood Pharmaceuticals, Inc. (IRWD) and Century Therapeutics, Inc. (IPSC). The values are adjusted to include any dividend payments, if applicable.

IRWD vs. IPSC - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
IRWD Ironwood Pharmaceuticals, Inc.	4.15%	-23.93%	-61.28%	-7.67%	6.26%	-0.51%
IPSC Century Therapeutics, Inc.	127.18%	-1.50%	-69.58%	-35.28%	-67.65%	-30.53%

Fundamentals

EPS IRWD : $0.21 IPSC : -$0.11
PS Ratio IRWD : 1.34 IPSC : 1.79
Total Revenue (TTM) IRWD : $296.15M IPSC : $109.16M
Gross Profit (TTM) IRWD : $221.01M IPSC : $102.83M
EBITDA (TTM) IRWD : $121.85M IPSC : -$3.89M

Returns By Period

In the year-to-date period, IRWD achieves a 4.15% return, which is significantly lower than IPSC's 127.18% return.

IRWD

• 1D: 8.67%
• 1M: 2.63%
• YTD: 4.15%
• 6M: 167.94%
• 1Y: 138.78%
• 3Y*: -30.64%
• 5Y*: -20.25%
• 10Y*: -10.96%

IPSC

• 1D: 11.33%
• 1M: -2.59%
• YTD: 127.18%
• 6M: 353.82%
• 1Y: 374.79%
• 3Y*: -13.32%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

IRWD vs. IPSC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

IRWD

IRWD Risk / Return Rank: 79
IRWD Sharpe Ratio Rank: 79
IRWD Sortino Ratio Rank: 83
IRWD Omega Ratio Rank: 77
IRWD Calmar Ratio Rank: 81
IRWD Martin Ratio Rank: 75

IPSC

IPSC Risk / Return Rank: 97
IPSC Sharpe Ratio Rank: 98
IPSC Sortino Ratio Rank: 97
IPSC Omega Ratio Rank: 95
IPSC Calmar Ratio Rank: 98
IPSC Martin Ratio Rank: 97

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

IRWD vs. IPSC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Ironwood Pharmaceuticals, Inc. (IRWD) and Century Therapeutics, Inc. (IPSC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	IRWD	IPSC	Difference
Sharpe ratio Return per unit of total volatility	1.19	3.79	-2.60
Sortino ratio Return per unit of downside risk	2.27	4.07	-1.80
Omega ratio Gain probability vs. loss probability	1.27	1.49	-0.23
Calmar ratio Return relative to maximum drawdown	2.42	9.21	-6.79
Martin ratio Return relative to average drawdown	4.56	20.71	-16.15
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

IRWD vs. IPSC - Sharpe Ratio Comparison

The current IRWD Sharpe Ratio is 1.19, which is lower than the IPSC Sharpe Ratio of 3.79. The chart below compares the historical Sharpe Ratios of IRWD and IPSC, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	IRWD	IPSC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.19	3.79	-2.60
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.28	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.18	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.13	-0.45	+0.33

Correlation

The correlation between IRWD and IPSC is 0.23, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

IRWD vs. IPSC - Dividend Comparison

Neither IRWD nor IPSC has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

IRWD vs. IPSC - Drawdown Comparison

The maximum IRWD drawdown since its inception was -97.31%, roughly equal to the maximum IPSC drawdown of -98.78%. Use the drawdown chart below to compare losses from any high point for IRWD and IPSC.

Drawdown Indicators

	IRWD	IPSC	Difference
Max Drawdown Largest peak-to-trough decline	-97.31%	-98.78%	+1.47%
Max Drawdown (1Y) Largest decline over 1 year	-60.67%	-36.98%	-23.69%
Max Drawdown (5Y) Largest decline over 5 years	-96.33%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-97.31%	—	—
Current Drawdown Current decline from peak	-83.34%	-92.92%	+9.58%
Average Drawdown Average peak-to-trough decline	-38.79%	-80.03%	+41.24%
Ulcer Index Depth and duration of drawdowns from previous peaks	32.67%	16.45%	+16.22%

Volatility

IRWD vs. IPSC - Volatility Comparison

The current volatility for Ironwood Pharmaceuticals, Inc. (IRWD) is 21.52%, while Century Therapeutics, Inc. (IPSC) has a volatility of 28.21%. This indicates that IRWD experiences smaller price fluctuations and is considered to be less risky than IPSC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IRWD	IPSC	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.52%	28.21%	-6.69%
Volatility (6M) Calculated over the trailing 6-month period	76.33%	81.70%	-5.37%
Volatility (1Y) Calculated over the trailing 1-year period	117.03%	99.88%	+17.15%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	71.72%	84.63%	-12.91%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	60.32%	84.63%	-24.31%

Financials