IOVA vs. AXSM
Compare and contrast key facts about Iovance Biotherapeutics, Inc. (IOVA) and Axsome Therapeutics, Inc. (AXSM).
Performance
IOVA vs. AXSM - Performance Comparison
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IOVA vs. AXSM - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
IOVA Iovance Biotherapeutics, Inc. | 28.57% | -63.11% | -8.98% | 27.23% | -66.53% | -58.86% | 67.63% | 212.77% | 10.62% | 15.11% |
AXSM Axsome Therapeutics, Inc. | -7.46% | 115.86% | 6.31% | 3.19% | 104.16% | -53.63% | -21.18% | 3,565.25% | -49.64% | -17.04% |
Fundamentals
IOVA:
$1.43B
AXSM:
$8.56B
IOVA:
-$1.06
AXSM:
-$3.66
IOVA:
4.91
AXSM:
13.24
IOVA:
2.04
AXSM:
96.92
IOVA:
$263.50M
AXSM:
$638.50M
IOVA:
$256.22M
AXSM:
$591.02M
IOVA:
-$357.11M
AXSM:
-$168.76M
Returns By Period
In the year-to-date period, IOVA achieves a 28.57% return, which is significantly higher than AXSM's -7.46% return. Over the past 10 years, IOVA has underperformed AXSM with an annualized return of -3.87%, while AXSM has yielded a comparatively higher 34.16% annualized return.
IOVA
- 1D
- 5.72%
- 1M
- -9.07%
- YTD
- 28.57%
- 6M
- 61.75%
- 1Y
- 5.41%
- 3Y*
- -16.87%
- 5Y*
- -35.81%
- 10Y*
- -3.87%
AXSM
- 1D
- 5.31%
- 1M
- 3.13%
- YTD
- -7.46%
- 6M
- 39.17%
- 1Y
- 44.92%
- 3Y*
- 39.94%
- 5Y*
- 24.07%
- 10Y*
- 34.16%
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Return for Risk
IOVA vs. AXSM — Risk / Return Rank
IOVA
AXSM
IOVA vs. AXSM - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Iovance Biotherapeutics, Inc. (IOVA) and Axsome Therapeutics, Inc. (AXSM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| IOVA | AXSM | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 0.05 | 1.11 | -1.06 |
Sortino ratioReturn per unit of downside risk | 0.95 | 1.90 | -0.95 |
Omega ratioGain probability vs. loss probability | 1.13 | 1.23 | -0.11 |
Calmar ratioReturn relative to maximum drawdown | -0.03 | 2.30 | -2.33 |
Martin ratioReturn relative to average drawdown | -0.04 | 5.19 | -5.22 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| IOVA | AXSM | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.05 | 1.11 | -1.06 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.40 | 0.34 | -0.74 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.05 | 0.38 | -0.42 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.14 | 0.36 | -0.49 |
Correlation
The correlation between IOVA and AXSM is 0.28, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.
Dividends
IOVA vs. AXSM - Dividend Comparison
Neither IOVA nor AXSM has paid dividends to shareholders.
Drawdowns
IOVA vs. AXSM - Drawdown Comparison
The maximum IOVA drawdown since its inception was -99.37%, which is greater than AXSM's maximum drawdown of -86.65%. Use the drawdown chart below to compare losses from any high point for IOVA and AXSM.
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Drawdown Indicators
| IOVA | AXSM | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.37% | -86.65% | -12.72% |
Max Drawdown (1Y)Largest decline over 1 year | -54.41% | -18.50% | -35.91% |
Max Drawdown (5Y)Largest decline over 5 years | -94.98% | -72.91% | -22.07% |
Max Drawdown (10Y)Largest decline over 10 years | -96.84% | -83.92% | -12.92% |
Current DrawdownCurrent decline from peak | -97.79% | -10.62% | -87.17% |
Average DrawdownAverage peak-to-trough decline | -84.00% | -40.21% | -43.79% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 37.72% | 8.21% | +29.51% |
Volatility
IOVA vs. AXSM - Volatility Comparison
Iovance Biotherapeutics, Inc. (IOVA) has a higher volatility of 30.93% compared to Axsome Therapeutics, Inc. (AXSM) at 11.02%. This indicates that IOVA's price experiences larger fluctuations and is considered to be riskier than AXSM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| IOVA | AXSM | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 30.93% | 11.02% | +19.91% |
Volatility (6M)Calculated over the trailing 6-month period | 65.62% | 30.60% | +35.02% |
Volatility (1Y)Calculated over the trailing 1-year period | 112.34% | 40.86% | +71.48% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 90.77% | 70.52% | +20.25% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 81.92% | 90.95% | -9.03% |
Financials
IOVA vs. AXSM - Financials Comparison
This section allows you to compare key financial metrics between Iovance Biotherapeutics, Inc. and Axsome Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities