- ISIN
- US4622601007
- CUSIP
- 462260100
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- Oct 15, 2010
Highlights
- Market Cap
- $1.70B
- Enterprise Value
- $1.55B
- EPS (TTM)
- -$0.93
- Total Revenue (TTM)
- $285.61M
- Gross Profit (TTM)
- $327.04M
- EBITDA (TTM)
- -$325.45M
- Year Range
- $1.66 - $5.63
- Target Price
- $2.00
- ROA (TTM)
- -38.23%
- ROE (TTM)
- -49.03%
Share Price Chart
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Performance
IOVA Performance Chart
Iovance Biotherapeutics, Inc. (IOVA) is up 48.7% since the beginning of the year. At $4 per share, IOVA is trading 27.9% below its 52-week high of $6. Investors who bought $1,000 worth of IOVA shares 5 years ago would now be looking at an investment worth $164.
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Returns By Period
Iovance Biotherapeutics, Inc. (IOVA) has returned 48.72% so far this year and 105.05% over the past 12 months. Over the last ten years, IOVA has returned -6.39% per year, falling short of the S&P 500 Index benchmark, which averaged 13.88% annually.
Iovance Biotherapeutics, Inc.
- 1D
- 3.84%
- 1M
- -1.22%
- YTD
- 48.72%
- 6M
- 46.04%
- 1Y
- 105.05%
- 3Y*
- -20.47%
- 5Y*
- -30.33%
- 10Y*
- -6.39%
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
IOVA Monthly Returns History
Based on dividend-adjusted daily data since Oct 15, 2010, IOVA's average daily return is +0.30%, while the average monthly return is +2.39%. At this rate, an investment would double in approximately 2.4 years.
Historically, 44% of months were positive and 56% were negative. The best month was Jul 2013 with a return of +250.0%, while the worst month was Apr 2013 at -66.7%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 6 months.
On a daily basis, IOVA closed higher 43% of trading days. The best single day was May 3, 2013 with a return of +200.0%, while the worst single day was May 7, 2013 at -83.3%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -6.59% | 51.37% | -9.07% | -4.27% | 22.02% | -0.98% | 48.72% | ||||||
| 2025 | -20.95% | -27.61% | -21.37% | 7.81% | -51.25% | -1.71% | 49.42% | -13.23% | -2.69% | -9.22% | 25.38% | 10.53% | -63.11% |
| 2024 | -4.92% | 105.82% | -6.85% | -20.51% | -24.62% | -9.68% | 8.85% | 33.56% | -19.47% | 11.18% | -10.73% | -20.60% | -8.98% |
| 2023 | 24.57% | -8.42% | -16.19% | -7.69% | 54.96% | -19.45% | 3.13% | -16.80% | -24.67% | -16.04% | 58.90% | 33.94% | 27.23% |
| 2022 | -12.78% | -5.89% | 6.25% | -9.01% | -55.45% | 63.56% | 5.53% | -7.98% | -10.63% | -2.51% | -31.48% | -0.16% | -66.53% |
| 2021 | -5.52% | -14.92% | -15.12% | -0.69% | -40.94% | 40.12% | -14.41% | 8.08% | 2.45% | -1.42% | -22.99% | 1.98% | -58.86% |
Benchmark Metrics
Iovance Biotherapeutics, Inc. has an annualized alpha of 81.75%, beta of 1.27, and R2 of 0.02 versus S&P 500 Index. Calculated based on daily prices since October 15, 2010.
- This stock participated in 174.71% of S&P 500 Index downside but only 30.76% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.02 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 81.75%
- Beta
- 1.27
- R²
- 0.02
- Upside Capture
- 30.76%
- Downside Capture
- 174.71%
Return for Risk
Risk / Return Rank
IOVA ranks 74 for risk / return — better than 74% of stocks on our site. You're getting solid returns for the risk taken. A good sign, especially for investors who want growth without excessive volatility.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for Iovance Biotherapeutics, Inc. (IOVA) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| IOVA | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.99 | ||
| Sortino ratioReturn per unit of downside risk | -0.62 | ||
| Omega ratioGain probability vs. loss probability | 1.24 | 1.37 | -0.12 |
| Calmar ratioReturn relative to maximum drawdown | 1.94 | 2.78 | -0.84 |
| Martin ratioReturn relative to average drawdown | 3.05 | 12.44 | -9.39 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Iovance Biotherapeutics, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Iovance Biotherapeutics, Inc. was 99.37%, occurring on Apr 12, 2013. The portfolio has not yet recovered.
The current Iovance Biotherapeutics, Inc. drawdown is 97.45%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2013 bear market2013 | -99.37%Apr 2013 | 1y 10mo | — | 15y 19dJun 2011 - now |
2010 correction2010 | -13.51%Nov 2010 | 3d | 12d | 15dNov 2010 - Dec 2010 |
2011 correction2011 | -12.70%Mar 2011 | 5d | 1mo 14d | 1mo 19dMar 2011 - Apr 2011 |
2010 pullback2010 | -9.09%Oct 2010 | 3d | 7d | 10dOct 2010 - Oct 2010 |
2010 pullback2010 | -7.56%Dec 2010 | 2d | 6d | 8dDec 2010 - Dec 2010 |
Drawdown Indicators
| IOVA | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.37% | -56.78% | -42.59% |
Max Drawdown (1Y)Largest decline over 1 year | -54.41% | -9.10% | -45.31% |
Max Drawdown (3Y)Largest decline over 3 years | -90.50% | -18.90% | -71.60% |
Max Drawdown (5Y)Largest decline over 5 years | -93.99% | -25.43% | -68.56% |
Max Drawdown (10Y)Largest decline over 10 years | -96.84% | -33.92% | -62.92% |
Current DrawdownCurrent decline from peak | -97.45% | -1.80% | -95.65% |
Average DrawdownAverage peak-to-trough decline | -84.18% | -10.71% | -73.47% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 34.61% | 2.03% | +32.58% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Iovance Biotherapeutics, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Iovance Biotherapeutics, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for IOVA relative to other companies in the Biotechnology industry. Currently, IOVA has a P/S ratio of 5.4. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for IOVA in comparison with other companies in the Biotechnology industry. Currently, IOVA has a P/B value of 2.4. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.
Income Statement
| TTM | |
|---|---|
Revenue | — |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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