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ISIN
US4622601007
CUSIP
462260100
IPO Date
Oct 15, 2010

Highlights

Market Cap
$1.70B
Enterprise Value
$1.55B
EPS (TTM)
-$0.93
Total Revenue (TTM)
$285.61M
Gross Profit (TTM)
$327.04M
EBITDA (TTM)
-$325.45M
Year Range
$1.66 - $5.63
Target Price
$2.00
ROA (TTM)
-38.23%
ROE (TTM)
-49.03%

Share Price Chart


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Performance

IOVA Performance Chart

Iovance Biotherapeutics, Inc. (IOVA) is up 48.7% since the beginning of the year. At $4 per share, IOVA is trading 27.9% below its 52-week high of $6. Investors who bought $1,000 worth of IOVA shares 5 years ago would now be looking at an investment worth $164.


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S&P 500 Index

Returns By Period

Iovance Biotherapeutics, Inc. (IOVA) has returned 48.72% so far this year and 105.05% over the past 12 months. Over the last ten years, IOVA has returned -6.39% per year, falling short of the S&P 500 Index benchmark, which averaged 13.88% annually.


Iovance Biotherapeutics, Inc.

1D
3.84%
1M
-1.22%
YTD
48.72%
6M
46.04%
1Y
105.05%
3Y*
-20.47%
5Y*
-30.33%
10Y*
-6.39%

Benchmark (S&P 500 Index)

1D
-0.37%
1M
-0.01%
YTD
9.16%
6M
8.64%
1Y
25.22%
3Y*
19.78%
5Y*
11.99%
10Y*
13.88%
*Multi-year figures are annualized to reflect compound growth (CAGR)

IOVA Monthly Returns History

Based on dividend-adjusted daily data since Oct 15, 2010, IOVA's average daily return is +0.30%, while the average monthly return is +2.39%. At this rate, an investment would double in approximately 2.4 years.

Historically, 44% of months were positive and 56% were negative. The best month was Jul 2013 with a return of +250.0%, while the worst month was Apr 2013 at -66.7%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 6 months.

On a daily basis, IOVA closed higher 43% of trading days. The best single day was May 3, 2013 with a return of +200.0%, while the worst single day was May 7, 2013 at -83.3%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-6.59%51.37%-9.07%-4.27%22.02%-0.98%48.72%
2025-20.95%-27.61%-21.37%7.81%-51.25%-1.71%49.42%-13.23%-2.69%-9.22%25.38%10.53%-63.11%
2024-4.92%105.82%-6.85%-20.51%-24.62%-9.68%8.85%33.56%-19.47%11.18%-10.73%-20.60%-8.98%
202324.57%-8.42%-16.19%-7.69%54.96%-19.45%3.13%-16.80%-24.67%-16.04%58.90%33.94%27.23%
2022-12.78%-5.89%6.25%-9.01%-55.45%63.56%5.53%-7.98%-10.63%-2.51%-31.48%-0.16%-66.53%
2021-5.52%-14.92%-15.12%-0.69%-40.94%40.12%-14.41%8.08%2.45%-1.42%-22.99%1.98%-58.86%

Benchmark Metrics

Iovance Biotherapeutics, Inc. has an annualized alpha of 81.75%, beta of 1.27, and R2 of 0.02 versus S&P 500 Index. Calculated based on daily prices since October 15, 2010.

  • This stock participated in 174.71% of S&P 500 Index downside but only 30.76% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.02 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
81.75%
Beta
1.27
0.02
Upside Capture
30.76%
Downside Capture
174.71%

Return for Risk

Risk / Return Rank

IOVA ranks 74 for risk / return — better than 74% of stocks on our site. You're getting solid returns for the risk taken. A good sign, especially for investors who want growth without excessive volatility.


IOVA Risk / Return Rank: 7474
Overall Rank
IOVA Sharpe Ratio Rank: 7474
Sharpe Ratio Rank
IOVA Sortino Ratio Rank: 7979
Sortino Ratio Rank
IOVA Omega Ratio Rank: 7474
Omega Ratio Rank
IOVA Calmar Ratio Rank: 7575
Calmar Ratio Rank
IOVA Martin Ratio Rank: 6868
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Iovance Biotherapeutics, Inc. (IOVA) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


IOVABenchmarkDifference
Sharpe ratioReturn per unit of total volatility

-0.99

Sortino ratioReturn per unit of downside risk

-0.62

Omega ratioGain probability vs. loss probability

1.24

1.37

-0.12

Calmar ratioReturn relative to maximum drawdown

1.94

2.78

-0.84

Martin ratioReturn relative to average drawdown

3.05

12.44

-9.39

Dividends

Dividend History


Iovance Biotherapeutics, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Iovance Biotherapeutics, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Iovance Biotherapeutics, Inc. was 99.37%, occurring on Apr 12, 2013. The portfolio has not yet recovered.

The current Iovance Biotherapeutics, Inc. drawdown is 97.45%.


Related event

Drawdown

Fall

Recovery

Underwater

2013 bear market2013
-99.37%Apr 2013
1y 10mo
15y 19dJun 2011 - now
2010 correction2010
-13.51%Nov 2010
3d12d
15dNov 2010 - Dec 2010
2011 correction2011
-12.70%Mar 2011
5d1mo 14d
1mo 19dMar 2011 - Apr 2011
2010 pullback2010
-9.09%Oct 2010
3d7d
10dOct 2010 - Oct 2010
2010 pullback2010
-7.56%Dec 2010
2d6d
8dDec 2010 - Dec 2010

Drawdown Indicators


IOVABenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-99.37%

-56.78%

-42.59%

Max Drawdown (1Y)

Largest decline over 1 year

-54.41%

-9.10%

-45.31%

Max Drawdown (3Y)

Largest decline over 3 years

-90.50%

-18.90%

-71.60%

Max Drawdown (5Y)

Largest decline over 5 years

-93.99%

-25.43%

-68.56%

Max Drawdown (10Y)

Largest decline over 10 years

-96.84%

-33.92%

-62.92%

Current Drawdown

Current decline from peak

-97.45%

-1.80%

-95.65%

Average Drawdown

Average peak-to-trough decline

-84.18%

-10.71%

-73.47%

Ulcer Index

Depth and duration of drawdowns from previous peaks

34.61%

2.03%

+32.58%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Iovance Biotherapeutics, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Iovance Biotherapeutics, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for IOVA relative to other companies in the Biotechnology industry. Currently, IOVA has a P/S ratio of 5.4. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for IOVA in comparison with other companies in the Biotechnology industry. Currently, IOVA has a P/B value of 2.4. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
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