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Iovance Biotherapeutics, Inc. (IOVA)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
US4622601007
CUSIP
462260100
IPO Date
Oct 15, 2010

Highlights

Market Cap
$1.43B
Enterprise Value
$1.32B
EPS (TTM)
-$1.06
Total Revenue (TTM)
$263.50M
Gross Profit (TTM)
$256.22M
EBITDA (TTM)
-$357.11M
Year Range
$1.64 - $5.63
Target Price
$2.00
ROA (TTM)
-42.82%
ROE (TTM)
-55.97%

Share Price Chart


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Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Iovance Biotherapeutics, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

Iovance Biotherapeutics, Inc. (IOVA) has returned 28.57% so far this year and 5.41% over the past 12 months. Over the last ten years, IOVA has returned -3.87% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.


Iovance Biotherapeutics, Inc.

1D
5.72%
1M
-9.07%
YTD
28.57%
6M
61.75%
1Y
5.41%
3Y*
-16.87%
5Y*
-35.81%
10Y*
-3.87%

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Oct 15, 2010, IOVA's average daily return is +0.30%, while the average monthly return is +2.31%. At this rate, your investment would double in approximately 2.5 years.

Historically, 44% of months were positive and 56% were negative. The best month was Jul 2013 with a return of +250.0%, while the worst month was Apr 2013 at -66.7%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 6 months.

On a daily basis, IOVA closed higher 43% of trading days. The best single day was May 3, 2013 with a return of +200.0%, while the worst single day was May 7, 2013 at -83.3%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-6.59%51.37%-9.07%28.57%
2025-20.95%-27.61%-21.37%7.81%-51.25%-1.71%49.42%-13.23%-2.69%-9.22%25.38%10.53%-63.11%
2024-4.92%105.82%-6.85%-20.51%-24.62%-9.68%8.85%33.56%-19.47%11.18%-10.73%-20.60%-8.98%
202324.57%-8.42%-16.19%-7.69%54.96%-19.45%3.13%-16.80%-24.67%-16.04%58.90%33.94%27.23%
2022-12.78%-5.89%6.25%-9.01%-55.45%63.56%5.53%-7.98%-10.63%-2.51%-31.48%-0.16%-66.53%
2021-5.52%-14.92%-15.12%-0.69%-40.94%40.12%-14.41%8.08%2.45%-1.42%-22.99%1.98%-58.86%

Benchmark Metrics

Iovance Biotherapeutics, Inc. has an annualized alpha of 82.28%, beta of 1.27, and R² of 0.02 versus S&P 500 Index. Calculated based on daily prices since October 18, 2010.

  • This stock participated in 174.90% of S&P 500 Index downside but only 27.26% of its upside — more exposed to losses than it benefited from rallies.
  • R² of 0.02 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
82.28%
Beta
1.27
0.02
Upside Capture
27.26%
Downside Capture
174.90%

Return for Risk

Risk / Return Rank

IOVA ranks 45 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


IOVA Risk / Return Rank: 4545
Overall Rank
IOVA Sharpe Ratio Rank: 4141
Sharpe Ratio Rank
IOVA Sortino Ratio Rank: 5353
Sortino Ratio Rank
IOVA Omega Ratio Rank: 5353
Omega Ratio Rank
IOVA Calmar Ratio Rank: 4040
Calmar Ratio Rank
IOVA Martin Ratio Rank: 3939
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Iovance Biotherapeutics, Inc. (IOVA) and compare them to a chosen benchmark (S&P 500 Index).


IOVABenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.05

0.90

-0.85

Sortino ratio

Return per unit of downside risk

0.95

1.39

-0.43

Omega ratio

Gain probability vs. loss probability

1.13

1.21

-0.09

Calmar ratio

Return relative to maximum drawdown

-0.03

1.40

-1.42

Martin ratio

Return relative to average drawdown

-0.04

6.61

-6.64

Explore IOVA risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Iovance Biotherapeutics, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Iovance Biotherapeutics, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Iovance Biotherapeutics, Inc. was 99.37%, occurring on Apr 12, 2013. The portfolio has not yet recovered.

The current Iovance Biotherapeutics, Inc. drawdown is 97.79%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-99.37%Jun 8, 2011464Apr 12, 2013
-13.51%Nov 16, 20104Nov 19, 20107Dec 1, 201011
-12.7%Mar 9, 20114Mar 14, 201133Apr 29, 201137
-9.09%Oct 19, 20104Oct 22, 20105Oct 29, 20109
-7.56%Dec 6, 20103Dec 8, 20104Dec 14, 20107

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Iovance Biotherapeutics, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Iovance Biotherapeutics, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for IOVA relative to other companies in the Biotechnology industry. Currently, IOVA has a P/S ratio of 4.9. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for IOVA in comparison with other companies in the Biotechnology industry. Currently, IOVA has a P/B value of 2.0. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items