IDNA vs. HEAL

Last updated Aug 3, 2026

IDNA (iShares Genomics Immunology and Healthcare ETF) and HEAL (Global X HealthTech ETF) are both Health & Biotech Equities funds - IDNA tracks the NYSE FactSet Global Genomics and Immuno Biopharma Index (USD) (Net) while HEAL tracks the Global X HealthTech Index. Both are passively managed. Over the past 5 years, IDNA returned -7.52%/yr vs -13.37%/yr for HEAL. Their 0.70 correlation means they have sometimes moved together and sometimes differently. IDNA charges 0.47%/yr vs 0.50%/yr for HEAL.

Performance

IDNA vs. HEAL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in iShares Genomics Immunology and Healthcare ETF (IDNA) and Global X HealthTech ETF (HEAL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, IDNA achieves a 23.97% return, which is significantly higher than HEAL's -7.90% return.

IDNA

• 1D: -1.40%
• 1M: -7.39%
• 6M: 13.88%
• YTD: 23.97%
• 1Y: 54.41%
• 3Y*: 12.75%
• 5Y*: -7.52%
• 10Y*: —
• ALL TIME*: 4.74%

HEAL

• 1D: 0.07%
• 1M: -7.11%
• 6M: -5.44%
• YTD: -7.90%
• 1Y: -12.88%
• 3Y*: -8.61%
• 5Y*: -13.37%
• 10Y*: —
• ALL TIME*: -9.61%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
HEAL Global X HealthTech ETF	$245.64K	$221.54K	$214.19K
IDNA iShares Genomics Immunology and Healthcare ETF	$842.73K	$1.44M	$1.52M

IDNA vs. HEAL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
IDNA iShares Genomics Immunology and Healthcare ETF	23.97%	17.26%	-0.72%	-7.63%	-42.28%	-3.98%	21.46%
HEAL Global X HealthTech ETF	-7.90%	-0.62%	-2.87%	-12.61%	-29.99%	-14.21%	16.89%

Correlation

The correlation between IDNA and HEAL is 0.55, which is moderate. They have sometimes moved together and sometimes differently, sharing some price drivers without tracking each other closely.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.55
Correlation (3Y) Balances recent behavior with more history.	0.60
Correlation (5Y) Shows whether the relationship held over a longer period.	0.70
Correlation (All Time) Calculated using the full available price history since Jul 30, 2020	0.70

The correlation between IDNA and HEAL shifts across timeframes, from 0.55 (1 year) to 0.70 (all time), reflecting how their relationship changes across market environments.

IDNA vs. HEAL - Sectors Allocation Comparison

Sectors	IDNA	HEAL
Healthcare	100.0%	94.1%
Industrials	0.3%	-
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	-
Real Estate	-	-
Technology	-	5.3%
Utilities	-	-

Return for Risk

IDNA vs. HEAL — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

IDNA

IDNA Risk / Return Rank: 88
IDNA Sharpe Ratio Rank: 89
IDNA Sortino Ratio Rank: 88
IDNA Omega Ratio Rank: 81
IDNA Calmar Ratio Rank: 94
IDNA Martin Ratio Rank: 88

HEAL

HEAL Risk / Return Rank: 5
HEAL Sharpe Ratio Rank: 4
HEAL Sortino Ratio Rank: 4
HEAL Omega Ratio Rank: 4
HEAL Calmar Ratio Rank: 6
HEAL Martin Ratio Rank: 6

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

IDNA vs. HEAL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares Genomics Immunology and Healthcare ETF (IDNA) and Global X HealthTech ETF (HEAL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	IDNA	HEAL	Difference
Sharpe ratio: Return per unit of total volatility	2.17	-0.61	+2.77
Sortino ratio: Return per unit of downside risk	3.01	-0.76	+3.77
Omega ratio: Gain probability vs. loss probability	1.34	0.92	+0.42
Calmar ratio: Return relative to maximum drawdown	5.06	-0.45	+5.51
Martin ratio: Return relative to average drawdown	13.37	-0.82	+14.19

IDNA vs. HEAL - Sharpe Ratio Comparison

The current IDNA Sharpe Ratio is 2.17, which is higher than the HEAL Sharpe Ratio of -0.61. The chart below compares the historical Sharpe Ratios of IDNA and HEAL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

IDNA vs. HEAL - Drawdown Comparison

The maximum IDNA drawdown since its inception was -68.26%, roughly equal to the maximum HEAL drawdown of -65.76%. Use the drawdown chart below to compare losses from any high point for IDNA and HEAL.

Drawdown Indicators

	IDNA	HEAL	Difference
Max Drawdown Largest peak-to-trough decline	-68.26%	-65.76%	-2.50%
Max Drawdown (1Y) Largest decline over 1 year	-10.66%	-30.71%	+20.05%
Max Drawdown (3Y) Largest decline over 3 years	-29.46%	-34.56%	+5.10%
Max Drawdown (5Y) Largest decline over 5 years	-68.26%	-59.14%	-9.12%
Current Drawdown Current decline from peak	-38.88%	-60.24%	+21.36%
Average Drawdown Average peak-to-trough decline	-36.30%	-43.48%	+7.18%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.03%	16.87%	-12.84%

Volatility

IDNA vs. HEAL - Volatility Comparison

iShares Genomics Immunology and Healthcare ETF (IDNA) has a higher volatility of 7.04% compared to Global X HealthTech ETF (HEAL) at 6.34%. This indicates that IDNA's price experiences larger fluctuations and is considered to be riskier than HEAL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	IDNA	HEAL	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.04%	6.34%	+0.70%
Volatility (6M) Calculated over the trailing 6-month period	18.24%	17.24%	+1.00%
Volatility (1Y) Calculated over the trailing 1-year period	25.03%	22.70%	+2.33%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	28.50%	26.63%	+1.87%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	29.44%	26.25%	+3.19%

IDNA vs. HEAL - Expense Ratio Comparison

IDNA has a 0.47% expense ratio, which is lower than HEAL's 0.50% expense ratio.

Dividends

IDNA vs. HEAL - Dividend Comparison

IDNA's dividend yield for the trailing twelve months is around 0.87%, more than HEAL's 0.27% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019
HEAL Global X HealthTech ETF	0.27%	0.33%	0.00%	0.00%	0.00%	0.00%	0.03%	0.00%
IDNA iShares Genomics Immunology and Healthcare ETF	0.87%	1.18%	0.98%	1.04%	0.54%	0.70%	0.26%	0.80%

Frequently Asked Questions

Can I hold both IDNA and HEAL in my portfolio?

IDNA and HEAL have a correlation of 0.55, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, IDNA or HEAL?

IDNA has higher volatility (7.04%) compared to HEAL (6.34%). In terms of maximum drawdown, IDNA dropped -68.26% vs HEAL's -65.76%.

Which ETF is better, IDNA or HEAL?

On 5-year performance, IDNA leads with -7.52% vs -13.37% for HEAL. On fees, IDNA is cheaper at 0.47% per year. On volatility, HEAL has been the lower-risk option at 6.34%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, IDNA or HEAL?

Over the 5-year period, IDNA has performed better with a -7.52% return vs -13.37%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, IDNA or HEAL?

IDNA is cheaper with a 0.47% expense ratio, compared with 0.50% for HEAL.

Which ETF pays a higher dividend yield, IDNA or HEAL?

IDNA has the higher dividend yield at 0.87%, compared with 0.27% for HEAL.

What is the main difference between IDNA and HEAL?

IDNA tracks NYSE FactSet Global Genomics and Immuno Biopharma Index (USD) (Net), while HEAL tracks Global X HealthTech Index. They also come from different issuers: iShares and Global X. Their fees differ too: 0.47% for IDNA and 0.50% for HEAL.

Which has better risk-adjusted returns?

IDNA currently has the higher Sharpe Ratio (2.17 vs -0.61), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.