IBRN vs. USO
IBRN (iShares Neuroscience and Healthcare ETF) and USO (United States Oil Fund LP) are both exchange-traded funds - IBRN is a Health & Biotech Equities fund tracking the NYSE FactSet Global Neuro Biopharma and MedTech Index, while USO is a Oil & Gas fund tracking the Front Month Light Sweet Crude Oil. Both are passively managed. Over the past 3 years, IBRN returned 11.10%/yr vs 28.86%/yr for USO. At a correlation of -0.03, they often move in opposite directions. IBRN charges 0.47%/yr vs 0.86%/yr for USO.
Performance
IBRN vs. USO - Performance Comparison
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Returns By Period
In the year-to-date period, IBRN achieves a 4.62% return, which is significantly lower than USO's 98.48% return.
IBRN
- 1D
- -4.52%
- 1M
- -1.90%
- YTD
- 4.62%
- 6M
- 12.73%
- 1Y
- 52.57%
- 3Y*
- 11.10%
- 5Y*
- —
- 10Y*
- —
USO
- 1D
- 1.31%
- 1M
- -3.87%
- YTD
- 98.48%
- 6M
- 95.54%
- 1Y
- 97.37%
- 3Y*
- 28.86%
- 5Y*
- 23.92%
- 10Y*
- 3.80%
IBRN vs. USO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
IBRN iShares Neuroscience and Healthcare ETF | 4.62% | 28.49% | -2.78% | 0.92% | 5.85% |
USO United States Oil Fund LP | 98.48% | -8.46% | 13.35% | -4.94% | -7.57% |
Correlation
The correlation between IBRN and USO is -0.30, meaning they tend to move in opposite directions. This is especially valuable for risk management - when one declines, the other has historically tended to hold steady or rise.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | -0.30 |
Correlation (3Y) Calculated over the trailing 3-year period | -0.11 |
Correlation (All Time) Calculated using the full available price history since Aug 29, 2022 | -0.03 |
Over the past year, the inverse relationship between IBRN and USO has strengthened: their correlation has moved from -0.03 to -0.30, meaning they now move in opposite directions more often than their long-term average.
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Return for Risk
IBRN vs. USO — Risk / Return Rank
IBRN
USO
IBRN vs. USO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Neuroscience and Healthcare ETF (IBRN) and United States Oil Fund LP (USO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| IBRN | USO | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 2.09 | 2.22 | -0.13 |
Sortino ratioReturn per unit of downside risk | 2.94 | 2.81 | +0.12 |
Omega ratioGain probability vs. loss probability | 1.34 | 1.37 | -0.04 |
Calmar ratioReturn relative to maximum drawdown | 6.30 | 5.12 | +1.18 |
Martin ratioReturn relative to average drawdown | 15.59 | 9.66 | +5.93 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| IBRN | USO | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 2.09 | 2.22 | -0.13 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | — | 0.67 | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.10 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.37 | -0.18 | +0.55 |
Drawdowns
IBRN vs. USO - Drawdown Comparison
The maximum IBRN drawdown since its inception was -35.38%, smaller than the maximum USO drawdown of -98.19%. Use the drawdown chart below to compare losses from any high point for IBRN and USO.
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Drawdown Indicators
| IBRN | USO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -35.38% | -98.19% | +62.81% |
Max Drawdown (1Y)Largest decline over 1 year | -8.80% | -20.39% | +11.59% |
Max Drawdown (3Y)Largest decline over 3 years | -35.38% | -26.05% | -9.33% |
Max Drawdown (5Y)Largest decline over 5 years | — | -36.23% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -86.75% | — |
Current DrawdownCurrent decline from peak | -6.28% | -85.39% | +79.11% |
Average DrawdownAverage peak-to-trough decline | -9.83% | -75.30% | +65.47% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 3.56% | 10.81% | -7.25% |
Volatility
IBRN vs. USO - Volatility Comparison
The current volatility for iShares Neuroscience and Healthcare ETF (IBRN) is 7.66%, while United States Oil Fund LP (USO) has a volatility of 15.03%. This indicates that IBRN experiences smaller price fluctuations and is considered to be less risky than USO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| IBRN | USO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.66% | 15.03% | -7.37% |
Volatility (6M)Calculated over the trailing 6-month period | 19.29% | 38.18% | -18.89% |
Volatility (1Y)Calculated over the trailing 1-year period | 25.38% | 44.26% | -18.88% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 25.32% | 36.04% | -10.72% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 25.32% | 39.00% | -13.68% |
IBRN vs. USO - Expense Ratio Comparison
IBRN has a 0.47% expense ratio, which is lower than USO's 0.86% expense ratio.
Dividends
IBRN vs. USO - Dividend Comparison
IBRN's dividend yield for the trailing twelve months is around 0.95%, while USO has not paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 |
|---|---|---|---|---|
IBRN iShares Neuroscience and Healthcare ETF | 0.95% | 0.99% | 0.40% | 0.06% |
USO United States Oil Fund LP | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
IBRN and USO have a correlation of -0.30, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
USO has higher volatility (15.03%) compared to IBRN (7.66%). In terms of maximum drawdown, IBRN dropped -35.38% vs USO's -98.19%.
On 3-year performance, USO leads with 28.86% vs 11.10% for IBRN. On fees, IBRN is cheaper at 0.47% per year. On volatility, IBRN has been the lower-risk option at 7.66%. The better choice depends on whether you care most about return, fees, risk, or income.
Over the 3-year period, USO has performed better with a 28.86% return vs 11.10%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.
IBRN is cheaper with a 0.47% expense ratio, compared with 0.86% for USO.
IBRN has the higher dividend yield at 0.95%, compared with 0.00% for USO.
IBRN is categorized as Health & Biotech Equities, while USO is Oil & Gas. IBRN tracks NYSE FactSet Global Neuro Biopharma and MedTech Index, while USO tracks Front Month Light Sweet Crude Oil. They also come from different issuers: iShares and USCF. Their fees differ too: 0.47% for IBRN and 0.86% for USO.
USO currently has the higher Sharpe Ratio (2.22 vs 2.09), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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