HURA vs. ACRV

Last updated Jun 3, 2026

HURA (TuHURA Biosciences, Inc.) and ACRV (Acrivon Therapeutics Inc. Common Stock) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 3 years, HURA returned -73.82%/yr vs -49.75%/yr for ACRV. At a 0.09 correlation, their price movements are largely independent.

Performance

HURA vs. ACRV - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in TuHURA Biosciences, Inc. (HURA) and Acrivon Therapeutics Inc. Common Stock (ACRV). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, HURA achieves a 188.09% return, which is significantly higher than ACRV's -34.85% return.

HURA

• 1D: -2.68%
• 1M: -6.44%
• YTD: 188.09%
• 6M: 20.44%
• 1Y: -30.13%
• 3Y*: -73.82%
• 5Y*: -75.99%
• 10Y*: -66.45%

ACRV

• 1D: 0.64%
• 1M: -24.88%
• YTD: -34.85%
• 6M: -28.64%
• 1Y: 41.44%
• 3Y*: -49.75%
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

HURA vs. ACRV - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
HURA TuHURA Biosciences, Inc.	188.09%	-81.50%	-31.10%	-97.54%	73.12%
ACRV Acrivon Therapeutics Inc. Common Stock	-34.85%	-59.97%	22.36%	-57.29%	-30.77%

Correlation

The correlation between HURA and ACRV is 0.19, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.19
Correlation (3Y) Calculated over the trailing 3-year period	0.11
Correlation (All Time) Calculated using the full available price history since Nov 16, 2022	0.09

The correlation between HURA and ACRV shifts across timeframes, from 0.09 (all time) to 0.19 (1 year), reflecting how their relationship changes across market environments.

Fundamentals

EPS HURA : -$0.62 ACRV : -$2.00
Total Revenue (TTM) HURA : $0.00 ACRV : $0.00
Gross Profit (TTM) HURA : -$17.64K ACRV : $311.00K
EBITDA (TTM) HURA : -$28.68M ACRV : -$84.65M

Return for Risk

HURA vs. ACRV — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

HURA

HURA Risk / Return Rank: 35
HURA Sharpe Ratio Rank: 30
HURA Sortino Ratio Rank: 45
HURA Omega Ratio Rank: 43
HURA Calmar Ratio Rank: 30
HURA Martin Ratio Rank: 28

ACRV

ACRV Risk / Return Rank: 58
ACRV Sharpe Ratio Rank: 56
ACRV Sortino Ratio Rank: 61
ACRV Omega Ratio Rank: 60
ACRV Calmar Ratio Rank: 58
ACRV Martin Ratio Rank: 57

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

HURA vs. ACRV - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for TuHURA Biosciences, Inc. (HURA) and Acrivon Therapeutics Inc. Common Stock (ACRV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	HURA	ACRV	Difference
Sharpe ratio Return per unit of total volatility	-0.23	0.45	-0.68
Sortino ratio Return per unit of downside risk	0.64	1.32	-0.68
Omega ratio Gain probability vs. loss probability	1.08	1.17	-0.10
Calmar ratio Return relative to maximum drawdown	-0.33	0.87	-1.20
Martin ratio Return relative to average drawdown	-0.68	1.77	-2.44
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

HURA vs. ACRV - Sharpe Ratio Comparison

The current HURA Sharpe Ratio is -0.23, which is lower than the ACRV Sharpe Ratio of 0.45. The chart below compares the historical Sharpe Ratios of HURA and ACRV, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	HURA	ACRV	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.23	0.45	-0.68
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.54	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.52	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.45	-0.47	+0.02

Drawdowns

HURA vs. ACRV - Drawdown Comparison

The maximum HURA drawdown since its inception was -100.00%, roughly equal to the maximum ACRV drawdown of -95.47%. Use the drawdown chart below to compare losses from any high point for HURA and ACRV.

Drawdown Indicators

	HURA	ACRV	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-95.47%	-4.53%
Max Drawdown (1Y) Largest decline over 1 year	-86.46%	-57.14%	-29.32%
Max Drawdown (3Y) Largest decline over 3 years	-99.76%	-92.31%	-7.45%
Max Drawdown (5Y) Largest decline over 5 years	-99.99%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-100.00%	—	—
Current Drawdown Current decline from peak	-100.00%	-93.23%	-6.77%
Average Drawdown Average peak-to-trough decline	-88.32%	-70.39%	-17.93%
Ulcer Index Depth and duration of drawdowns from previous peaks	42.54%	28.03%	+14.51%

Volatility

HURA vs. ACRV - Volatility Comparison

TuHURA Biosciences, Inc. (HURA) has a higher volatility of 23.78% compared to Acrivon Therapeutics Inc. Common Stock (ACRV) at 17.27%. This indicates that HURA's price experiences larger fluctuations and is considered to be riskier than ACRV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	HURA	ACRV	Difference
Volatility (1M) Calculated over the trailing 1-month period	23.78%	17.27%	+6.51%
Volatility (6M) Calculated over the trailing 6-month period	112.80%	73.74%	+39.06%
Volatility (1Y) Calculated over the trailing 1-year period	134.30%	92.51%	+41.79%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	140.43%	103.93%	+36.50%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	128.41%	103.93%	+24.48%

Dividends

HURA vs. ACRV - Dividend Comparison

Neither HURA nor ACRV has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both HURA and ACRV in my portfolio?

HURA and ACRV have a correlation of 0.19, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, HURA or ACRV?

HURA has higher volatility (23.78%) compared to ACRV (17.27%). In terms of maximum drawdown, HURA dropped -100.00% vs ACRV's -95.47%.

Which has better risk-adjusted returns?

ACRV currently has the higher Sharpe Ratio (0.45 vs -0.23), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.