HHLE.TO vs. XDNA.TO
HHLE.TO (Harvest Healthcare Leaders Enhanced Income ETF - Class A Units) and XDNA.TO (iShares Genomics Immunology and Healthcare Index ETF) are both Health & Biotech Equities funds. HHLE.TO is actively managed, while XDNA.TO is passively managed. Over the past 3 years, HHLE.TO returned 3.15%/yr vs 7.28%/yr for XDNA.TO. At a 0.18 correlation, their price movements are largely independent. HHLE.TO charges 0.85%/yr vs 0.44%/yr for XDNA.TO.
Performance
HHLE.TO vs. XDNA.TO - Performance Comparison
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Returns By Period
In the year-to-date period, HHLE.TO achieves a -10.95% return, which is significantly lower than XDNA.TO's 10.45% return.
HHLE.TO
- 1D
- 0.90%
- 1M
- 0.01%
- YTD
- -10.95%
- 6M
- -10.74%
- 1Y
- 4.08%
- 3Y*
- 3.15%
- 5Y*
- —
- 10Y*
- —
XDNA.TO
- 1D
- -1.95%
- 1M
- -1.11%
- YTD
- 10.45%
- 6M
- 9.39%
- 1Y
- 40.18%
- 3Y*
- 7.28%
- 5Y*
- —
- 10Y*
- —
HHLE.TO vs. XDNA.TO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
HHLE.TO Harvest Healthcare Leaders Enhanced Income ETF - Class A Units | -10.95% | 11.85% | 3.28% | 7.14% | 5.96% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 10.45% | 12.10% | 5.54% | -7.84% | -5.28% |
Correlation
The correlation between HHLE.TO and XDNA.TO is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.24 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.19 |
Correlation (All Time) Calculated using the full available price history since Oct 26, 2022 | 0.18 |
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Return for Risk
HHLE.TO vs. XDNA.TO — Risk / Return Rank
HHLE.TO
XDNA.TO
HHLE.TO vs. XDNA.TO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Harvest Healthcare Leaders Enhanced Income ETF - Class A Units (HHLE.TO) and iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| HHLE.TO | XDNA.TO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.42 | ||
| Sortino ratioReturn per unit of downside risk | -1.99 | ||
| Omega ratioGain probability vs. loss probability | 1.05 | 1.30 | -0.24 |
| Calmar ratioReturn relative to maximum drawdown | 0.25 | 4.67 | -4.42 |
| Martin ratioReturn relative to average drawdown | 0.62 | 10.95 | -10.32 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| HHLE.TO | XDNA.TO | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.22 | 1.65 | -1.42 |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.27 | 0.04 | +0.22 |
Drawdowns
HHLE.TO vs. XDNA.TO - Drawdown Comparison
The maximum HHLE.TO drawdown since its inception was -20.60%, smaller than the maximum XDNA.TO drawdown of -45.90%. Use the drawdown chart below to compare losses from any high point for HHLE.TO and XDNA.TO.
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Drawdown Indicators
| HHLE.TO | XDNA.TO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -20.60% | -45.90% | +25.30% |
Max Drawdown (1Y)Largest decline over 1 year | -16.36% | -8.64% | -7.72% |
Max Drawdown (3Y)Largest decline over 3 years | -20.60% | -28.29% | +7.69% |
Current DrawdownCurrent decline from peak | -14.87% | -8.95% | -5.92% |
Average DrawdownAverage peak-to-trough decline | -6.56% | -23.55% | +16.99% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.57% | 3.68% | +2.89% |
Volatility
HHLE.TO vs. XDNA.TO - Volatility Comparison
Harvest Healthcare Leaders Enhanced Income ETF - Class A Units (HHLE.TO) has a higher volatility of 7.61% compared to iShares Genomics Immunology and Healthcare Index ETF (XDNA.TO) at 6.47%. This indicates that HHLE.TO's price experiences larger fluctuations and is considered to be riskier than XDNA.TO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| HHLE.TO | XDNA.TO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 7.61% | 6.47% | +1.14% |
Volatility (6M)Calculated over the trailing 6-month period | 13.23% | 18.03% | -4.80% |
Volatility (1Y)Calculated over the trailing 1-year period | 18.44% | 24.71% | -6.27% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 16.62% | 25.32% | -8.70% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 16.62% | 25.32% | -8.70% |
HHLE.TO vs. XDNA.TO - Expense Ratio Comparison
HHLE.TO has a 0.85% expense ratio, which is higher than XDNA.TO's 0.44% expense ratio.
Dividends
HHLE.TO vs. XDNA.TO - Dividend Comparison
HHLE.TO's dividend yield for the trailing twelve months is around 14.25%, more than XDNA.TO's 0.39% yield.
| Position | TTM | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
HHLE.TO Harvest Healthcare Leaders Enhanced Income ETF - Class A Units | 14.25% | 12.01% | 11.76% | 10.81% | 1.73% |
XDNA.TO iShares Genomics Immunology and Healthcare Index ETF | 0.39% | 0.43% | 0.32% | 0.25% | 0.32% |
Frequently Asked Questions
HHLE.TO and XDNA.TO have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, XDNA.TO is cheaper at 0.44% per year. The better choice depends on whether you care most about return, fees, risk, or income.
XDNA.TO is cheaper with a 0.44% expense ratio, compared with 0.85% for HHLE.TO.
They also come from different issuers: Harvest and iShares. Their fees differ too: 0.85% for HHLE.TO and 0.44% for XDNA.TO.
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