GRAL vs. AMD

Last updated Apr 1, 2026

Compare and contrast key facts about GRAIL, Inc (GRAL) and Advanced Micro Devices, Inc. (AMD).

Performance

GRAL vs. AMD - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in GRAIL, Inc (GRAL) and Advanced Micro Devices, Inc. (AMD). The values are adjusted to include any dividend payments, if applicable.

GRAL vs. AMD - Yearly Performance Comparison

	2026 (YTD)	2025	2024
GRAL GRAIL, Inc	-39.62%	379.50%	5.00%
AMD Advanced Micro Devices, Inc.	-5.01%	77.30%	-24.62%

Fundamentals

Market Cap GRAL : $2.10B AMD : $335.46B
EPS GRAL : -$10.95 AMD : $2.64
PS Ratio GRAL : 13.10 AMD : 9.63
PB Ratio GRAL : 0.82 AMD : 5.32
Total Revenue (TTM) GRAL : $147.17M AMD : $34.64B
Gross Profit (TTM) GRAL : -$62.57M AMD : $17.15B
EBITDA (TTM) GRAL : -$377.82M AMD : $6.18B

Returns By Period

In the year-to-date period, GRAL achieves a -39.62% return, which is significantly lower than AMD's -5.01% return.

GRAL

• 1D: 10.19%
• 1M: -2.91%
• YTD: -39.62%
• 6M: -12.60%
• 1Y: 102.35%
• 3Y*: —
• 5Y*: —
• 10Y*: —

AMD

• 1D: 3.77%
• 1M: 1.61%
• YTD: -5.01%
• 6M: 25.74%
• 1Y: 98.00%
• 3Y*: 27.56%
• 5Y*: 20.20%
• 10Y*: 53.34%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

GRAL vs. AMD — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GRAL

GRAL Risk / Return Rank: 73
GRAL Sharpe Ratio Rank: 73
GRAL Sortino Ratio Rank: 74
GRAL Omega Ratio Rank: 76
GRAL Calmar Ratio Rank: 70
GRAL Martin Ratio Rank: 71

AMD

AMD Risk / Return Rank: 85
AMD Sharpe Ratio Rank: 85
AMD Sortino Ratio Rank: 84
AMD Omega Ratio Rank: 83
AMD Calmar Ratio Rank: 89
AMD Martin Ratio Rank: 84

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GRAL vs. AMD - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for GRAIL, Inc (GRAL) and Advanced Micro Devices, Inc. (AMD). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	GRAL	AMD	Difference
Sharpe ratio Return per unit of total volatility	0.94	1.52	-0.58
Sortino ratio Return per unit of downside risk	1.80	2.31	-0.51
Omega ratio Gain probability vs. loss probability	1.26	1.30	-0.05
Calmar ratio Return relative to maximum drawdown	1.46	3.50	-2.04
Martin ratio Return relative to average drawdown	3.64	7.16	-3.52
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

GRAL vs. AMD - Sharpe Ratio Comparison

The current GRAL Sharpe Ratio is 0.94, which is lower than the AMD Sharpe Ratio of 1.52. The chart below compares the historical Sharpe Ratios of GRAL and AMD, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	GRAL	AMD	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.94	1.52	-0.58
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.38	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.91	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.81	0.13	+0.69

Correlation

The correlation between GRAL and AMD is 0.28, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

GRAL vs. AMD - Dividend Comparison

Neither GRAL nor AMD has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

GRAL vs. AMD - Drawdown Comparison

The maximum GRAL drawdown since its inception was -62.92%, smaller than the maximum AMD drawdown of -96.59%. Use the drawdown chart below to compare losses from any high point for GRAL and AMD.

Drawdown Indicators

	GRAL	AMD	Difference
Max Drawdown Largest peak-to-trough decline	-62.92%	-96.59%	+33.67%
Max Drawdown (1Y) Largest decline over 1 year	-62.92%	-27.76%	-35.16%
Max Drawdown (5Y) Largest decline over 5 years	—	-65.45%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-65.45%	—
Current Drawdown Current decline from peak	-55.47%	-23.04%	-32.43%
Average Drawdown Average peak-to-trough decline	-24.67%	-56.90%	+32.23%
Ulcer Index Depth and duration of drawdowns from previous peaks	25.25%	13.56%	+11.69%

Volatility

GRAL vs. AMD - Volatility Comparison

GRAIL, Inc (GRAL) has a higher volatility of 20.26% compared to Advanced Micro Devices, Inc. (AMD) at 16.50%. This indicates that GRAL's price experiences larger fluctuations and is considered to be riskier than AMD based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GRAL	AMD	Difference
Volatility (1M) Calculated over the trailing 1-month period	20.26%	16.50%	+3.76%
Volatility (6M) Calculated over the trailing 6-month period	96.74%	49.06%	+47.68%
Volatility (1Y) Calculated over the trailing 1-year period	109.57%	64.69%	+44.88%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	109.07%	53.46%	+55.61%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	109.07%	58.64%	+50.43%

Financials