GILD vs. SNY

Last updated Apr 3, 2026

Compare and contrast key facts about Gilead Sciences, Inc. (GILD) and Sanofi (SNY).

Performance

GILD vs. SNY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Gilead Sciences, Inc. (GILD) and Sanofi (SNY). The values are adjusted to include any dividend payments, if applicable.

GILD vs. SNY - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
GILD Gilead Sciences, Inc.	14.47%	36.59%	18.68%	-1.99%	23.63%	29.95%	-6.70%	7.88%	-9.92%	2.96%
SNY Sanofi	-1.18%	4.93%	1.09%	6.55%	0.57%	7.00%	0.39%	20.47%	6.06%	9.96%

Fundamentals

Market Cap GILD : $175.06B SNY : $116.89B
EPS GILD : $6.79 SNY : $3.18
PE Ratio GILD : 20.59 SNY : 15.07
PS Ratio GILD : 5.95 SNY : 2.52
PB Ratio GILD : 7.74 SNY : 1.64
Total Revenue (TTM) GILD : $29.44B SNY : $46.72B
Gross Profit (TTM) GILD : $23.79B SNY : $33.79B
EBITDA (TTM) GILD : $12.90B SNY : $12.68B

Returns By Period

In the year-to-date period, GILD achieves a 14.47% return, which is significantly higher than SNY's -1.18% return. Over the past 10 years, GILD has outperformed SNY with an annualized return of 7.76%, while SNY has yielded a comparatively lower 5.50% annualized return.

GILD

• 1D: -0.42%
• 1M: -4.96%
• YTD: 14.47%
• 6M: 27.92%
• 1Y: 28.18%
• 3Y*: 22.94%
• 5Y*: 20.43%
• 10Y*: 7.76%

SNY

• 1D: 0.34%
• 1M: 3.06%
• YTD: -1.18%
• 6M: -4.49%
• 1Y: -7.30%
• 3Y*: -0.05%
• 5Y*: 3.42%
• 10Y*: 5.50%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

GILD vs. SNY — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GILD

GILD Risk / Return Rank: 71
GILD Sharpe Ratio Rank: 72
GILD Sortino Ratio Rank: 68
GILD Omega Ratio Rank: 63
GILD Calmar Ratio Rank: 76
GILD Martin Ratio Rank: 77

SNY

SNY Risk / Return Rank: 25
SNY Sharpe Ratio Rank: 28
SNY Sortino Ratio Rank: 24
SNY Omega Ratio Rank: 24
SNY Calmar Ratio Rank: 25
SNY Martin Ratio Rank: 25

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

GILD vs. SNY - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Gilead Sciences, Inc. (GILD) and Sanofi (SNY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	GILD	SNY	Difference
Sharpe ratio Return per unit of total volatility	0.98	-0.27	+1.24
Sortino ratio Return per unit of downside risk	1.58	-0.18	+1.76
Omega ratio Gain probability vs. loss probability	1.18	0.98	+0.21
Calmar ratio Return relative to maximum drawdown	2.10	-0.45	+2.54
Martin ratio Return relative to average drawdown	5.65	-0.88	+6.52
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

GILD vs. SNY - Sharpe Ratio Comparison

The current GILD Sharpe Ratio is 0.98, which is higher than the SNY Sharpe Ratio of -0.27. The chart below compares the historical Sharpe Ratios of GILD and SNY, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	GILD	SNY	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.98	-0.27	+1.24
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.86	0.14	+0.72
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.30	0.24	+0.07
Sharpe Ratio (All Time) Calculated using the full available price history	0.39	0.21	+0.18

Correlation

The correlation between GILD and SNY is 0.33, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

GILD vs. SNY - Dividend Comparison

GILD's dividend yield for the trailing twelve months is around 2.28%, less than SNY's 4.62% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
GILD Gilead Sciences, Inc.	2.28%	2.57%	3.33%	3.70%	3.40%	3.91%	4.67%	3.88%	3.65%	2.90%	2.57%	1.27%
SNY Sanofi	4.62%	4.56%	4.22%	3.83%	4.32%	3.80%	3.61%	3.47%	4.29%	3.82%	4.11%	3.77%

Drawdowns

GILD vs. SNY - Drawdown Comparison

The maximum GILD drawdown since its inception was -70.83%, which is greater than SNY's maximum drawdown of -46.46%. Use the drawdown chart below to compare losses from any high point for GILD and SNY.

Drawdown Indicators

	GILD	SNY	Difference
Max Drawdown Largest peak-to-trough decline	-70.83%	-46.46%	-24.37%
Max Drawdown (1Y) Largest decline over 1 year	-13.77%	-17.87%	+4.10%
Max Drawdown (5Y) Largest decline over 5 years	-26.59%	-33.52%	+6.93%
Max Drawdown (10Y) Largest decline over 10 years	-36.01%	-33.52%	-2.49%
Current Drawdown Current decline from peak	-9.82%	-15.83%	+6.01%
Average Drawdown Average peak-to-trough decline	-22.20%	-12.15%	-10.05%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.12%	9.09%	-3.97%

Volatility

GILD vs. SNY - Volatility Comparison

The current volatility for Gilead Sciences, Inc. (GILD) is 6.34%, while Sanofi (SNY) has a volatility of 6.75%. This indicates that GILD experiences smaller price fluctuations and is considered to be less risky than SNY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GILD	SNY	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.34%	6.75%	-0.41%
Volatility (6M) Calculated over the trailing 6-month period	18.92%	15.99%	+2.93%
Volatility (1Y) Calculated over the trailing 1-year period	29.00%	27.43%	+1.57%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	23.89%	24.64%	-0.75%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.63%	23.51%	+2.12%

Financials

GILD vs. SNY - Profitability Comparison

The chart below illustrates the profitability comparison between Gilead Sciences, Inc. and Sanofi over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

GILD - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Gilead Sciences, Inc. reported a gross profit of 6.88B and revenue of 7.93B. Therefore, the gross margin over that period was 86.8%.

SNY - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Sanofi reported a gross profit of 8.58B and revenue of 12.21B. Therefore, the gross margin over that period was 70.3%.

GILD - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Gilead Sciences, Inc. reported an operating income of 2.96B and revenue of 7.93B, resulting in an operating margin of 37.4%.

SNY - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Sanofi reported an operating income of -1.04B and revenue of 12.21B, resulting in an operating margin of -8.5%.

GILD - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Gilead Sciences, Inc. reported a net income of 2.18B and revenue of 7.93B, resulting in a net margin of 27.6%.

SNY - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Sanofi reported a net income of -801.00M and revenue of 12.21B, resulting in a net margin of -6.6%.