GH vs. CELC

Last updated Aug 1, 2026

GH (Guardant Health, Inc.) and CELC (Celcuity Inc.) are both stocks. Both operate in the Diagnostics & Research industry within the Healthcare sector. Over the past 5 years, GH returned 8.09%/yr vs 34.40%/yr for CELC. Their 0.24 correlation means their historical movements had little consistent relationship.

Performance

GH vs. CELC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Guardant Health, Inc. (GH) and Celcuity Inc. (CELC). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, GH achieves a 58.60% return, which is significantly higher than CELC's -13.39% return.

GH

• 1D: 6.33%
• 1M: -3.57%
• 6M: 42.05%
• YTD: 58.60%
• 1Y: 291.09%
• 3Y*: 62.15%
• 5Y*: 8.09%
• 10Y*: —
• ALL TIME*: 25.30%

CELC

• 1D: -1.44%
• 1M: -19.98%
• 6M: -21.06%
• YTD: -13.39%
• 1Y: 116.44%
• 3Y*: 105.46%
• 5Y*: 34.40%
• 10Y*: —
• ALL TIME*: 24.55%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
CELC Celcuity Inc.	$119.16M	$168.28M	$170.21M
GH Guardant Health, Inc.	$318.22M	$357.11M	$367.60M

GH vs. CELC - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
GH Guardant Health, Inc.	58.60%	234.34%	12.94%	-0.55%	-72.81%	-22.39%	64.93%	107.87%	35.46%
CELC Celcuity Inc.	-13.39%	661.96%	-10.16%	4.00%	6.22%	44.00%	-13.91%	-55.65%	-16.76%

Correlation

The correlation between GH and CELC is 0.31, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.31
Correlation (3Y) Balances recent behavior with more history.	0.27
Correlation (5Y) Shows whether the relationship held over a longer period.	0.28
Correlation (All Time) Calculated using the full available price history since Oct 4, 2018	0.24

Fundamentals

Market Cap GH : $21.48B CELC : $4.21B
EPS GH : -$3.51 CELC : -$3.81
Total Revenue (TTM) GH : $1.18B CELC : $0.00
Gross Profit (TTM) GH : $769.16M CELC : -$41.00K
EBITDA (TTM) GH : -$431.26M CELC : -$168.13M

Return for Risk

GH vs. CELC — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

GH

GH Risk / Return Rank: 98
GH Sharpe Ratio Rank: 99
GH Sortino Ratio Rank: 99
GH Omega Ratio Rank: 98
GH Calmar Ratio Rank: 98
GH Martin Ratio Rank: 98

CELC

CELC Risk / Return Rank: 85
CELC Sharpe Ratio Rank: 86
CELC Sortino Ratio Rank: 84
CELC Omega Ratio Rank: 86
CELC Calmar Ratio Rank: 86
CELC Martin Ratio Rank: 86

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

GH vs. CELC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Guardant Health, Inc. (GH) and Celcuity Inc. (CELC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	GH	CELC	Difference
Sharpe ratio: Return per unit of total volatility	4.93	1.58	+3.35
Sortino ratio: Return per unit of downside risk	5.02	2.26	+2.76
Omega ratio: Gain probability vs. loss probability	1.63	1.31	+0.32
Calmar ratio: Return relative to maximum drawdown	9.02	2.80	+6.22
Martin ratio: Return relative to average drawdown	22.69	7.33	+15.36

GH vs. CELC - Sharpe Ratio Comparison

The current GH Sharpe Ratio is 4.93, which is higher than the CELC Sharpe Ratio of 1.58. The chart below compares the historical Sharpe Ratios of GH and CELC, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

GH vs. CELC - Drawdown Comparison

The maximum GH drawdown since its inception was -91.03%, which is greater than CELC's maximum drawdown of -85.64%. Use the drawdown chart below to compare losses from any high point for GH and CELC.

Drawdown Indicators

	GH	CELC	Difference
Max Drawdown Largest peak-to-trough decline	-91.03%	-85.64%	-5.39%
Max Drawdown (1Y) Largest decline over 1 year	-32.98%	-43.25%	+10.27%
Max Drawdown (3Y) Largest decline over 3 years	-59.79%	-61.99%	+2.20%
Max Drawdown (5Y) Largest decline over 5 years	-87.84%	-76.32%	-11.52%
Current Drawdown Current decline from peak	-9.55%	-40.42%	+30.87%
Average Drawdown Average peak-to-trough decline	-50.97%	-44.81%	-6.16%
Ulcer Index Depth and duration of drawdowns from previous peaks	13.08%	16.51%	-3.43%

Volatility

GH vs. CELC - Volatility Comparison

The current volatility for Guardant Health, Inc. (GH) is 14.67%, while Celcuity Inc. (CELC) has a volatility of 26.36%. This indicates that GH experiences smaller price fluctuations and is considered to be less risky than CELC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	GH	CELC	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.67%	26.36%	-11.69%
Volatility (6M) Calculated over the trailing 6-month period	41.58%	54.17%	-12.59%
Volatility (1Y) Calculated over the trailing 1-year period	61.10%	76.79%	-15.69%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	68.10%	101.04%	-32.94%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	68.19%	91.43%	-23.24%

Dividends

GH vs. CELC - Dividend Comparison

Neither GH nor CELC has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both GH and CELC in my portfolio?

GH and CELC have a correlation of 0.31, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, GH or CELC?

CELC has higher volatility (26.36%) compared to GH (14.67%). In terms of maximum drawdown, GH dropped -91.03% vs CELC's -85.64%.

Which has better risk-adjusted returns?

GH currently has the higher Sharpe Ratio (4.93 vs 1.58), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.