GH vs. TMDX
GH (Guardant Health, Inc.) and TMDX (TransMedics Group, Inc.) are both stocks. Both are in the Healthcare sector — GH in Diagnostics & Research, TMDX in Medical Devices. Over the past 5 years, GH returned 8.09%/yr vs 21.82%/yr for TMDX. Their 0.32 correlation means their historical movements had little consistent relationship.
Performance
GH vs. TMDX - Performance Comparison
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Returns By Period
In the year-to-date period, GH achieves a 58.60% return, which is significantly higher than TMDX's -37.11% return.
GH
- 1D
- 6.33%
- 1M
- -3.57%
- 6M
- 42.05%
- YTD
- 58.60%
- 1Y
- 291.09%
- 3Y*
- 62.15%
- 5Y*
- 8.09%
- 10Y*
- —
- ALL TIME*
- 25.30%
TMDX
- 1D
- 0.50%
- 1M
- 11.11%
- 6M
- -42.89%
- YTD
- -37.11%
- 1Y
- -36.53%
- 3Y*
- -6.59%
- 5Y*
- 21.82%
- 10Y*
- —
- ALL TIME*
- 20.13%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $318.22M | $357.11M | $367.60M | |
| $63.45M | $59.50M | $94.77M |
GH vs. TMDX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | |
|---|---|---|---|---|---|---|---|---|
GH Guardant Health, Inc. | 58.60% | 234.34% | 12.94% | -0.55% | -72.81% | -22.39% | 64.93% | 20.20% |
TMDX TransMedics Group, Inc. | -37.11% | 95.11% | -21.01% | 27.88% | 222.13% | -3.72% | 4.68% | -6.12% |
Correlation
The correlation between GH and TMDX is 0.15, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.15 |
Correlation (3Y) Balances recent behavior with more history. | 0.27 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.36 |
Correlation (All Time) Calculated using the full available price history since May 2, 2019 | 0.32 |
The correlation between GH and TMDX shifts across timeframes, from 0.15 (1 year) to 0.36 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
GH:
$21.48B
TMDX:
$2.64B
GH:
-$3.51
TMDX:
$4.38
GH:
17.71
TMDX:
4.73
GH:
$1.18B
TMDX:
$635.89M
GH:
$769.16M
TMDX:
$375.74M
GH:
-$431.26M
TMDX:
$125.51M
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Return for Risk
GH vs. TMDX — Risk / Return Rank
GH
TMDX
GH vs. TMDX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Guardant Health, Inc. (GH) and TransMedics Group, Inc. (TMDX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| GH | TMDX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +5.56 | ||
| Sortino ratioReturn per unit of downside risk | +5.66 | ||
| Omega ratioGain probability vs. loss probability | 1.63 | 0.92 | +0.71 |
| Calmar ratioReturn relative to maximum drawdown | 9.02 | -0.61 | +9.63 |
| Martin ratioReturn relative to average drawdown | 22.69 | -1.22 | +23.91 |
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Drawdowns
GH vs. TMDX - Drawdown Comparison
The maximum GH drawdown since its inception was -91.03%, which is greater than TMDX's maximum drawdown of -73.69%. Use the drawdown chart below to compare losses from any high point for GH and TMDX.
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Drawdown Indicators
| GH | TMDX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -91.03% | -73.69% | -17.34% |
Max Drawdown (1Y)Largest decline over 1 year | -32.98% | -58.76% | +25.78% |
Max Drawdown (3Y)Largest decline over 3 years | -59.79% | -67.79% | +8.00% |
Max Drawdown (5Y)Largest decline over 5 years | -87.84% | -67.79% | -20.05% |
Current DrawdownCurrent decline from peak | -9.55% | -56.56% | +47.01% |
Average DrawdownAverage peak-to-trough decline | -50.97% | -32.37% | -18.60% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 13.08% | 29.29% | -16.21% |
Volatility
GH vs. TMDX - Volatility Comparison
Guardant Health, Inc. (GH) has a higher volatility of 14.67% compared to TransMedics Group, Inc. (TMDX) at 10.87%. This indicates that GH's price experiences larger fluctuations and is considered to be riskier than TMDX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| GH | TMDX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 14.67% | 10.87% | +3.80% |
Volatility (6M)Calculated over the trailing 6-month period | 41.58% | 46.16% | -4.58% |
Volatility (1Y)Calculated over the trailing 1-year period | 61.10% | 58.45% | +2.65% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 68.10% | 71.84% | -3.74% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 68.19% | 71.46% | -3.27% |
Dividends
GH vs. TMDX - Dividend Comparison
Neither GH nor TMDX has paid dividends to shareholders.
Financials
GH vs. TMDX - Financials Comparison
This section allows you to compare key financial metrics between Guardant Health, Inc. and TransMedics Group, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
GH vs. TMDX - Profitability Comparison
GH - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Guardant Health, Inc. reported a gross profit of 219.03M and revenue of 334.98M. Therefore, the gross margin over that period was 65.4%.
TMDX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, TransMedics Group, Inc. reported a gross profit of 101.16M and revenue of 173.93M. Therefore, the gross margin over that period was 58.2%.
GH - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Guardant Health, Inc. reported an operating income of -129.12M and revenue of 334.98M, resulting in an operating margin of -38.6%.
TMDX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, TransMedics Group, Inc. reported an operating income of 13.30M and revenue of 173.93M, resulting in an operating margin of 7.6%.
GH - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Guardant Health, Inc. reported a net income of -120.14M and revenue of 334.98M, resulting in a net margin of -35.9%.
TMDX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, TransMedics Group, Inc. reported a net income of 7.32M and revenue of 173.93M, resulting in a net margin of 4.2%.
Frequently Asked Questions
GH and TMDX have a correlation of 0.15, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
GH has higher volatility (14.67%) compared to TMDX (10.87%). In terms of maximum drawdown, GH dropped -91.03% vs TMDX's -73.69%.
GH currently has the higher Sharpe Ratio (4.93 vs -0.62), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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