FTXH vs. GERM

Last updated Jun 5, 2026

FTXH (First Trust Nasdaq Pharmaceuticals ETF) and GERM (Amplify Treatments, Testing and Advancements ETF) are both Health & Biotech Equities funds - FTXH tracks the Nasdaq U.S. Smart Pharmaceuticals Index while GERM tracks the Prime Treatments, Testing and Advancements Index. Both are passively managed. Over the past year, FTXH returned 39.54% vs 0.00% for GERM. FTXH charges 0.60%/yr vs 0.68%/yr for GERM.

Performance

FTXH vs. GERM - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in First Trust Nasdaq Pharmaceuticals ETF (FTXH) and Amplify Treatments, Testing and Advancements ETF (GERM). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

FTXH

• 1D: 2.50%
• 1M: 3.66%
• YTD: 7.62%
• 6M: 9.20%
• 1Y: 39.54%
• 3Y*: 12.33%
• 5Y*: 8.33%
• 10Y*: —

GERM

• 1D: 0.00%
• 1M: 0.00%
• YTD: 0.00%
• 6M: 0.00%
• 1Y: 0.00%
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

FTXH vs. GERM - Yearly Performance Comparison

	2026 (YTD)	2025	2024
FTXH First Trust Nasdaq Pharmaceuticals ETF	7.62%	24.15%	-5.22%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%

FTXH vs. GERM - Sectors Allocation Comparison

Sectors	FTXH	GERM
Healthcare	100.0%	99.3%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.4%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

FTXH vs. GERM — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

FTXH

FTXH Risk / Return Rank: 77
FTXH Sharpe Ratio Rank: 72
FTXH Sortino Ratio Rank: 77
FTXH Omega Ratio Rank: 67
FTXH Calmar Ratio Rank: 89
FTXH Martin Ratio Rank: 80

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

FTXH vs. GERM - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for First Trust Nasdaq Pharmaceuticals ETF (FTXH) and Amplify Treatments, Testing and Advancements ETF (GERM). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	FTXH	GERM	Difference
Sharpe ratio: Return per unit of total volatility	2.32	—	—
Sortino ratio: Return per unit of downside risk	3.40	—	—
Omega ratio: Gain probability vs. loss probability	1.39	—	—
Calmar ratio: Return relative to maximum drawdown	5.32	—	—
Martin ratio: Return relative to average drawdown	15.35	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	FTXH	GERM	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.32	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.51	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.39	—	—

Drawdowns

FTXH vs. GERM - Drawdown Comparison

The maximum FTXH drawdown since its inception was -32.11%, which is greater than GERM's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for FTXH and GERM.

Drawdown Indicators

	FTXH	GERM	Difference
Max Drawdown Largest peak-to-trough decline	-32.11%	0.00%	-32.11%
Max Drawdown (1Y) Largest decline over 1 year	-7.47%	0.00%	-7.47%
Max Drawdown (3Y) Largest decline over 3 years	-19.51%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-19.51%	—	—
Current Drawdown Current decline from peak	-0.45%	0.00%	-0.45%
Average Drawdown Average peak-to-trough decline	-5.84%	0.00%	-5.84%
Ulcer Index Depth and duration of drawdowns from previous peaks	2.58%	0.00%	+2.58%

Volatility

FTXH vs. GERM - Volatility Comparison

First Trust Nasdaq Pharmaceuticals ETF (FTXH) has a higher volatility of 5.38% compared to Amplify Treatments, Testing and Advancements ETF (GERM) at 0.00%. This indicates that FTXH's price experiences larger fluctuations and is considered to be riskier than GERM based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	FTXH	GERM	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.38%	0.00%	+5.38%
Volatility (6M) Calculated over the trailing 6-month period	11.96%	0.00%	+11.96%
Volatility (1Y) Calculated over the trailing 1-year period	17.14%	0.00%	+17.14%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	16.34%	0.00%	+16.34%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.43%	0.00%	+18.43%

FTXH vs. GERM - Expense Ratio Comparison

FTXH has a 0.60% expense ratio, which is lower than GERM's 0.68% expense ratio.

Dividends

FTXH vs. GERM - Dividend Comparison

FTXH's dividend yield for the trailing twelve months is around 1.19%, while GERM has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
FTXH First Trust Nasdaq Pharmaceuticals ETF	1.19%	1.41%	1.66%	1.55%	1.11%	1.03%	0.82%	0.67%	0.91%	2.18%	0.19%
GERM Amplify Treatments, Testing and Advancements ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Which is riskier, FTXH or GERM?

FTXH has higher volatility (5.38%) compared to GERM (0.00%). In terms of maximum drawdown, FTXH dropped -32.11% vs GERM's 0.00%.

Which ETF is better, FTXH or GERM?

On 1-year performance, FTXH leads with 39.54% vs 0.00% for GERM. On fees, FTXH is cheaper at 0.60% per year. On volatility, GERM has been the lower-risk option at 0.00%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, FTXH or GERM?

Over the 1-year period, FTXH has performed better with a 39.54% return vs 0.00%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, FTXH or GERM?

FTXH is cheaper with a 0.60% expense ratio, compared with 0.68% for GERM.

Which ETF pays a higher dividend yield, FTXH or GERM?

FTXH has the higher dividend yield at 1.19%, compared with 0.00% for GERM.

What is the main difference between FTXH and GERM?

FTXH tracks Nasdaq U.S. Smart Pharmaceuticals Index, while GERM tracks Prime Treatments, Testing and Advancements Index. They also come from different issuers: First Trust and Amplify. Their fees differ too: 0.60% for FTXH and 0.68% for GERM.