FBT vs. PBE

Last updated Jun 23, 2026

FBT (First Trust Amex Biotechnology Index) and PBE (Invesco Dynamic Biotechnology & Genome ETF) are both Health & Biotech Equities funds - FBT tracks the NYSE Arca Biotechnology Index while PBE tracks the Dynamic Biotech & Genome Intellidex Index (AMEX). Both are passively managed. Over the past 10 years, FBT returned 10.45%/yr vs 9.35%/yr for PBE. Their correlation of 0.89 suggests significant overlap in exposure. FBT charges 0.57%/yr vs 0.59%/yr for PBE.

Performance

FBT vs. PBE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in First Trust Amex Biotechnology Index (FBT) and Invesco Dynamic Biotechnology & Genome ETF (PBE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, FBT achieves a 11.27% return, which is significantly higher than PBE's 4.26% return. Over the past 10 years, FBT has outperformed PBE with an annualized return of 10.45%, while PBE has yielded a comparatively lower 9.35% annualized return.

FBT

• 1D: 0.41%
• 1M: 7.91%
• YTD: 11.27%
• 6M: 6.83%
• 1Y: 44.08%
• 3Y*: 13.78%
• 5Y*: 6.30%
• 10Y*: 10.45%

PBE

• 1D: 1.08%
• 1M: 4.15%
• YTD: 4.26%
• 6M: 2.94%
• 1Y: 35.92%
• 3Y*: 12.04%
• 5Y*: 2.24%
• 10Y*: 9.35%

*Multi-year figures are annualized to reflect compound growth (CAGR)

FBT vs. PBE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
FBT First Trust Amex Biotechnology Index	11.27%	24.25%	5.88%	2.55%	-4.83%	-2.26%	12.96%	19.74%	-0.30%	37.07%
PBE Invesco Dynamic Biotechnology & Genome ETF	4.26%	24.84%	1.10%	3.71%	-10.83%	1.54%	25.66%	18.65%	-0.19%	22.28%

Correlation

The correlation between FBT and PBE is 0.91, indicating a strong positive relationship between their price movements. Combining them offers limited diversification - they tend to fall together during downturns.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.91
Correlation (3Y) Calculated over the trailing 3-year period	0.89
Correlation (5Y) Calculated over the trailing 5-year period	0.90
Correlation (10Y) Calculated over the trailing 10-year period	0.90
Correlation (All Time) Calculated using the full available price history since Jun 23, 2006	0.89

The correlation between FBT and PBE has been stable across timeframes, ranging from 0.89 to 0.91 - a consistent structural relationship.

FBT vs. PBE - Sectors Allocation Comparison

Sectors	FBT	PBE
Healthcare	100.0%	99.9%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.1%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

FBT vs. PBE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

FBT

FBT Risk / Return Rank: 63
FBT Sharpe Ratio Rank: 67
FBT Sortino Ratio Rank: 69
FBT Omega Ratio Rank: 62
FBT Calmar Ratio Rank: 64
FBT Martin Ratio Rank: 54

PBE

PBE Risk / Return Rank: 58
PBE Sharpe Ratio Rank: 58
PBE Sortino Ratio Rank: 62
PBE Omega Ratio Rank: 53
PBE Calmar Ratio Rank: 64
PBE Martin Ratio Rank: 52

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

FBT vs. PBE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for First Trust Amex Biotechnology Index (FBT) and Invesco Dynamic Biotechnology & Genome ETF (PBE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	FBT	PBE	Difference
Sharpe ratio: Return per unit of total volatility	2.11	1.90	+0.20
Sortino ratio: Return per unit of downside risk	3.02	2.81	+0.21
Omega ratio: Gain probability vs. loss probability	1.36	1.32	+0.04
Calmar ratio: Return relative to maximum drawdown	3.11	3.08	+0.03
Martin ratio: Return relative to average drawdown	9.19	8.64	+0.55

FBT vs. PBE - Sharpe Ratio Comparison

The current FBT Sharpe Ratio is 2.11, which is comparable to the PBE Sharpe Ratio of 1.90. The chart below compares the historical Sharpe Ratios of FBT and PBE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

FBT vs. PBE - Drawdown Comparison

The maximum FBT drawdown since its inception was -40.51%, smaller than the maximum PBE drawdown of -45.69%. Use the drawdown chart below to compare losses from any high point for FBT and PBE.

Drawdown Indicators

	FBT	PBE	Difference
Max Drawdown Largest peak-to-trough decline	-40.51%	-45.69%	+5.18%
Max Drawdown (1Y) Largest decline over 1 year	-14.26%	-11.73%	-2.53%
Max Drawdown (3Y) Largest decline over 3 years	-20.05%	-22.43%	+2.38%
Max Drawdown (5Y) Largest decline over 5 years	-28.98%	-34.71%	+5.73%
Max Drawdown (10Y) Largest decline over 10 years	-32.37%	-37.84%	+5.47%
Current Drawdown Current decline from peak	0.00%	-0.10%	+0.10%
Average Drawdown Average peak-to-trough decline	-11.14%	-16.20%	+5.06%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.81%	4.17%	+0.64%

Volatility

FBT vs. PBE - Volatility Comparison

First Trust Amex Biotechnology Index (FBT) has a higher volatility of 6.54% compared to Invesco Dynamic Biotechnology & Genome ETF (PBE) at 5.59%. This indicates that FBT's price experiences larger fluctuations and is considered to be riskier than PBE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	FBT	PBE	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.54%	5.59%	+0.95%
Volatility (6M) Calculated over the trailing 6-month period	16.15%	13.68%	+2.47%
Volatility (1Y) Calculated over the trailing 1-year period	21.06%	19.00%	+2.06%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	21.88%	22.49%	-0.61%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	23.88%	24.88%	-1.00%

FBT vs. PBE - Expense Ratio Comparison

FBT has a 0.57% expense ratio, which is lower than PBE's 0.59% expense ratio.

Dividends

FBT vs. PBE - Dividend Comparison

FBT has not paid dividends to shareholders, while PBE's dividend yield for the trailing twelve months is around 1.98%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
FBT First Trust Amex Biotechnology Index	0.00%	0.00%	0.71%	0.00%	0.00%	1.37%	0.00%	0.00%	0.00%	0.00%	0.00%	0.12%
PBE Invesco Dynamic Biotechnology & Genome ETF	1.98%	1.00%	0.05%	0.02%	0.00%	0.00%	0.04%	0.00%	0.00%	0.57%	0.38%	1.12%

Frequently Asked Questions

Can I hold both FBT and PBE in my portfolio?

With a correlation of 0.91, FBT and PBE move almost identically. Holding both adds very little diversification - you're essentially doubling your position in the same market segment. Choosing one is usually more capital-efficient.

Which is riskier, FBT or PBE?

FBT has higher volatility (6.54%) compared to PBE (5.59%). In terms of maximum drawdown, FBT dropped -40.51% vs PBE's -45.69%.

Which ETF is better, FBT or PBE?

On 10-year performance, FBT leads with 10.45% vs 9.35% for PBE. On fees, FBT is cheaper at 0.57% per year. On volatility, PBE has been the lower-risk option at 5.59%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, FBT or PBE?

Over the 10-year period, FBT has performed better with a 10.45% return vs 9.35%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, FBT or PBE?

FBT is cheaper with a 0.57% expense ratio, compared with 0.59% for PBE.

Which ETF pays a higher dividend yield, FBT or PBE?

PBE has the higher dividend yield at 1.98%, compared with 0.00% for FBT.

What is the main difference between FBT and PBE?

FBT tracks NYSE Arca Biotechnology Index, while PBE tracks Dynamic Biotech & Genome Intellidex Index (AMEX). They also come from different issuers: First Trust and Invesco. Their fees differ too: 0.57% for FBT and 0.59% for PBE.

Which has better risk-adjusted returns?

FBT currently has the higher Sharpe Ratio (2.11 vs 1.90), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.