EXEL vs. ALPMY
EXEL (Exelixis, Inc.) and ALPMY (Astellas Pharma Inc) are both stocks. Both are in the Healthcare sector — EXEL in Biotechnology, ALPMY in Drug Manufacturers - General. Over the past 10 years, EXEL returned 21.26%/yr vs -0.40%/yr for ALPMY. At a 0.14 correlation, their price movements are largely independent.
Performance
EXEL vs. ALPMY - Performance Comparison
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Returns By Period
In the year-to-date period, EXEL achieves a 20.63% return, which is significantly higher than ALPMY's 0.45% return. Over the past 10 years, EXEL has outperformed ALPMY with an annualized return of 21.26%, while ALPMY has yielded a comparatively lower -0.40% annualized return.
EXEL
- 1D
- 2.98%
- 1M
- 5.42%
- YTD
- 20.63%
- 6M
- 13.67%
- 1Y
- 15.64%
- 3Y*
- 38.59%
- 5Y*
- 17.69%
- 10Y*
- 21.26%
ALPMY
- 1D
- 1.44%
- 1M
- -6.05%
- YTD
- 0.45%
- 6M
- -0.37%
- 1Y
- 39.54%
- 3Y*
- -2.76%
- 5Y*
- -5.14%
- 10Y*
- -0.40%
EXEL vs. ALPMY - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
EXEL Exelixis, Inc. | 20.63% | 31.62% | 38.81% | 49.56% | -12.25% | -8.92% | 13.90% | -10.42% | -35.30% | 103.89% |
ALPMY Astellas Pharma Inc | 0.45% | 41.23% | -17.10% | -21.50% | -6.82% | 5.38% | -9.34% | 35.81% | -1.10% | -7.48% |
Correlation
The correlation between EXEL and ALPMY is 0.11, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.11 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.10 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.12 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.13 |
Correlation (All Time) Calculated using the full available price history since Dec 18, 2008 | 0.14 |
Fundamentals
EXEL:
$14.13B
ALPMY:
$23.99B
EXEL:
$3.00
ALPMY:
¥172.03
EXEL:
17.64
ALPMY:
12.55
EXEL:
0.31
ALPMY:
0.08
EXEL:
6.19
ALPMY:
1.71
EXEL:
7.30
ALPMY:
2.11
EXEL:
$2.38B
ALPMY:
¥2.27T
EXEL:
$1.70B
ALPMY:
¥1.69T
EXEL:
$991.79M
ALPMY:
¥445.01B
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Return for Risk
EXEL vs. ALPMY — Risk / Return Rank
EXEL
ALPMY
EXEL vs. ALPMY - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Exelixis, Inc. (EXEL) and Astellas Pharma Inc (ALPMY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| EXEL | ALPMY | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.99 | ||
| Sortino ratioReturn per unit of downside risk | -1.24 | ||
| Omega ratioGain probability vs. loss probability | 1.11 | 1.25 | -0.13 |
| Calmar ratioReturn relative to maximum drawdown | 0.62 | 1.84 | -1.22 |
| Martin ratioReturn relative to average drawdown | 1.51 | 4.90 | -3.39 |
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Drawdowns
EXEL vs. ALPMY - Drawdown Comparison
The maximum EXEL drawdown since its inception was -97.38%, which is greater than ALPMY's maximum drawdown of -83.67%. Use the drawdown chart below to compare losses from any high point for EXEL and ALPMY.
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Drawdown Indicators
| EXEL | ALPMY | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.38% | -83.67% | -13.71% |
Max Drawdown (1Y)Largest decline over 1 year | -25.16% | -21.57% | -3.59% |
Max Drawdown (3Y)Largest decline over 3 years | -25.34% | -40.38% | +15.04% |
Max Drawdown (5Y)Largest decline over 5 years | -36.12% | -49.11% | +12.99% |
Max Drawdown (10Y)Largest decline over 10 years | -57.20% | -49.67% | -7.53% |
Current DrawdownCurrent decline from peak | -1.18% | -75.34% | +74.16% |
Average DrawdownAverage peak-to-trough decline | -70.95% | -58.45% | -12.50% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 10.42% | 8.10% | +2.32% |
Volatility
EXEL vs. ALPMY - Volatility Comparison
Exelixis, Inc. (EXEL) and Astellas Pharma Inc (ALPMY) have volatilities of 9.76% and 10.11%, respectively, indicating that both stocks experience similar levels of price fluctuations. This suggests that the risk associated with both stocks, as measured by volatility, is nearly the same. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| EXEL | ALPMY | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 9.76% | 10.11% | -0.35% |
Volatility (6M)Calculated over the trailing 6-month period | 25.39% | 22.57% | +2.82% |
Volatility (1Y)Calculated over the trailing 1-year period | 39.72% | 28.81% | +10.91% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 37.17% | 25.45% | +11.72% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 44.48% | 25.58% | +18.90% |
Dividends
EXEL vs. ALPMY - Dividend Comparison
Neither EXEL nor ALPMY has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
ALPMY Astellas Pharma Inc | 0.00% | 1.93% | 2.56% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 1.20% | 2.18% |
EXEL Exelixis, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
EXEL vs. ALPMY - Financials Comparison
This section allows you to compare key financial metrics between Exelixis, Inc. and Astellas Pharma Inc. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
EXEL vs. ALPMY - Profitability Comparison
EXEL - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Exelixis, Inc. reported a gross profit of 0.00 and revenue of 610.81M. Therefore, the gross margin over that period was 0.0%.
ALPMY - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Astellas Pharma Inc reported a gross profit of 457.56B and revenue of 647.49B. Therefore, the gross margin over that period was 70.7%.
EXEL - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Exelixis, Inc. reported an operating income of 251.34M and revenue of 610.81M, resulting in an operating margin of 41.2%.
ALPMY - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Astellas Pharma Inc reported an operating income of 113.89B and revenue of 647.49B, resulting in an operating margin of 17.6%.
EXEL - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Exelixis, Inc. reported a net income of 210.47M and revenue of 610.81M, resulting in a net margin of 34.5%.
ALPMY - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Astellas Pharma Inc reported a net income of 57.97B and revenue of 647.49B, resulting in a net margin of 9.0%.
Frequently Asked Questions
EXEL and ALPMY have a correlation of 0.11, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ALPMY has higher volatility (10.11%) compared to EXEL (9.76%). In terms of maximum drawdown, EXEL dropped -97.38% vs ALPMY's -83.67%.
ALPMY currently has the higher Sharpe Ratio (1.39 vs 0.40), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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