ALPMY vs. DCTH

Last updated Jun 23, 2026

ALPMY (Astellas Pharma Inc) and DCTH (Delcath Systems, Inc.) are both stocks. Both are in the Healthcare sector — ALPMY in Drug Manufacturers - General, DCTH in Medical Devices. Over the past 5 years, ALPMY returned -4.56%/yr vs 1.93%/yr for DCTH. At a 0.11 correlation, their price movements are largely independent.

Performance

ALPMY vs. DCTH - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Astellas Pharma Inc (ALPMY) and Delcath Systems, Inc. (DCTH). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ALPMY achieves a 1.35% return, which is significantly lower than DCTH's 13.96% return.

ALPMY

• 1D: 0.15%
• 1M: -5.21%
• YTD: 1.35%
• 6M: 1.89%
• 1Y: 45.94%
• 3Y*: -2.47%
• 5Y*: -4.56%
• 10Y*: -0.31%

DCTH

• 1D: -1.54%
• 1M: 4.45%
• YTD: 13.96%
• 6M: 14.30%
• 1Y: -16.90%
• 3Y*: 27.37%
• 5Y*: 1.93%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

ALPMY vs. DCTH - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018
ALPMY Astellas Pharma Inc	1.35%	41.23%	-17.10%	-21.50%	-6.82%	5.38%	-9.34%	35.81%	-17.50%
DCTH Delcath Systems, Inc.	13.96%	-16.11%	189.42%	15.56%	-53.55%	-56.75%	-15.67%	-89.16%	-90.69%

Correlation

The correlation between ALPMY and DCTH is 0.12, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.12
Correlation (3Y) Calculated over the trailing 3-year period	0.09
Correlation (5Y) Calculated over the trailing 5-year period	0.10
Correlation (All Time) Calculated using the full available price history since May 29, 2018	0.11

Fundamentals

Market Cap ALPMY : $24.21B DCTH : $414.60M
EPS ALPMY : ¥172.03 DCTH : $0.01
PE Ratio ALPMY : 12.65 DCTH : 783.68
PS Ratio ALPMY : 1.72 DCTH : 6.72
PB Ratio ALPMY : 2.13 DCTH : 3.68
Total Revenue (TTM) ALPMY : ¥2.27T DCTH : $65.45M
Gross Profit (TTM) ALPMY : ¥1.69T DCTH : $77.75M
EBITDA (TTM) ALPMY : ¥445.01B DCTH : $222.00K

Return for Risk

ALPMY vs. DCTH — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ALPMY

ALPMY Risk / Return Rank: 80
ALPMY Sharpe Ratio Rank: 84
ALPMY Sortino Ratio Rank: 81
ALPMY Omega Ratio Rank: 78
ALPMY Calmar Ratio Rank: 77
ALPMY Martin Ratio Rank: 79

DCTH

DCTH Risk / Return Rank: 28
DCTH Sharpe Ratio Rank: 27
DCTH Sortino Ratio Rank: 27
DCTH Omega Ratio Rank: 27
DCTH Calmar Ratio Rank: 28
DCTH Martin Ratio Rank: 30

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ALPMY vs. DCTH - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Astellas Pharma Inc (ALPMY) and Delcath Systems, Inc. (DCTH). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ALPMY	DCTH	Difference
Sharpe ratio: Return per unit of total volatility	1.61	-0.34	+1.95
Sortino ratio: Return per unit of downside risk	2.28	-0.18	+2.46
Omega ratio: Gain probability vs. loss probability	1.28	0.98	+0.30
Calmar ratio: Return relative to maximum drawdown	2.17	-0.41	+2.58
Martin ratio: Return relative to average drawdown	5.85	-0.64	+6.49

ALPMY vs. DCTH - Sharpe Ratio Comparison

The current ALPMY Sharpe Ratio is 1.61, which is higher than the DCTH Sharpe Ratio of -0.34. The chart below compares the historical Sharpe Ratios of ALPMY and DCTH, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ALPMY vs. DCTH - Drawdown Comparison

The maximum ALPMY drawdown since its inception was -83.67%, smaller than the maximum DCTH drawdown of -99.96%. Use the drawdown chart below to compare losses from any high point for ALPMY and DCTH.

Drawdown Indicators

	ALPMY	DCTH	Difference
Max Drawdown Largest peak-to-trough decline	-83.67%	-99.96%	+16.29%
Max Drawdown (1Y) Largest decline over 1 year	-21.28%	-41.71%	+20.43%
Max Drawdown (3Y) Largest decline over 3 years	-40.38%	-62.87%	+22.49%
Max Drawdown (5Y) Largest decline over 5 years	-49.11%	-82.21%	+33.10%
Max Drawdown (10Y) Largest decline over 10 years	-49.67%	—	—
Current Drawdown Current decline from peak	-75.12%	-99.81%	+24.69%
Average Drawdown Average peak-to-trough decline	-58.44%	-96.43%	+37.99%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.88%	26.33%	-18.45%

Volatility

ALPMY vs. DCTH - Volatility Comparison

The current volatility for Astellas Pharma Inc (ALPMY) is 9.83%, while Delcath Systems, Inc. (DCTH) has a volatility of 13.30%. This indicates that ALPMY experiences smaller price fluctuations and is considered to be less risky than DCTH based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ALPMY	DCTH	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.83%	13.30%	-3.47%
Volatility (6M) Calculated over the trailing 6-month period	22.43%	32.57%	-10.14%
Volatility (1Y) Calculated over the trailing 1-year period	28.73%	49.63%	-20.90%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.42%	73.00%	-47.58%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.59%	109.86%	-84.27%

Dividends

ALPMY vs. DCTH - Dividend Comparison

Neither ALPMY nor DCTH has paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016
ALPMY Astellas Pharma Inc	0.00%	1.93%	2.56%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	1.20%	2.18%
DCTH Delcath Systems, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both ALPMY and DCTH in my portfolio?

ALPMY and DCTH have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ALPMY or DCTH?

DCTH has higher volatility (13.30%) compared to ALPMY (9.83%). In terms of maximum drawdown, ALPMY dropped -83.67% vs DCTH's -99.96%.

Which has better risk-adjusted returns?

ALPMY currently has the higher Sharpe Ratio (1.61 vs -0.34), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.