DRDR.L vs. SBIO.L

Last updated Jun 5, 2026

DRDR.L (iShares Healthcare Innovation UCITS ETF USD (Acc)) and SBIO.L (Invesco Nasdaq Biotech UCITS ETF) are both Health & Biotech Equities funds - DRDR.L tracks the MSCI World/Health Care NR USD while SBIO.L tracks the NASDAQ Biotechnology TR USD. Both are passively managed. Over the past 5 years, DRDR.L returned -0.91%/yr vs 5.79%/yr for SBIO.L. Their correlation of 0.82 suggests significant overlap in exposure. Both charge a 0.40% expense ratio.

Performance

DRDR.L vs. SBIO.L - Performance Comparison

The chart below illustrates the hypothetical performance of a £10,000 investment in iShares Healthcare Innovation UCITS ETF USD (Acc) (DRDR.L) and Invesco Nasdaq Biotech UCITS ETF (SBIO.L). The values are adjusted to include any dividend payments, if applicable.

Different Trading Currencies

DRDR.L is traded in GBp, while SBIO.L is traded in USD. To make them comparable, the SBIO.L values have been converted to GBp using the latest available exchange rates.

Returns By Period

In the year-to-date period, DRDR.L achieves a 1.01% return, which is significantly lower than SBIO.L's 4.76% return.

DRDR.L

• 1D: 3.48%
• 1M: 6.16%
• YTD: 1.01%
• 6M: -0.48%
• 1Y: 21.74%
• 3Y*: 3.43%
• 5Y*: -0.91%
• 10Y*: —

SBIO.L

• 1D: 3.10%
• 1M: 1.84%
• YTD: 4.76%
• 6M: 2.11%
• 1Y: 42.70%
• 3Y*: 10.15%
• 5Y*: 5.79%
• 10Y*: 8.29%

*Multi-year figures are annualized to reflect compound growth (CAGR)

DRDR.L vs. SBIO.L - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
DRDR.L iShares Healthcare Innovation UCITS ETF USD (Acc)	1.01%	10.25%	2.62%	-2.51%	-14.93%	-5.21%	48.69%	8.88%	2.12%	23.69%
SBIO.L Invesco Nasdaq Biotech UCITS ETF	4.76%	23.42%	-0.28%	0.83%	-1.37%	0.45%	23.61%	20.76%	-6.08%	10.95%

Correlation

The correlation between DRDR.L and SBIO.L is 0.81, indicating a strong positive relationship between their price movements. Combining them offers limited diversification - they tend to fall together during downturns.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.81
Correlation (3Y) Calculated over the trailing 3-year period	0.83
Correlation (5Y) Calculated over the trailing 5-year period	0.82
Correlation (All Time) Calculated using the full available price history since Sep 13, 2016	0.82

The correlation between DRDR.L and SBIO.L has been stable across timeframes, ranging from 0.81 to 0.83 - a consistent structural relationship.

DRDR.L vs. SBIO.L - Sectors Allocation Comparison

Sectors	DRDR.L	SBIO.L
Healthcare	98.0%	100.0%
Technology	1.2%	-
Industrials	0.4%	-
Basic Materials	0.4%	-
Financial Services	0.2%	-
Consumer Defensive	0.1%	-
Communication Services	-	-
Consumer Cyclical	-	-
Energy	-	-
Real Estate	-	-
Utilities	-	-

Return for Risk

DRDR.L vs. SBIO.L — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

DRDR.L

DRDR.L Risk / Return Rank: 37
DRDR.L Sharpe Ratio Rank: 40
DRDR.L Sortino Ratio Rank: 42
DRDR.L Omega Ratio Rank: 37
DRDR.L Calmar Ratio Rank: 36
DRDR.L Martin Ratio Rank: 30

SBIO.L

SBIO.L Risk / Return Rank: 72
SBIO.L Sharpe Ratio Rank: 64
SBIO.L Sortino Ratio Rank: 66
SBIO.L Omega Ratio Rank: 57
SBIO.L Calmar Ratio Rank: 89
SBIO.L Martin Ratio Rank: 83

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

DRDR.L vs. SBIO.L - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF USD (Acc) (DRDR.L) and Invesco Nasdaq Biotech UCITS ETF (SBIO.L). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	DRDR.L	SBIO.L	Difference
Sharpe ratio: Return per unit of total volatility	1.39	2.16	-0.77
Sortino ratio: Return per unit of downside risk	2.07	2.99	-0.92
Omega ratio: Gain probability vs. loss probability	1.24	1.36	-0.12
Calmar ratio: Return relative to maximum drawdown	1.73	5.97	-4.24
Martin ratio: Return relative to average drawdown	4.35	17.07	-12.72
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

DRDR.L vs. SBIO.L - Sharpe Ratio Comparison

The current DRDR.L Sharpe Ratio is 1.39, which is lower than the SBIO.L Sharpe Ratio of 2.16. The chart below compares the historical Sharpe Ratios of DRDR.L and SBIO.L, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	DRDR.L	SBIO.L	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.39	2.16	-0.77
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.05	0.28	-0.33
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.37	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.34	0.33	+0.02

Drawdowns

DRDR.L vs. SBIO.L - Drawdown Comparison

The maximum DRDR.L drawdown since its inception was -38.49%, which is greater than SBIO.L's maximum drawdown of -34.90%. Use the drawdown chart below to compare losses from any high point for DRDR.L and SBIO.L.

Drawdown Indicators

	DRDR.L	SBIO.L	Difference
Max Drawdown Largest peak-to-trough decline	-38.49%	-34.90%	-3.59%
Max Drawdown (1Y) Largest decline over 1 year	-12.51%	-7.11%	-5.40%
Max Drawdown (3Y) Largest decline over 3 years	-22.38%	-26.49%	+4.11%
Max Drawdown (5Y) Largest decline over 5 years	-35.81%	-30.92%	-4.89%
Max Drawdown (10Y) Largest decline over 10 years	—	-30.92%	—
Current Drawdown Current decline from peak	-16.88%	-2.14%	-14.74%
Average Drawdown Average peak-to-trough decline	-15.17%	-10.64%	-4.53%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.98%	2.49%	+2.49%

Volatility

DRDR.L vs. SBIO.L - Volatility Comparison

The current volatility for iShares Healthcare Innovation UCITS ETF USD (Acc) (DRDR.L) is 4.79%, while Invesco Nasdaq Biotech UCITS ETF (SBIO.L) has a volatility of 6.73%. This indicates that DRDR.L experiences smaller price fluctuations and is considered to be less risky than SBIO.L based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DRDR.L	SBIO.L	Difference
Volatility (1M) Calculated over the trailing 1-month period	4.79%	6.73%	-1.94%
Volatility (6M) Calculated over the trailing 6-month period	11.52%	15.04%	-3.52%
Volatility (1Y) Calculated over the trailing 1-year period	15.56%	19.68%	-4.12%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	17.52%	20.81%	-3.29%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	18.58%	22.49%	-3.91%

DRDR.L vs. SBIO.L - Expense Ratio Comparison

Both DRDR.L and SBIO.L have an expense ratio of 0.40%.

Dividends

DRDR.L vs. SBIO.L - Dividend Comparison

Neither DRDR.L nor SBIO.L has paid dividends to shareholders.

Tickers have no history of dividend payments

Frequently Asked Questions

Can I hold both DRDR.L and SBIO.L in my portfolio?

DRDR.L and SBIO.L have a correlation of 0.81, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, DRDR.L or SBIO.L?

Both ETFs have the same 0.40% expense ratio. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, DRDR.L or SBIO.L?

DRDR.L and SBIO.L have the same expense ratio: 0.40% per year.

What is the main difference between DRDR.L and SBIO.L?

DRDR.L tracks MSCI World/Health Care NR USD, while SBIO.L tracks NASDAQ Biotechnology TR USD. They also come from different issuers: iShares and Invesco.