CNTA vs. ARCT

Last updated Jun 23, 2026

CNTA (Centessa Pharmaceuticals Limited) and ARCT (Arcturus Therapeutics Holdings Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, CNTA returned 11.05%/yr vs -26.64%/yr for ARCT. At a 0.26 correlation, their price movements are largely independent.

Performance

CNTA vs. ARCT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Centessa Pharmaceuticals Limited (CNTA) and Arcturus Therapeutics Holdings Inc. (ARCT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CNTA achieves a 60.66% return, which is significantly higher than ARCT's 17.94% return.

CNTA

• 1D: 0.40%
• 1M: 1.08%
• YTD: 60.66%
• 6M: 58.31%
• 1Y: 223.25%
• 3Y*: 82.59%
• 5Y*: 11.05%
• 10Y*: —

ARCT

• 1D: -3.98%
• 1M: 2.84%
• YTD: 17.94%
• 6M: 9.71%
• 1Y: -41.17%
• 3Y*: -32.91%
• 5Y*: -26.64%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CNTA vs. ARCT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
CNTA Centessa Pharmaceuticals Limited	60.66%	49.31%	110.43%	156.77%	-72.47%	-44.40%
ARCT Arcturus Therapeutics Holdings Inc.	17.94%	-63.88%	-46.18%	85.91%	-54.17%	26.88%

Correlation

The correlation between CNTA and ARCT is 0.11, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.11
Correlation (3Y) Calculated over the trailing 3-year period	0.26
Correlation (5Y) Calculated over the trailing 5-year period	0.25
Correlation (All Time) Calculated using the full available price history since May 28, 2021	0.26

The correlation between CNTA and ARCT shifts across timeframes, from 0.11 (1 year) to 0.26 (3 years), reflecting how their relationship changes across market environments.

Fundamentals

EPS CNTA : -$1.81 ARCT : -$1.81
PS Ratio CNTA : 358.73 ARCT : 4.25
Total Revenue (TTM) CNTA : $15.00M ARCT : $46.80M
Gross Profit (TTM) CNTA : $15.00M ARCT : $40.72M
EBITDA (TTM) CNTA : -$227.27M ARCT : -$84.61M

Return for Risk

CNTA vs. ARCT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CNTA

CNTA Risk / Return Rank: 97
CNTA Sharpe Ratio Rank: 96
CNTA Sortino Ratio Rank: 98
CNTA Omega Ratio Rank: 97
CNTA Calmar Ratio Rank: 97
CNTA Martin Ratio Rank: 97

ARCT

ARCT Risk / Return Rank: 26
ARCT Sharpe Ratio Rank: 22
ARCT Sortino Ratio Rank: 29
ARCT Omega Ratio Rank: 29
ARCT Calmar Ratio Rank: 22
ARCT Martin Ratio Rank: 28

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CNTA vs. ARCT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Centessa Pharmaceuticals Limited (CNTA) and Arcturus Therapeutics Holdings Inc. (ARCT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	CNTA	ARCT	Difference
Sharpe ratio: Return per unit of total volatility	3.40	-0.45	+3.85
Sortino ratio: Return per unit of downside risk	5.28	-0.07	+5.35
Omega ratio: Gain probability vs. loss probability	1.69	0.99	+0.70
Calmar ratio: Return relative to maximum drawdown	8.52	-0.55	+9.07
Martin ratio: Return relative to average drawdown	23.60	-0.75	+24.35

CNTA vs. ARCT - Sharpe Ratio Comparison

The current CNTA Sharpe Ratio is 3.40, which is higher than the ARCT Sharpe Ratio of -0.45. The chart below compares the historical Sharpe Ratios of CNTA and ARCT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

CNTA vs. ARCT - Drawdown Comparison

The maximum CNTA drawdown since its inception was -88.19%, smaller than the maximum ARCT drawdown of -95.23%. Use the drawdown chart below to compare losses from any high point for CNTA and ARCT.

Drawdown Indicators

	CNTA	ARCT	Difference
Max Drawdown Largest peak-to-trough decline	-88.19%	-95.23%	+7.04%
Max Drawdown (1Y) Largest decline over 1 year	-26.38%	-74.53%	+48.15%
Max Drawdown (3Y) Largest decline over 3 years	-43.72%	-86.71%	+42.99%
Max Drawdown (5Y) Largest decline over 5 years	-87.63%	-89.87%	+2.24%
Current Drawdown Current decline from peak	0.00%	-94.15%	+94.15%
Average Drawdown Average peak-to-trough decline	-51.58%	-73.10%	+21.52%
Ulcer Index Depth and duration of drawdowns from previous peaks	9.51%	54.85%	-45.34%

Volatility

CNTA vs. ARCT - Volatility Comparison

The current volatility for Centessa Pharmaceuticals Limited (CNTA) is 0.96%, while Arcturus Therapeutics Holdings Inc. (ARCT) has a volatility of 17.09%. This indicates that CNTA experiences smaller price fluctuations and is considered to be less risky than ARCT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CNTA	ARCT	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.96%	17.09%	-16.13%
Volatility (6M) Calculated over the trailing 6-month period	42.83%	39.78%	+3.05%
Volatility (1Y) Calculated over the trailing 1-year period	66.21%	92.79%	-26.58%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	71.70%	91.80%	-20.10%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	72.09%	102.00%	-29.91%

Dividends

CNTA vs. ARCT - Dividend Comparison

Neither CNTA nor ARCT has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both CNTA and ARCT in my portfolio?

CNTA and ARCT have a correlation of 0.11, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CNTA or ARCT?

ARCT has higher volatility (17.09%) compared to CNTA (0.96%). In terms of maximum drawdown, CNTA dropped -88.19% vs ARCT's -95.23%.

Which has better risk-adjusted returns?

CNTA currently has the higher Sharpe Ratio (3.40 vs -0.45), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.