CGON vs. AGNC

Last updated Jun 3, 2026

CGON (CG Oncology, Inc) and AGNC (AGNC Investment Corp.) are both stocks. CGON operates in Biotechnology (Healthcare), while AGNC operates in REIT - Mortgage (Real Estate). Over the past year, CGON returned 108.84% vs 32.91% for AGNC. At a 0.30 correlation, their price movements are largely independent.

Performance

CGON vs. AGNC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in CG Oncology, Inc (CGON) and AGNC Investment Corp. (AGNC). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CGON achieves a 33.74% return, which is significantly higher than AGNC's 0.57% return.

CGON

• 1D: -6.25%
• 1M: -16.21%
• YTD: 33.74%
• 6M: 34.23%
• 1Y: 108.84%
• 3Y*: —
• 5Y*: —
• 10Y*: —

AGNC

• 1D: -0.29%
• 1M: -5.69%
• YTD: 0.57%
• 6M: 4.23%
• 1Y: 32.91%
• 3Y*: 18.80%
• 5Y*: 1.66%
• 10Y*: 6.24%

*Multi-year figures are annualized to reflect compound growth (CAGR)

CGON vs. AGNC - Yearly Performance Comparison

	2026 (YTD)	2025	2024
CGON CG Oncology, Inc	33.74%	44.77%	-22.84%
AGNC AGNC Investment Corp.	0.57%	34.92%	8.79%

Correlation

The correlation between CGON and AGNC is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.24
Correlation (All Time) Calculated using the full available price history since Jan 26, 2024	0.30

Fundamentals

Market Cap CGON : $4.69B AGNC : $11.45B
EPS CGON : -$1.61 AGNC : $1.33
PS Ratio CGON : 861.75 AGNC : 4.70
PB Ratio CGON : 4.30 AGNC : 1.12
Total Revenue (TTM) CGON : $5.07M AGNC : $2.33B
Gross Profit (TTM) CGON : -$2.54M AGNC : $2.30B
EBITDA (TTM) CGON : -$191.51M AGNC : $3.72B

Return for Risk

CGON vs. AGNC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CGON

CGON Risk / Return Rank: 87
CGON Sharpe Ratio Rank: 86
CGON Sortino Ratio Rank: 87
CGON Omega Ratio Rank: 82
CGON Calmar Ratio Rank: 90
CGON Martin Ratio Rank: 93

AGNC

AGNC Risk / Return Rank: 77
AGNC Sharpe Ratio Rank: 84
AGNC Sortino Ratio Rank: 80
AGNC Omega Ratio Rank: 78
AGNC Calmar Ratio Rank: 71
AGNC Martin Ratio Rank: 75

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CGON vs. AGNC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for CG Oncology, Inc (CGON) and AGNC Investment Corp. (AGNC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CGON	AGNC	Difference
Sharpe ratio Return per unit of total volatility	1.93	1.71	+0.22
Sortino ratio Return per unit of downside risk	2.92	2.35	+0.57
Omega ratio Gain probability vs. loss probability	1.33	1.29	+0.04
Calmar ratio Return relative to maximum drawdown	4.68	1.67	+3.01
Martin ratio Return relative to average drawdown	15.68	5.11	+10.57
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CGON vs. AGNC - Sharpe Ratio Comparison

The current CGON Sharpe Ratio is 1.93, which is comparable to the AGNC Sharpe Ratio of 1.71. The chart below compares the historical Sharpe Ratios of CGON and AGNC, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	CGON	AGNC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.93	1.71	+0.22
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.06	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.25	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.29	0.43	-0.13

Drawdowns

CGON vs. AGNC - Drawdown Comparison

The maximum CGON drawdown since its inception was -67.47%, which is greater than AGNC's maximum drawdown of -54.56%. Use the drawdown chart below to compare losses from any high point for CGON and AGNC.

Drawdown Indicators

	CGON	AGNC	Difference
Max Drawdown Largest peak-to-trough decline	-67.47%	-54.56%	-12.91%
Max Drawdown (1Y) Largest decline over 1 year	-24.96%	-18.71%	-6.25%
Max Drawdown (3Y) Largest decline over 3 years	—	-31.04%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-54.56%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-54.56%	—
Current Drawdown Current decline from peak	-24.96%	-11.41%	-13.55%
Average Drawdown Average peak-to-trough decline	-25.93%	-13.57%	-12.36%
Ulcer Index Depth and duration of drawdowns from previous peaks	7.45%	6.12%	+1.33%

Volatility

CGON vs. AGNC - Volatility Comparison

CG Oncology, Inc (CGON) has a higher volatility of 14.68% compared to AGNC Investment Corp. (AGNC) at 5.41%. This indicates that CGON's price experiences larger fluctuations and is considered to be riskier than AGNC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CGON	AGNC	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.68%	5.41%	+9.27%
Volatility (6M) Calculated over the trailing 6-month period	41.79%	15.86%	+25.93%
Volatility (1Y) Calculated over the trailing 1-year period	56.79%	19.40%	+37.39%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	64.24%	25.81%	+38.43%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	64.24%	25.39%	+38.85%

Dividends

CGON vs. AGNC - Dividend Comparison

CGON has not paid dividends to shareholders, while AGNC's dividend yield for the trailing twelve months is around 14.12%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AGNC AGNC Investment Corp.	14.12%	13.43%	15.64%	14.68%	13.91%	9.57%	10.00%	11.31%	12.31%	10.70%	12.69%	14.30%
CGON CG Oncology, Inc	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both CGON and AGNC in my portfolio?

CGON and AGNC have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CGON or AGNC?

CGON has higher volatility (14.68%) compared to AGNC (5.41%). In terms of maximum drawdown, CGON dropped -67.47% vs AGNC's -54.56%.

Which has better risk-adjusted returns?

CGON currently has the higher Sharpe Ratio (1.93 vs 1.71), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.