CCCC vs. SRRK

Last updated Jun 9, 2026

CCCC (C4 Therapeutics, Inc.) and SRRK (Scholar Rock Holding Corporation) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, CCCC returned -38.85%/yr vs 8.97%/yr for SRRK. At a 0.35 correlation, their price movements are largely independent.

Performance

CCCC vs. SRRK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in C4 Therapeutics, Inc. (CCCC) and Scholar Rock Holding Corporation (SRRK). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CCCC achieves a 87.96% return, which is significantly higher than SRRK's -0.57% return.

CCCC

• 1D: -6.75%
• 1M: 21.69%
• YTD: 87.96%
• 6M: 41.34%
• 1Y: 107.51%
• 3Y*: 1.04%
• 5Y*: -38.85%
• 10Y*: —

SRRK

• 1D: -1.13%
• 1M: -9.49%
• YTD: -0.57%
• 6M: -3.20%
• 1Y: 27.96%
• 3Y*: 84.27%
• 5Y*: 8.97%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CCCC vs. SRRK - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
CCCC C4 Therapeutics, Inc.	87.96%	-46.94%	-36.28%	-4.24%	-81.68%	-2.81%	29.97%
SRRK Scholar Rock Holding Corporation	-0.57%	1.92%	129.89%	107.73%	-63.57%	-48.82%	215.33%

Correlation

The correlation between CCCC and SRRK is 0.19, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.19
Correlation (3Y) Calculated over the trailing 3-year period	0.30
Correlation (5Y) Calculated over the trailing 5-year period	0.37
Correlation (All Time) Calculated using the full available price history since Oct 5, 2020	0.35

The correlation between CCCC and SRRK shifts across timeframes, from 0.19 (1 year) to 0.37 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap CCCC : $452.61M SRRK : $5.57B
EPS CCCC : -$1.18 SRRK : -$3.49
PB Ratio CCCC : 1.93 SRRK : 20.20
Total Revenue (TTM) CCCC : $28.71M SRRK : $0.00
Gross Profit (TTM) CCCC : $26.90M SRRK : -$1.27M
EBITDA (TTM) CCCC : -$107.31M SRRK : -$394.71M

Return for Risk

CCCC vs. SRRK — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CCCC

CCCC Risk / Return Rank: 75
CCCC Sharpe Ratio Rank: 74
CCCC Sortino Ratio Rank: 80
CCCC Omega Ratio Rank: 74
CCCC Calmar Ratio Rank: 76
CCCC Martin Ratio Rank: 73

SRRK

SRRK Risk / Return Rank: 59
SRRK Sharpe Ratio Rank: 58
SRRK Sortino Ratio Rank: 61
SRRK Omega Ratio Rank: 57
SRRK Calmar Ratio Rank: 60
SRRK Martin Ratio Rank: 61

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CCCC vs. SRRK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for C4 Therapeutics, Inc. (CCCC) and Scholar Rock Holding Corporation (SRRK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CCCC	SRRK	Difference
Sharpe ratio: Return per unit of total volatility	1.07	0.43	+0.64
Sortino ratio: Return per unit of downside risk	2.22	1.20	+1.02
Omega ratio: Gain probability vs. loss probability	1.24	1.14	+0.10
Calmar ratio: Return relative to maximum drawdown	2.08	0.81	+1.27
Martin ratio: Return relative to average drawdown	4.02	1.92	+2.10
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CCCC vs. SRRK - Sharpe Ratio Comparison

The current CCCC Sharpe Ratio is 1.07, which is higher than the SRRK Sharpe Ratio of 0.43. The chart below compares the historical Sharpe Ratios of CCCC and SRRK, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	CCCC	SRRK	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.07	0.43	+0.64
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.33	0.05	-0.38
Sharpe Ratio (All Time) Calculated using the full available price history	-0.26	0.09	-0.35

Drawdowns

CCCC vs. SRRK - Drawdown Comparison

The maximum CCCC drawdown since its inception was -97.82%, which is greater than SRRK's maximum drawdown of -93.15%. Use the drawdown chart below to compare losses from any high point for CCCC and SRRK.

Drawdown Indicators

	CCCC	SRRK	Difference
Max Drawdown Largest peak-to-trough decline	-97.82%	-93.15%	-4.67%
Max Drawdown (1Y) Largest decline over 1 year	-52.10%	-34.86%	-17.24%
Max Drawdown (3Y) Largest decline over 3 years	-90.00%	-65.21%	-24.79%
Max Drawdown (5Y) Largest decline over 5 years	-97.82%	-88.96%	-8.86%
Current Drawdown Current decline from peak	-92.89%	-35.61%	-57.28%
Average Drawdown Average peak-to-trough decline	-71.93%	-56.44%	-15.49%
Ulcer Index Depth and duration of drawdowns from previous peaks	26.91%	14.61%	+12.30%

Volatility

CCCC vs. SRRK - Volatility Comparison

C4 Therapeutics, Inc. (CCCC) has a higher volatility of 33.23% compared to Scholar Rock Holding Corporation (SRRK) at 13.58%. This indicates that CCCC's price experiences larger fluctuations and is considered to be riskier than SRRK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CCCC	SRRK	Difference
Volatility (1M) Calculated over the trailing 1-month period	33.23%	13.58%	+19.65%
Volatility (6M) Calculated over the trailing 6-month period	64.03%	35.86%	+28.17%
Volatility (1Y) Calculated over the trailing 1-year period	101.70%	65.55%	+36.15%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	117.54%	180.23%	-62.69%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	113.15%	157.72%	-44.57%

Dividends

CCCC vs. SRRK - Dividend Comparison

Neither CCCC nor SRRK has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both CCCC and SRRK in my portfolio?

CCCC and SRRK have a correlation of 0.19, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CCCC or SRRK?

CCCC has higher volatility (33.23%) compared to SRRK (13.58%). In terms of maximum drawdown, CCCC dropped -97.82% vs SRRK's -93.15%.

Which has better risk-adjusted returns?

CCCC currently has the higher Sharpe Ratio (1.07 vs 0.43), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.