CANC vs. HEAL

Last updated Jun 24, 2026

CANC (Tema Oncology ETF) and HEAL (Global X HealthTech ETF) are both Health & Biotech Equities funds. CANC is actively managed, while HEAL is passively managed. Over the past 3 years, CANC returned 132.65%/yr vs -8.12%/yr for HEAL. At a 0.43 correlation, their price movements are largely independent. CANC charges 0.75%/yr vs 0.50%/yr for HEAL.

Performance

CANC vs. HEAL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Tema Oncology ETF (CANC) and Global X HealthTech ETF (HEAL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, CANC achieves a 11.49% return, which is significantly higher than HEAL's -10.37% return.

CANC

• 1D: 1.64%
• 1M: 1.56%
• YTD: 11.49%
• 6M: 9.19%
• 1Y: 56.88%
• 3Y*: 132.65%
• 5Y*: —
• 10Y*: —

HEAL

• 1D: 1.49%
• 1M: 5.54%
• YTD: -10.37%
• 6M: -12.67%
• 1Y: -16.13%
• 3Y*: -8.12%
• 5Y*: -14.64%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CANC vs. HEAL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
CANC Tema Oncology ETF	11.49%	42.92%	-5.37%	510.51%	-85.34%	-55.35%
HEAL Global X HealthTech ETF	-10.37%	-0.62%	-2.87%	-12.61%	-29.99%	-6.71%

Correlation

The correlation between CANC and HEAL is 0.45, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.45
Correlation (3Y) Calculated over the trailing 3-year period	0.52
Correlation (All Time) Calculated using the full available price history since Sep 30, 2021	0.43

The correlation between CANC and HEAL has been stable across timeframes, ranging from 0.43 to 0.52 - a consistent structural relationship.

CANC vs. HEAL - Sectors Allocation Comparison

Sectors	CANC	HEAL
Healthcare	100.0%	96.5%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	-
Industrials	-	-
Real Estate	-	-
Technology	-	2.9%
Utilities	-	-

Return for Risk

CANC vs. HEAL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CANC

CANC Risk / Return Rank: 85
CANC Sharpe Ratio Rank: 85
CANC Sortino Ratio Rank: 86
CANC Omega Ratio Rank: 74
CANC Calmar Ratio Rank: 93
CANC Martin Ratio Rank: 85

HEAL

HEAL Risk / Return Rank: 4
HEAL Sharpe Ratio Rank: 3
HEAL Sortino Ratio Rank: 3
HEAL Omega Ratio Rank: 4
HEAL Calmar Ratio Rank: 5
HEAL Martin Ratio Rank: 4

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CANC vs. HEAL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Tema Oncology ETF (CANC) and Global X HealthTech ETF (HEAL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	CANC	HEAL	Difference
Sharpe ratio: Return per unit of total volatility	2.52	-0.73	+3.24
Sortino ratio: Return per unit of downside risk	3.54	-0.95	+4.49
Omega ratio: Gain probability vs. loss probability	1.40	0.90	+0.51
Calmar ratio: Return relative to maximum drawdown	6.15	-0.53	+6.67
Martin ratio: Return relative to average drawdown	16.71	-1.01	+17.72

CANC vs. HEAL - Sharpe Ratio Comparison

The current CANC Sharpe Ratio is 2.52, which is higher than the HEAL Sharpe Ratio of -0.73. The chart below compares the historical Sharpe Ratios of CANC and HEAL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

CANC vs. HEAL - Drawdown Comparison

The maximum CANC drawdown since its inception was -97.53%, which is greater than HEAL's maximum drawdown of -65.76%. Use the drawdown chart below to compare losses from any high point for CANC and HEAL.

Drawdown Indicators

	CANC	HEAL	Difference
Max Drawdown Largest peak-to-trough decline	-97.53%	-65.76%	-31.77%
Max Drawdown (1Y) Largest decline over 1 year	-9.30%	-30.71%	+21.41%
Max Drawdown (3Y) Largest decline over 3 years	-30.27%	-35.78%	+5.51%
Max Drawdown (5Y) Largest decline over 5 years	—	-60.36%	—
Current Drawdown Current decline from peak	-53.78%	-61.31%	+7.53%
Average Drawdown Average peak-to-trough decline	-72.94%	-43.20%	-29.74%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.41%	15.98%	-12.57%

Volatility

CANC vs. HEAL - Volatility Comparison

The current volatility for Tema Oncology ETF (CANC) is 6.60%, while Global X HealthTech ETF (HEAL) has a volatility of 7.26%. This indicates that CANC experiences smaller price fluctuations and is considered to be less risky than HEAL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CANC	HEAL	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.60%	7.26%	-0.66%
Volatility (6M) Calculated over the trailing 6-month period	16.94%	16.63%	+0.31%
Volatility (1Y) Calculated over the trailing 1-year period	22.72%	22.43%	+0.29%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	278.65%	26.46%	+252.19%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	278.65%	26.28%	+252.37%

CANC vs. HEAL - Expense Ratio Comparison

CANC has a 0.75% expense ratio, which is higher than HEAL's 0.50% expense ratio.

Dividends

CANC vs. HEAL - Dividend Comparison

CANC's dividend yield for the trailing twelve months is around 0.05%, less than HEAL's 0.37% yield.

Position	TTM	2025	2024	2023	2022	2021	2020
CANC Tema Oncology ETF	0.05%	0.06%	3.00%	0.56%	0.00%	0.00%	0.00%
HEAL Global X HealthTech ETF	0.37%	0.33%	0.00%	0.00%	0.00%	0.00%	0.03%

Frequently Asked Questions

Can I hold both CANC and HEAL in my portfolio?

CANC and HEAL have a correlation of 0.45, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, CANC or HEAL?

HEAL has higher volatility (7.26%) compared to CANC (6.60%). In terms of maximum drawdown, CANC dropped -97.53% vs HEAL's -65.76%.

Which ETF is better, CANC or HEAL?

On 3-year performance, CANC leads with 132.65% vs -8.12% for HEAL. On fees, HEAL is cheaper at 0.50% per year. On volatility, CANC has been the lower-risk option at 6.60%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, CANC or HEAL?

Over the 3-year period, CANC has performed better with a 132.65% return vs -8.12%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, CANC or HEAL?

HEAL is cheaper with a 0.50% expense ratio, compared with 0.75% for CANC.

Which ETF pays a higher dividend yield, CANC or HEAL?

HEAL has the higher dividend yield at 0.37%, compared with 0.05% for CANC.

What is the main difference between CANC and HEAL?

They also come from different issuers: Tema and Global X. Their fees differ too: 0.75% for CANC and 0.50% for HEAL.

Which has better risk-adjusted returns?

CANC currently has the higher Sharpe Ratio (2.52 vs -0.73), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.