CANC vs. BTEC

Last updated Jun 4, 2026

CANC (Tema Oncology ETF) and BTEC (Principal Healthcare Innovators Index ETF) are both Health & Biotech Equities funds. CANC is actively managed, while BTEC is passively managed. CANC charges 0.75%/yr vs 0.42%/yr for BTEC.

Performance

CANC vs. BTEC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Tema Oncology ETF (CANC) and Principal Healthcare Innovators Index ETF (BTEC). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

CANC

• 1D: 0.08%
• 1M: -3.73%
• YTD: 4.82%
• 6M: 3.86%
• 1Y: 47.37%
• 3Y*: 107.76%
• 5Y*: —
• 10Y*: —

BTEC

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

CANC vs. BTEC - Yearly Performance Comparison

	2026 (YTD)
CANC Tema Oncology ETF	-0.51%
BTEC Principal Healthcare Innovators Index ETF	0.00%

CANC vs. BTEC - Sectors Allocation Comparison

Sectors	CANC	BTEC
Healthcare	100.0%	99.4%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	-
Industrials	-	0.6%
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

CANC vs. BTEC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CANC

CANC Risk / Return Rank: 69
CANC Sharpe Ratio Rank: 61
CANC Sortino Ratio Rank: 64
CANC Omega Ratio Rank: 54
CANC Calmar Ratio Rank: 90
CANC Martin Ratio Rank: 77

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CANC vs. BTEC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Tema Oncology ETF (CANC) and Principal Healthcare Innovators Index ETF (BTEC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CANC	BTEC	Difference
Sharpe ratio: Return per unit of total volatility	2.06	—	—
Sortino ratio: Return per unit of downside risk	2.96	—	—
Omega ratio: Gain probability vs. loss probability	1.34	—	—
Calmar ratio: Return relative to maximum drawdown	5.49	—	—
Martin ratio: Return relative to average drawdown	14.62	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	CANC	BTEC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.06	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.04	—	—

Drawdowns

CANC vs. BTEC - Drawdown Comparison

The maximum CANC drawdown since its inception was -97.53%, which is greater than BTEC's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for CANC and BTEC.

Drawdown Indicators

	CANC	BTEC	Difference
Max Drawdown Largest peak-to-trough decline	-97.53%	0.00%	-97.53%
Max Drawdown (1Y) Largest decline over 1 year	-8.67%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-30.27%	—	—
Current Drawdown Current decline from peak	-56.55%	0.00%	-56.55%
Average Drawdown Average peak-to-trough decline	-73.19%	0.00%	-73.19%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.25%	—	—

Volatility

Volatility by Period

	CANC	BTEC	Difference
Volatility (1M) Calculated over the trailing 1-month period	6.26%	—	—
Volatility (6M) Calculated over the trailing 6-month period	16.69%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	23.11%	0.00%	+23.11%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	280.27%	0.00%	+280.27%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	280.27%	0.00%	+280.27%

CANC vs. BTEC - Expense Ratio Comparison

CANC has a 0.75% expense ratio, which is higher than BTEC's 0.42% expense ratio.

Dividends

CANC vs. BTEC - Dividend Comparison

CANC's dividend yield for the trailing twelve months is around 0.05%, while BTEC has not paid dividends to shareholders.

Position	TTM	2025	2024	2023
BTEC Principal Healthcare Innovators Index ETF	0.00%	0.00%	0.00%	0.00%
CANC Tema Oncology ETF	0.05%	0.06%	3.00%	0.56%

Frequently Asked Questions

Which ETF is better, CANC or BTEC?

On fees, BTEC is cheaper at 0.42% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, CANC or BTEC?

BTEC is cheaper with a 0.42% expense ratio, compared with 0.75% for CANC.

Which ETF pays a higher dividend yield, CANC or BTEC?

CANC has the higher dividend yield at 0.05%, compared with 0.00% for BTEC.

What is the main difference between CANC and BTEC?

They also come from different issuers: Tema and Principal. Their fees differ too: 0.75% for CANC and 0.42% for BTEC.