BIOY vs. TLTX

Last updated Jul 1, 2026

BIOY (GraniteShares YieldBOOST Biotech ETF) and TLTX (Global X Treasury Bond Enhanced Income ETF) are both exchange-traded funds - BIOY is a Derivative Income fund actively managed by GraniteShares, while TLTX is a Government Bonds fund actively managed by Global X. Both are actively managed. At a 0.24 correlation, their price movements are largely independent. BIOY charges 1.07%/yr vs 0.29%/yr for TLTX.

Performance

BIOY vs. TLTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in GraniteShares YieldBOOST Biotech ETF (BIOY) and Global X Treasury Bond Enhanced Income ETF (TLTX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

BIOY

• 1D: 0.30%
• 1M: 1.11%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

TLTX

• 1D: -0.33%
• 1M: 2.01%
• YTD: 1.80%
• 6M: 1.57%
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

BIOY vs. TLTX - Yearly Performance Comparison

	2026 (YTD)
BIOY GraniteShares YieldBOOST Biotech ETF	0.99%
TLTX Global X Treasury Bond Enhanced Income ETF	1.97%

Correlation

The correlation between BIOY and TLTX is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (All Time) Calculated using the full available price history since May 5, 2026	0.24

Return for Risk

BIOY vs. TLTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for GraniteShares YieldBOOST Biotech ETF (BIOY) and Global X Treasury Bond Enhanced Income ETF (TLTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Drawdowns

BIOY vs. TLTX - Drawdown Comparison

The maximum BIOY drawdown since its inception was -5.07%, smaller than the maximum TLTX drawdown of -6.35%. Use the drawdown chart below to compare losses from any high point for BIOY and TLTX.

Drawdown Indicators

	BIOY	TLTX	Difference
Max Drawdown Largest peak-to-trough decline	-5.07%	-6.35%	+1.28%
Current Drawdown Current decline from peak	-0.46%	-1.97%	+1.51%
Average Drawdown Average peak-to-trough decline	-2.16%	-2.28%	+0.12%

Volatility

Volatility by Period

	BIOY	TLTX	Difference
Volatility (1Y) Calculated over the trailing 1-year period	15.83%	9.21%	+6.62%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	15.83%	9.21%	+6.62%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	15.83%	9.21%	+6.62%

BIOY vs. TLTX - Expense Ratio Comparison

BIOY has a 1.07% expense ratio, which is higher than TLTX's 0.29% expense ratio.

Dividends

BIOY vs. TLTX - Dividend Comparison

BIOY's dividend yield for the trailing twelve months is around 9.46%, less than TLTX's 17.14% yield.

Position	TTM	2025
BIOY GraniteShares YieldBOOST Biotech ETF	9.46%	0.00%
TLTX Global X Treasury Bond Enhanced Income ETF	17.14%	7.54%

Frequently Asked Questions

Can I hold both BIOY and TLTX in my portfolio?

BIOY and TLTX have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which ETF is better, BIOY or TLTX?

On fees, TLTX is cheaper at 0.29% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, BIOY or TLTX?

TLTX is cheaper with a 0.29% expense ratio, compared with 1.07% for BIOY.

Which ETF pays a higher dividend yield, BIOY or TLTX?

TLTX has the higher dividend yield at 17.14%, compared with 9.46% for BIOY.

What is the main difference between BIOY and TLTX?

BIOY is categorized as Derivative Income, while TLTX is Government Bonds. They also come from different issuers: GraniteShares and Global X. Their fees differ too: 1.07% for BIOY and 0.29% for TLTX.