BBC vs. RSPH

Last updated Jun 4, 2026

BBC (Virtus LifeSci Biotech Clinical Trials ETF) and RSPH (Invesco S&P 500 Equal Weight Health Care ETF) are both Health & Biotech Equities funds - BBC tracks the LifeSci Biotechnology Clinical Trials Index while RSPH tracks the S&P 500 Equal Weighted / Health Care -SEC. Both are passively managed. Over the past 10 years, BBC returned 7.64%/yr vs 7.94%/yr for RSPH. A 0.57 correlation means they provide meaningful diversification when combined. BBC charges 0.79%/yr vs 0.40%/yr for RSPH.

Performance

BBC vs. RSPH - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Virtus LifeSci Biotech Clinical Trials ETF (BBC) and Invesco S&P 500 Equal Weight Health Care ETF (RSPH). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, BBC achieves a 8.64% return, which is significantly higher than RSPH's -2.71% return. Both investments have delivered pretty close results over the past 10 years, with BBC having a 7.64% annualized return and RSPH not far ahead at 7.94%.

BBC

• 1D: 0.43%
• 1M: -6.52%
• YTD: 8.64%
• 6M: 14.08%
• 1Y: 116.78%
• 3Y*: 19.99%
• 5Y*: -1.96%
• 10Y*: 7.64%

RSPH

• 1D: 0.81%
• 1M: 2.49%
• YTD: -2.71%
• 6M: -2.70%
• 1Y: 8.70%
• 3Y*: 3.21%
• 5Y*: 2.54%
• 10Y*: 7.94%

*Multi-year figures are annualized to reflect compound growth (CAGR)

BBC vs. RSPH - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
BBC Virtus LifeSci Biotech Clinical Trials ETF	8.64%	63.77%	-1.11%	-1.80%	-35.13%	-22.31%	30.32%	63.81%	-18.29%	57.85%
RSPH Invesco S&P 500 Equal Weight Health Care ETF	-2.71%	9.52%	-0.94%	3.95%	-9.40%	23.19%	18.83%	25.48%	-0.66%	23.70%

Correlation

The correlation between BBC and RSPH is 0.37, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.37
Correlation (3Y) Calculated over the trailing 3-year period	0.45
Correlation (5Y) Calculated over the trailing 5-year period	0.50
Correlation (10Y) Calculated over the trailing 10-year period	0.55
Correlation (All Time) Calculated using the full available price history since Dec 18, 2014	0.57

The correlation between BBC and RSPH shifts across timeframes, from 0.37 (1 year) to 0.57 (all time), reflecting how their relationship changes across market environments.

BBC vs. RSPH - Sectors Allocation Comparison

Sectors	BBC	RSPH
Healthcare	100.0%	98.5%
Basic Materials	-	-
Communication Services	-	-
Consumer Cyclical	-	-
Consumer Defensive	-	-
Energy	-	-
Financial Services	-	0.1%
Industrials	-	-
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

BBC vs. RSPH — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

BBC

BBC Risk / Return Rank: 89
BBC Sharpe Ratio Rank: 92
BBC Sortino Ratio Rank: 87
BBC Omega Ratio Rank: 77
BBC Calmar Ratio Rank: 95
BBC Martin Ratio Rank: 93

RSPH

RSPH Risk / Return Rank: 18
RSPH Sharpe Ratio Rank: 18
RSPH Sortino Ratio Rank: 18
RSPH Omega Ratio Rank: 17
RSPH Calmar Ratio Rank: 19
RSPH Martin Ratio Rank: 19

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

BBC vs. RSPH - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Virtus LifeSci Biotech Clinical Trials ETF (BBC) and Invesco S&P 500 Equal Weight Health Care ETF (RSPH). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	BBC	RSPH	Difference
Sharpe ratio Return per unit of total volatility	3.32	0.57	+2.76
Sortino ratio Return per unit of downside risk	3.98	0.91	+3.06
Omega ratio Gain probability vs. loss probability	1.46	1.11	+0.35
Calmar ratio Return relative to maximum drawdown	7.78	0.80	+6.97
Martin ratio Return relative to average drawdown	24.80	2.01	+22.78
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

BBC vs. RSPH - Sharpe Ratio Comparison

The current BBC Sharpe Ratio is 3.32, which is higher than the RSPH Sharpe Ratio of 0.57. The chart below compares the historical Sharpe Ratios of BBC and RSPH, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	BBC	RSPH	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	3.32	0.57	+2.76
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.05	0.16	-0.21
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.20	0.45	-0.25
Sharpe Ratio (All Time) Calculated using the full available price history	0.12	0.58	-0.46

Drawdowns

BBC vs. RSPH - Drawdown Comparison

The maximum BBC drawdown since its inception was -76.85%, which is greater than RSPH's maximum drawdown of -40.49%. Use the drawdown chart below to compare losses from any high point for BBC and RSPH.

Drawdown Indicators

	BBC	RSPH	Difference
Max Drawdown Largest peak-to-trough decline	-76.85%	-40.49%	-36.36%
Max Drawdown (1Y) Largest decline over 1 year	-15.10%	-10.87%	-4.23%
Max Drawdown (3Y) Largest decline over 3 years	-54.45%	-17.13%	-37.32%
Max Drawdown (5Y) Largest decline over 5 years	-72.44%	-21.95%	-50.49%
Max Drawdown (10Y) Largest decline over 10 years	-76.85%	-30.44%	-46.41%
Current Drawdown Current decline from peak	-30.27%	-6.83%	-23.44%
Average Drawdown Average peak-to-trough decline	-37.14%	-6.14%	-31.00%
Ulcer Index Depth and duration of drawdowns from previous peaks	4.73%	4.33%	+0.40%

Volatility

BBC vs. RSPH - Volatility Comparison

Virtus LifeSci Biotech Clinical Trials ETF (BBC) has a higher volatility of 10.93% compared to Invesco S&P 500 Equal Weight Health Care ETF (RSPH) at 3.87%. This indicates that BBC's price experiences larger fluctuations and is considered to be riskier than RSPH based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	BBC	RSPH	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.93%	3.87%	+7.06%
Volatility (6M) Calculated over the trailing 6-month period	26.43%	10.36%	+16.07%
Volatility (1Y) Calculated over the trailing 1-year period	35.50%	15.46%	+20.04%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	39.31%	16.26%	+23.05%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	37.74%	17.72%	+20.02%

BBC vs. RSPH - Expense Ratio Comparison

BBC has a 0.79% expense ratio, which is higher than RSPH's 0.40% expense ratio.

Dividends

BBC vs. RSPH - Dividend Comparison

BBC's dividend yield for the trailing twelve months is around 1.56%, more than RSPH's 0.73% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
BBC Virtus LifeSci Biotech Clinical Trials ETF	1.56%	1.70%	1.00%	0.34%	0.00%	0.00%	0.00%	0.00%	0.00%	2.09%	0.00%	0.51%
RSPH Invesco S&P 500 Equal Weight Health Care ETF	0.73%	0.70%	0.71%	0.66%	0.64%	0.50%	0.51%	0.54%	0.53%	0.47%	0.48%	0.49%

Frequently Asked Questions

Can I hold both BBC and RSPH in my portfolio?

BBC and RSPH have a correlation of 0.37, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, BBC or RSPH?

BBC has higher volatility (10.93%) compared to RSPH (3.87%). In terms of maximum drawdown, BBC dropped -76.85% vs RSPH's -40.49%.

Which ETF is better, BBC or RSPH?

On 10-year performance, RSPH leads with 7.94% vs 7.64% for BBC. On fees, RSPH is cheaper at 0.40% per year. On volatility, RSPH has been the lower-risk option at 3.87%. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF has performed better, BBC or RSPH?

Over the 10-year period, RSPH has performed better with a 7.94% return vs 7.64%. Past performance does not guarantee future results, so compare this with risk, fees, and fund exposure.

Which ETF is cheaper, BBC or RSPH?

RSPH is cheaper with a 0.40% expense ratio, compared with 0.79% for BBC.

Which ETF pays a higher dividend yield, BBC or RSPH?

BBC has the higher dividend yield at 1.56%, compared with 0.73% for RSPH.

What is the main difference between BBC and RSPH?

BBC tracks LifeSci Biotechnology Clinical Trials Index, while RSPH tracks S&P 500 Equal Weighted / Health Care -SEC. They also come from different issuers: Virtus Investment Partners and Invesco. Their fees differ too: 0.79% for BBC and 0.40% for RSPH.

Which has better risk-adjusted returns?

BBC currently has the higher Sharpe Ratio (3.32 vs 0.57), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.