ANIP vs. OCUL

Last updated Jun 23, 2026

ANIP (ANI Pharmaceuticals, Inc.) and OCUL (Ocular Therapeutix, Inc.) are both stocks. Both are in the Healthcare sector — ANIP in Drug Manufacturers - Specialty & Generic, OCUL in Biotechnology. Over the past 10 years, ANIP returned 4.02%/yr vs 6.79%/yr for OCUL. At a 0.31 correlation, their price movements are largely independent.

Performance

ANIP vs. OCUL - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ANI Pharmaceuticals, Inc. (ANIP) and Ocular Therapeutix, Inc. (OCUL). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ANIP achieves a 2.08% return, which is significantly higher than OCUL's -17.87% return. Over the past 10 years, ANIP has underperformed OCUL with an annualized return of 4.02%, while OCUL has yielded a comparatively higher 6.79% annualized return.

ANIP

• 1D: 1.37%
• 1M: -2.59%
• YTD: 2.08%
• 6M: -0.17%
• 1Y: 22.91%
• 3Y*: 15.92%
• 5Y*: 19.64%
• 10Y*: 4.02%

OCUL

• 1D: 5.73%
• 1M: 21.14%
• YTD: -17.87%
• 6M: -23.07%
• 1Y: 22.63%
• 3Y*: 26.98%
• 5Y*: -7.10%
• 10Y*: 6.79%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ANIP vs. OCUL - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
ANIP ANI Pharmaceuticals, Inc.	2.08%	42.80%	0.25%	37.06%	-12.70%	58.68%	-52.91%	36.98%	-30.15%	6.32%
OCUL Ocular Therapeutix, Inc.	-17.87%	42.15%	91.48%	58.72%	-59.68%	-66.33%	424.05%	-0.75%	-10.56%	-46.83%

Correlation

The correlation between ANIP and OCUL is 0.20, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.20
Correlation (3Y) Calculated over the trailing 3-year period	0.30
Correlation (5Y) Calculated over the trailing 5-year period	0.33
Correlation (10Y) Calculated over the trailing 10-year period	0.31
Correlation (All Time) Calculated using the full available price history since Jul 25, 2014	0.31

The correlation between ANIP and OCUL shifts across timeframes, from 0.20 (1 year) to 0.33 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ANIP : $1.74B OCUL : $2.23B
EPS ANIP : $4.26 OCUL : -$1.45
PS Ratio ANIP : 1.84 OCUL : 38.49
PB Ratio ANIP : 3.09 OCUL : 3.84
Total Revenue (TTM) ANIP : $923.71M OCUL : $52.04M
Gross Profit (TTM) ANIP : $486.11M OCUL : $45.40M
EBITDA (TTM) ANIP : $234.71M OCUL : -$283.03M

Return for Risk

ANIP vs. OCUL — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ANIP

ANIP Risk / Return Rank: 60
ANIP Sharpe Ratio Rank: 63
ANIP Sortino Ratio Rank: 63
ANIP Omega Ratio Rank: 59
ANIP Calmar Ratio Rank: 60
ANIP Martin Ratio Rank: 58

OCUL

OCUL Risk / Return Rank: 53
OCUL Sharpe Ratio Rank: 53
OCUL Sortino Ratio Rank: 57
OCUL Omega Ratio Rank: 55
OCUL Calmar Ratio Rank: 52
OCUL Martin Ratio Rank: 50

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ANIP vs. OCUL - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ANI Pharmaceuticals, Inc. (ANIP) and Ocular Therapeutix, Inc. (OCUL). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ANIP	OCUL	Difference
Sharpe ratio: Return per unit of total volatility	0.65	0.32	+0.32
Sortino ratio: Return per unit of downside risk	1.33	1.05	+0.28
Omega ratio: Gain probability vs. loss probability	1.15	1.13	+0.02
Calmar ratio: Return relative to maximum drawdown	0.80	0.40	+0.41
Martin ratio: Return relative to average drawdown	1.48	0.75	+0.73

ANIP vs. OCUL - Sharpe Ratio Comparison

The current ANIP Sharpe Ratio is 0.65, which is higher than the OCUL Sharpe Ratio of 0.32. The chart below compares the historical Sharpe Ratios of ANIP and OCUL, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ANIP vs. OCUL - Drawdown Comparison

The maximum ANIP drawdown since its inception was -98.81%, roughly equal to the maximum OCUL drawdown of -95.19%. Use the drawdown chart below to compare losses from any high point for ANIP and OCUL.

Drawdown Indicators

	ANIP	OCUL	Difference
Max Drawdown Largest peak-to-trough decline	-98.81%	-95.19%	-3.62%
Max Drawdown (1Y) Largest decline over 1 year	-28.66%	-57.29%	+28.63%
Max Drawdown (3Y) Largest decline over 3 years	-28.66%	-61.57%	+32.91%
Max Drawdown (5Y) Largest decline over 5 years	-59.38%	-85.78%	+26.40%
Max Drawdown (10Y) Largest decline over 10 years	-72.96%	-90.94%	+17.98%
Current Drawdown Current decline from peak	-82.09%	-76.96%	-5.13%
Average Drawdown Average peak-to-trough decline	-79.39%	-76.60%	-2.79%
Ulcer Index Depth and duration of drawdowns from previous peaks	15.54%	30.45%	-14.91%

Volatility

ANIP vs. OCUL - Volatility Comparison

The current volatility for ANI Pharmaceuticals, Inc. (ANIP) is 9.06%, while Ocular Therapeutix, Inc. (OCUL) has a volatility of 17.46%. This indicates that ANIP experiences smaller price fluctuations and is considered to be less risky than OCUL based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ANIP	OCUL	Difference
Volatility (1M) Calculated over the trailing 1-month period	9.06%	17.46%	-8.40%
Volatility (6M) Calculated over the trailing 6-month period	24.48%	54.60%	-30.12%
Volatility (1Y) Calculated over the trailing 1-year period	35.60%	70.19%	-34.59%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	46.33%	78.55%	-32.22%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	48.20%	78.85%	-30.65%

Dividends

ANIP vs. OCUL - Dividend Comparison

Neither ANIP nor OCUL has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ANIP and OCUL in my portfolio?

ANIP and OCUL have a correlation of 0.20, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ANIP or OCUL?

OCUL has higher volatility (17.46%) compared to ANIP (9.06%). In terms of maximum drawdown, ANIP dropped -98.81% vs OCUL's -95.19%.

Which has better risk-adjusted returns?

ANIP currently has the higher Sharpe Ratio (0.65 vs 0.32), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.