2B78.DE vs. XDWH.DE
2B78.DE (iShares Healthcare Innovation UCITS ETF) and XDWH.DE (Xtrackers MSCI World Health Care UCITS ETF 1C) are both Health & Biotech Equities funds - 2B78.DE tracks the iSTOXX® FactSet Breakthrough Healthcare while XDWH.DE tracks the MSCI World/Health Care NR USD. Both are passively managed. Over the past 5 years, 2B78.DE returned -1.74%/yr vs 5.50%/yr for XDWH.DE. A 0.74 correlation means they provide meaningful diversification when combined. 2B78.DE charges 0.40%/yr vs 0.25%/yr for XDWH.DE.
Performance
2B78.DE vs. XDWH.DE - Performance Comparison
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Returns By Period
The year-to-date returns for both investments are quite close, with 2B78.DE having a -2.07% return and XDWH.DE slightly higher at -1.98%.
2B78.DE
- 1D
- 0.41%
- 1M
- 1.41%
- YTD
- -2.07%
- 6M
- -3.15%
- 1Y
- 14.42%
- 3Y*
- 2.27%
- 5Y*
- -1.74%
- 10Y*
- —
XDWH.DE
- 1D
- 2.85%
- 1M
- 3.42%
- YTD
- -1.98%
- 6M
- -1.51%
- 1Y
- 9.79%
- 3Y*
- 2.67%
- 5Y*
- 5.50%
- 10Y*
- 7.61%
2B78.DE vs. XDWH.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
2B78.DE iShares Healthcare Innovation UCITS ETF | -2.07% | 5.50% | 7.24% | -0.29% | -19.03% | 1.15% | 38.75% | 16.74% | 0.39% | 19.45% |
XDWH.DE Xtrackers MSCI World Health Care UCITS ETF 1C | -1.98% | 2.21% | 7.44% | 0.04% | -0.07% | 30.55% | 2.69% | 27.24% | 5.96% | 5.52% |
Correlation
The correlation between 2B78.DE and XDWH.DE is 0.76, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.76 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.71 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.71 |
Correlation (All Time) Calculated using the full available price history since Sep 14, 2016 | 0.74 |
The correlation between 2B78.DE and XDWH.DE has been stable across timeframes, ranging from 0.71 to 0.76 - a consistent structural relationship.
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Return for Risk
2B78.DE vs. XDWH.DE — Risk / Return Rank
2B78.DE
XDWH.DE
2B78.DE vs. XDWH.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for iShares Healthcare Innovation UCITS ETF (2B78.DE) and Xtrackers MSCI World Health Care UCITS ETF 1C (XDWH.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| 2B78.DE | XDWH.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.26 | ||
| Sortino ratioReturn per unit of downside risk | +0.31 | ||
| Omega ratioGain probability vs. loss probability | 1.17 | 1.13 | +0.04 |
| Calmar ratioReturn relative to maximum drawdown | 1.24 | 0.93 | +0.31 |
| Martin ratioReturn relative to average drawdown | 3.07 | 2.28 | +0.79 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| 2B78.DE | XDWH.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.95 | 0.70 | +0.26 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.10 | 0.41 | -0.50 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.51 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | 0.31 | 0.55 | -0.24 |
Drawdowns
2B78.DE vs. XDWH.DE - Drawdown Comparison
The maximum 2B78.DE drawdown since its inception was -38.58%, which is greater than XDWH.DE's maximum drawdown of -26.08%. Use the drawdown chart below to compare losses from any high point for 2B78.DE and XDWH.DE.
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Drawdown Indicators
| 2B78.DE | XDWH.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -38.58% | -26.08% | -12.50% |
Max Drawdown (1Y)Largest decline over 1 year | -12.05% | -10.32% | -1.73% |
Max Drawdown (3Y)Largest decline over 3 years | -25.32% | -21.12% | -4.20% |
Max Drawdown (5Y)Largest decline over 5 years | -36.99% | -21.12% | -15.87% |
Max Drawdown (10Y)Largest decline over 10 years | — | -26.08% | — |
Current DrawdownCurrent decline from peak | -19.03% | -8.51% | -10.52% |
Average DrawdownAverage peak-to-trough decline | -14.36% | -4.82% | -9.54% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 4.86% | 4.20% | +0.66% |
Volatility
2B78.DE vs. XDWH.DE - Volatility Comparison
The current volatility for iShares Healthcare Innovation UCITS ETF (2B78.DE) is 3.74%, while Xtrackers MSCI World Health Care UCITS ETF 1C (XDWH.DE) has a volatility of 4.81%. This indicates that 2B78.DE experiences smaller price fluctuations and is considered to be less risky than XDWH.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| 2B78.DE | XDWH.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 3.74% | 4.81% | -1.07% |
Volatility (6M)Calculated over the trailing 6-month period | 10.97% | 9.51% | +1.46% |
Volatility (1Y)Calculated over the trailing 1-year period | 15.67% | 13.69% | +1.98% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 17.91% | 13.43% | +4.48% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.79% | 14.69% | +4.10% |
2B78.DE vs. XDWH.DE - Expense Ratio Comparison
2B78.DE has a 0.40% expense ratio, which is higher than XDWH.DE's 0.25% expense ratio.
Dividends
2B78.DE vs. XDWH.DE - Dividend Comparison
Neither 2B78.DE nor XDWH.DE has paid dividends to shareholders.
Frequently Asked Questions
2B78.DE and XDWH.DE have a correlation of 0.76, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, XDWH.DE is cheaper at 0.25% per year. The better choice depends on whether you care most about return, fees, risk, or income.
XDWH.DE is cheaper with a 0.25% expense ratio, compared with 0.40% for 2B78.DE.
2B78.DE tracks iSTOXX® FactSet Breakthrough Healthcare, while XDWH.DE tracks MSCI World/Health Care NR USD. They also come from different issuers: iShares and Xtrackers. Their fees differ too: 0.40% for 2B78.DE and 0.25% for XDWH.DE.
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