- ISIN
- US68375N1037
- CUSIP
- 68375N103
- Sector
- Healthcare
- Industry
- Diagnostics & Research
- IPO Date
- Nov 2, 1995
Highlights
- Market Cap
- $1.09B
- Enterprise Value
- $907.79M
- EPS (TTM)
- -$0.29
- Total Revenue (TTM)
- $581.17M
- Gross Profit (TTM)
- $277.22M
- EBITDA (TTM)
- -$65.07M
- Year Range
- $0.98 - $1.60
- Target Price
- $1.60
- ROA (TTM)
- -11.47%
- ROE (TTM)
- -17.68%
Share Price Chart
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Performance
OPK Performance Chart
OPKO Health, Inc. (OPK) is up 13.5% since the beginning of the year. At $1 per share, OPK is trading 10.6% below its 52-week high of $2. Investors who bought $1,000 worth of OPK shares 5 years ago would now be looking at an investment worth $387.
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Returns By Period
OPKO Health, Inc. (OPK) has returned 13.49% so far this year and 10.85% over the past 12 months. Over the last ten years, OPK has returned -17.22% per year, falling short of the S&P 500 Index benchmark, which averaged 13.88% annually.
OPKO Health, Inc.
- 1D
- 0.70%
- 1M
- 12.60%
- YTD
- 13.49%
- 6M
- 7.52%
- 1Y
- 10.85%
- 3Y*
- -3.68%
- 5Y*
- -17.31%
- 10Y*
- -17.22%
Benchmark (S&P 500 Index)
- 1D
- -0.37%
- 1M
- -0.01%
- YTD
- 9.16%
- 6M
- 8.64%
- 1Y
- 25.22%
- 3Y*
- 19.78%
- 5Y*
- 11.99%
- 10Y*
- 13.88%
OPK Monthly Returns History
Based on dividend-adjusted daily data since Nov 2, 1995, OPK's average daily return is +0.11%, while the average monthly return is +1.72%. At this rate, an investment would double in approximately 3.4 years.
Historically, 47% of months were positive and 53% were negative. The best month was Aug 2006 with a return of +156.4%, while the worst month was Aug 1998 at -43.4%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 8 months.
On a daily basis, OPK closed higher 42% of trading days. The best single day was Apr 24, 2003 with a return of +64.3%, while the worst single day was Jan 4, 2024 at -39.6%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 0.00% | -4.76% | -5.00% | -1.32% | 29.78% | -2.05% | 13.49% | ||||||
| 2025 | 3.40% | 14.47% | -4.60% | -16.87% | -1.45% | -2.94% | -3.03% | 7.81% | 12.32% | -12.26% | 0.00% | -7.35% | -14.29% |
| 2024 | -32.45% | -1.96% | 20.00% | 1.67% | 12.30% | -8.76% | 13.60% | 18.31% | -11.31% | 1.34% | 1.99% | -4.55% | -2.65% |
| 2023 | 3.20% | -11.63% | 28.07% | 0.68% | -5.44% | 56.12% | -14.29% | -1.61% | -12.57% | -21.88% | 16.80% | 3.42% | 20.80% |
| 2022 | -34.93% | 0.00% | 9.90% | -21.51% | 11.11% | -15.67% | -6.72% | -7.63% | -13.30% | 0.53% | -21.05% | -16.67% | -74.01% |
| 2021 | 36.96% | -16.82% | -4.67% | -4.43% | -6.83% | 6.02% | -15.06% | 12.21% | -5.44% | 3.84% | 3.69% | 22.39% | 21.77% |
Benchmark Metrics
OPKO Health, Inc. has an annualized alpha of 19.67%, beta of 1.04, and R2 of 0.06 versus S&P 500 Index. Calculated based on daily prices since November 02, 1995.
- This stock participated in 137.33% of S&P 500 Index downside but only 85.87% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.06 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- 19.67%
- Beta
- 1.04
- R²
- 0.06
- Upside Capture
- 85.87%
- Downside Capture
- 137.33%
Return for Risk
Risk / Return Rank
OPK ranks 50 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for OPKO Health, Inc. (OPK) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| OPK | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.74 | ||
| Sortino ratioReturn per unit of downside risk | -2.05 | ||
| Omega ratioGain probability vs. loss probability | 1.08 | 1.37 | -0.28 |
| Calmar ratioReturn relative to maximum drawdown | 0.36 | 2.78 | -2.43 |
| Martin ratioReturn relative to average drawdown | 0.64 | 12.44 | -11.80 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the OPKO Health, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the OPKO Health, Inc. was 98.17%, occurring on Jan 3, 2005. Recovery took 2612 trading sessions.
The current OPKO Health, Inc. drawdown is 92.52%.
Related event | Drawdown | Fall | Recovery | Underwater |
|---|---|---|---|---|
2005 bear market2005 | -98.17%Jan 2005 | 4y 10mo | 10y 4mo | 15y 3moFeb 2000 - May 2015 |
2024 bear market2024 | -95.47%Mar 2024 | 8y 9mo | — | 11y 22dJun 2015 - now |
1998 bear market1998 | -77.59%Sep 1998 | 3mo | 1y 4mo | 1y 7moJun 1998 - Jan 2000 |
1996 bear market1996 | -66.67%Dec 1996 | 6mo 26d | 8mo 22d | 1y 3moJun 1996 - Sep 1997 |
1998 bear market1998 | -42.36%Jan 1998 | 3mo 1d | 2mo 9d | 5mo 10dOct 1997 - Mar 1998 |
Drawdown Indicators
| OPK | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.17% | -56.78% | -41.39% |
Max Drawdown (1Y)Largest decline over 1 year | -30.38% | -9.10% | -21.28% |
Max Drawdown (3Y)Largest decline over 3 years | -60.12% | -18.90% | -41.22% |
Max Drawdown (5Y)Largest decline over 5 years | -83.19% | -25.43% | -57.76% |
Max Drawdown (10Y)Largest decline over 10 years | -92.73% | -33.92% | -58.81% |
Current DrawdownCurrent decline from peak | -92.52% | -1.80% | -90.72% |
Average DrawdownAverage peak-to-trough decline | -73.12% | -10.71% | -62.41% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 16.91% | 2.03% | +14.88% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of OPKO Health, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how OPKO Health, Inc. is priced in the market compared to other companies in the Diagnostics & Research industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for OPK relative to other companies in the Diagnostics & Research industry. Currently, OPK has a P/S ratio of 1.8. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for OPK in comparison with other companies in the Diagnostics & Research industry. Currently, OPK has a P/B value of 0.9. This P/B ratio is low compared to industry peers. It might indicate the stock is undervalued or that the company’s assets are not expected to generate strong returns.
Income Statement
| TTM | |
|---|---|
Revenue | — |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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