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OPKO Health, Inc. (OPK)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
US68375N1037
CUSIP
68375N103
IPO Date
Nov 2, 1995

Highlights

Market Cap
$872.69M
Enterprise Value
$937.02M
EPS (TTM)
-$0.31
Total Revenue (TTM)
$606.93M
Gross Profit (TTM)
$251.79M
EBITDA (TTM)
-$66.36M
Year Range
$1.10 - $1.64
Target Price
$1.60
ROA (TTM)
-11.68%
ROE (TTM)
-17.80%

Share Price Chart


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OPKO Health, Inc.

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in OPKO Health, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

OPKO Health, Inc. (OPK) has returned -9.52% so far this year and -31.33% over the past 12 months. Over the last ten years, OPK has returned -19.84% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.


OPKO Health, Inc.

1D
3.64%
1M
-5.00%
YTD
-9.52%
6M
-26.45%
1Y
-31.33%
3Y*
-7.92%
5Y*
-23.60%
10Y*
-19.84%

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Nov 2, 1995, OPK's average daily return is +0.11%, while the average monthly return is +1.67%. At this rate, your investment would double in approximately 3.5 years.

Historically, 47% of months were positive and 53% were negative. The best month was Aug 2006 with a return of +156.4%, while the worst month was Aug 1998 at -43.4%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 8 months.

On a daily basis, OPK closed higher 42% of trading days. The best single day was Apr 24, 2003 with a return of +64.3%, while the worst single day was Jan 4, 2024 at -39.6%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-0.00%-4.76%-5.00%-9.52%
20253.40%14.47%-4.60%-16.87%-1.45%-2.94%-3.03%7.81%12.32%-12.26%-0.00%-7.35%-14.29%
2024-32.45%-1.96%20.00%1.67%12.30%-8.76%13.60%18.31%-11.31%1.34%1.99%-4.55%-2.65%
20233.20%-11.63%28.07%0.68%-5.44%56.12%-14.29%-1.61%-12.57%-21.88%16.80%3.42%20.80%
2022-34.93%0.00%9.90%-21.51%11.11%-15.67%-6.72%-7.63%-13.30%0.53%-21.05%-16.67%-74.01%
202136.96%-16.82%-4.67%-4.43%-6.83%6.02%-15.06%12.21%-5.44%3.84%3.69%22.39%21.77%

Benchmark Metrics

OPKO Health, Inc. has an annualized alpha of 19.44%, beta of 1.04, and R² of 0.06 versus S&P 500 Index. Calculated based on daily prices since November 03, 1995.

  • This stock participated in 137.28% of S&P 500 Index downside but only 84.26% of its upside — more exposed to losses than it benefited from rallies.
  • R² of 0.06 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
19.44%
Beta
1.04
0.06
Upside Capture
84.26%
Downside Capture
137.28%

Return for Risk

Risk / Return Rank

OPK ranks 7 for risk / return — in the bottom 7% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.


OPK Risk / Return Rank: 77
Overall Rank
OPK Sharpe Ratio Rank: 77
Sharpe Ratio Rank
OPK Sortino Ratio Rank: 99
Sortino Ratio Rank
OPK Omega Ratio Rank: 1111
Omega Ratio Rank
OPK Calmar Ratio Rank: 33
Calmar Ratio Rank
OPK Martin Ratio Rank: 66
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for OPKO Health, Inc. (OPK) and compare them to a chosen benchmark (S&P 500 Index).


OPKBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

-0.83

0.90

-1.73

Sortino ratio

Return per unit of downside risk

-1.13

1.39

-2.51

Omega ratio

Gain probability vs. loss probability

0.87

1.21

-0.34

Calmar ratio

Return relative to maximum drawdown

-0.98

1.40

-2.38

Martin ratio

Return relative to average drawdown

-1.64

6.61

-8.25

Explore OPK risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


OPKO Health, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the OPKO Health, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the OPKO Health, Inc. was 98.17%, occurring on Jan 3, 2005. Recovery took 2612 trading sessions.

The current OPKO Health, Inc. drawdown is 94.04%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-98.17%Feb 22, 20001223Jan 3, 20052612May 20, 20153835
-95.47%Jun 4, 20152212Mar 18, 2024
-77.59%Jun 3, 199864Sep 1, 1998355Jan 28, 2000419
-66.67%Jun 7, 1996143Dec 30, 1996182Sep 18, 1997325
-42.36%Oct 21, 199762Jan 20, 199848Mar 30, 1998110

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of OPKO Health, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how OPKO Health, Inc. is priced in the market compared to other companies in the Diagnostics & Research industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for OPK relative to other companies in the Diagnostics & Research industry. Currently, OPK has a P/S ratio of 1.4. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for OPK in comparison with other companies in the Diagnostics & Research industry. Currently, OPK has a P/B value of 0.7. This P/B ratio is low compared to industry peers. It might indicate the stock is undervalued or that the company’s assets are not expected to generate strong returns.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items