OPK vs. SMCI
OPK (OPKO Health, Inc.) and SMCI (Super Micro Computer, Inc.) are both stocks. OPK operates in Diagnostics & Research (Healthcare), while SMCI operates in Computer Hardware (Technology). Over the past 10 years, OPK returned -17.51%/yr vs 33.40%/yr for SMCI. At a 0.25 correlation, their price movements are largely independent.
Performance
OPK vs. SMCI - Performance Comparison
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Returns By Period
In the year-to-date period, OPK achieves a 15.87% return, which is significantly lower than SMCI's 62.01% return. Over the past 10 years, OPK has underperformed SMCI with an annualized return of -17.51%, while SMCI has yielded a comparatively higher 33.40% annualized return.
OPK
- 1D
- 4.29%
- 1M
- 31.53%
- YTD
- 15.87%
- 6M
- 6.57%
- 1Y
- 5.80%
- 3Y*
- 0.23%
- 5Y*
- -16.56%
- 10Y*
- -17.51%
SMCI
- 1D
- -5.48%
- 1M
- 69.84%
- YTD
- 62.01%
- 6M
- 40.80%
- 1Y
- 9.79%
- 3Y*
- 28.80%
- 5Y*
- 66.83%
- 10Y*
- 33.40%
OPK vs. SMCI - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
OPK OPKO Health, Inc. | 15.87% | -14.29% | -2.65% | 20.80% | -74.01% | 21.77% | 168.71% | -51.16% | -38.57% | -47.31% |
SMCI Super Micro Computer, Inc. | 62.01% | -3.97% | 7.23% | 246.24% | 86.80% | 38.82% | 31.81% | 74.06% | -34.07% | -25.38% |
Correlation
The correlation between OPK and SMCI is 0.21, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.21 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.22 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.24 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.22 |
Correlation (All Time) Calculated using the full available price history since Mar 30, 2007 | 0.25 |
Fundamentals
OPK:
$1.11B
SMCI:
$31.94B
OPK:
-$0.29
SMCI:
$2.70
OPK:
1.87
SMCI:
0.93
OPK:
0.92
SMCI:
4.22
OPK:
$581.17M
SMCI:
$33.70B
OPK:
$277.22M
SMCI:
$2.83B
OPK:
-$65.07M
SMCI:
$1.47B
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Return for Risk
OPK vs. SMCI — Risk / Return Rank
OPK
SMCI
OPK vs. SMCI - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for OPKO Health, Inc. (OPK) and Super Micro Computer, Inc. (SMCI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| OPK | SMCI | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.03 | ||
| Sortino ratioReturn per unit of downside risk | -0.24 | ||
| Omega ratioGain probability vs. loss probability | 1.06 | 1.10 | -0.04 |
| Calmar ratioReturn relative to maximum drawdown | 0.19 | 0.15 | +0.04 |
| Martin ratioReturn relative to average drawdown | 0.35 | 0.25 | +0.09 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| OPK | SMCI | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 0.15 | 0.12 | +0.03 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.29 | 0.79 | -1.08 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.27 | 0.48 | -0.75 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.04 | 0.37 | -0.42 |
Drawdowns
OPK vs. SMCI - Drawdown Comparison
The maximum OPK drawdown since its inception was -98.17%, which is greater than SMCI's maximum drawdown of -84.84%. Use the drawdown chart below to compare losses from any high point for OPK and SMCI.
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Drawdown Indicators
| OPK | SMCI | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -98.17% | -84.84% | -13.33% |
Max Drawdown (1Y)Largest decline over 1 year | -30.38% | -66.18% | +35.80% |
Max Drawdown (3Y)Largest decline over 3 years | -60.12% | -84.84% | +24.72% |
Max Drawdown (5Y)Largest decline over 5 years | -83.19% | -84.84% | +1.65% |
Max Drawdown (10Y)Largest decline over 10 years | -92.73% | -84.84% | -7.89% |
Current DrawdownCurrent decline from peak | -92.36% | -60.09% | -32.27% |
Average DrawdownAverage peak-to-trough decline | -73.10% | -31.94% | -41.16% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 16.83% | 38.80% | -21.97% |
Volatility
OPK vs. SMCI - Volatility Comparison
The current volatility for OPKO Health, Inc. (OPK) is 13.93%, while Super Micro Computer, Inc. (SMCI) has a volatility of 30.41%. This indicates that OPK experiences smaller price fluctuations and is considered to be less risky than SMCI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| OPK | SMCI | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 13.93% | 30.41% | -16.48% |
Volatility (6M)Calculated over the trailing 6-month period | 26.91% | 66.39% | -39.48% |
Volatility (1Y)Calculated over the trailing 1-year period | 37.75% | 79.02% | -41.27% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 56.45% | 85.25% | -28.80% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 64.77% | 70.43% | -5.66% |
Dividends
OPK vs. SMCI - Dividend Comparison
Neither OPK nor SMCI has paid dividends to shareholders.
Financials
OPK vs. SMCI - Financials Comparison
This section allows you to compare key financial metrics between OPKO Health, Inc. and Super Micro Computer, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
OPK vs. SMCI - Profitability Comparison
OPK - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, OPKO Health, Inc. reported a gross profit of 68.05M and revenue of 124.20M. Therefore, the gross margin over that period was 54.8%.
SMCI - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Super Micro Computer, Inc. reported a gross profit of 1.02B and revenue of 10.24B. Therefore, the gross margin over that period was 10.0%.
OPK - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, OPKO Health, Inc. reported an operating income of -51.02M and revenue of 124.20M, resulting in an operating margin of -41.1%.
SMCI - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Super Micro Computer, Inc. reported an operating income of 625.87M and revenue of 10.24B, resulting in an operating margin of 6.1%.
OPK - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, OPKO Health, Inc. reported a net income of -54.85M and revenue of 124.20M, resulting in a net margin of -44.2%.
SMCI - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Super Micro Computer, Inc. reported a net income of 1.02B and revenue of 10.24B, resulting in a net margin of 9.9%.
Frequently Asked Questions
OPK and SMCI have a correlation of 0.21, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SMCI has higher volatility (30.41%) compared to OPK (13.93%). In terms of maximum drawdown, OPK dropped -98.17% vs SMCI's -84.84%.
OPK currently has the higher Sharpe Ratio (0.15 vs 0.12), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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