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ISIN
US4497781090
CUSIP
449778109
IPO Date
Nov 5, 2021

Highlights

Market Cap
$3.21M
Enterprise Value
-$25.21M
EPS (TTM)
-$1.33
Gross Profit (TTM)
-$910.00K
EBITDA (TTM)
-$87.26M
Year Range
$0.03 - $2.79
ROA (TTM)
-221.12%
ROE (TTM)
-9,698.02%

Share Price Chart


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IO Biotech, Inc.

Often compared with IOBT:
IOBT vs. PSTVIOBT vs. NVTS

Performance

IOBT Performance Chart


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S&P 500 Index

Returns By Period


IO Biotech, Inc.

1D
1M
YTD
6M
1Y
3Y*
5Y*
10Y*

Benchmark (S&P 500 Index)

1D
-0.74%
1M
4.90%
YTD
10.35%
6M
10.28%
1Y
26.52%
3Y*
20.83%
5Y*
12.30%
10Y*
13.66%
*Multi-year figures are annualized to reflect compound growth (CAGR)

IOBT Monthly Returns History


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-52.36%20.30%-83.18%-18.23%-92.12%
2025-2.17%5.00%15.34%-11.01%46.39%-2.11%60.43%-29.15%-77.02%186.42%-30.81%-15.38%-33.82%
2024-7.45%-8.05%8.13%-15.61%-19.18%-0.85%15.38%11.11%-30.00%18.10%-28.23%3.37%-51.06%
202320.43%-8.30%-26.18%1.87%8.90%-6.01%-5.88%-0.00%-23.37%-39.23%36.54%60.68%-18.26%
202233.59%-16.02%-26.18%36.79%-33.38%-3.31%-17.13%-14.21%-18.37%-8.86%17.81%-20.96%-64.06%
2021-40.38%-31.40%-59.11%

Benchmark Metrics

IO Biotech, Inc. has an annualized alpha of -31.12%, beta of 0.75, and R2 of 0.01 versus S&P 500 Index. Calculated based on daily prices since November 08, 2021.

  • This stock participated in 222.22% of S&P 500 Index downside but only -113.62% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.01 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
-31.12%
Beta
0.75
0.01
Upside Capture
-113.62%
Downside Capture
222.22%

Return for Risk

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for IO Biotech, Inc. (IOBT) and compare them to S&P 500 Index.


Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Dividends

Dividend History


IO Biotech, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the IO Biotech, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the IO Biotech, Inc. was 99.79%, occurring on Apr 2, 2026. The portfolio has not yet recovered.


Related event

Drawdown

Fall

Recovery

Underwater

2026 bear market2026
-99.79%Apr 2026
4y 4mo
4y 6moNov 2021 - now

Drawdown Indicators


IOBTBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-56.78%

Max Drawdown (1Y)

Largest decline over 1 year

-9.10%

Max Drawdown (3Y)

Largest decline over 3 years

-18.90%

Max Drawdown (5Y)

Largest decline over 5 years

-25.43%

Max Drawdown (10Y)

Largest decline over 10 years

-33.92%

Current Drawdown

Current decline from peak

-0.74%

Average Drawdown

Average peak-to-trough decline

-10.72%

Ulcer Index

Depth and duration of drawdowns from previous peaks

1.97%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of IO Biotech, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how IO Biotech, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for IOBT in comparison with other companies in the Biotechnology industry. Currently, IOBT has a P/B value of 3.5. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
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