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ISIN
US22663K1079
CUSIP
22663K107
IPO Date
Jul 18, 2018

Highlights

Market Cap
$3.68B
Enterprise Value
$3.62B
EPS (TTM)
-$5.14
Total Revenue (TTM)
$15.79M
Gross Profit (TTM)
$16.05M
EBITDA (TTM)
-$531.75M
Year Range
$25.83 - $57.99
Target Price
$86.60
ROA (TTM)
-35.42%
ROE (TTM)
-38.76%

Share Price Chart


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Crinetics Pharmaceuticals, Inc.

Performance

CRNX Performance Chart

Crinetics Pharmaceuticals, Inc. (CRNX) is down 24.0% since the beginning of the year. At $35 per share, CRNX is trading 39.0% below its 52-week high of $58. Investors who bought $1,000 worth of CRNX shares 5 years ago would now be looking at an investment worth $1,743.


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S&P 500 Index

Returns By Period

Crinetics Pharmaceuticals, Inc. (CRNX) has returned -24.00% so far this year and 17.31% over the past 12 months.


Crinetics Pharmaceuticals, Inc.

1D
-1.37%
1M
-3.86%
YTD
-24.00%
6M
-28.15%
1Y
17.31%
3Y*
24.10%
5Y*
11.75%
10Y*

Benchmark (S&P 500 Index)

1D
-0.37%
1M
-0.01%
YTD
9.16%
6M
8.64%
1Y
25.22%
3Y*
19.78%
5Y*
11.99%
10Y*
13.88%
*Multi-year figures are annualized to reflect compound growth (CAGR)

CRNX Monthly Returns History

Based on dividend-adjusted daily data since Jul 18, 2018, CRNX's average daily return is +0.11%, while the average monthly return is +1.71%. At this rate, an investment would double in approximately 3.4 years.

Historically, 53% of months were positive and 47% were negative. The best month was Sep 2023 with a return of +71.7%, while the worst month was Jan 2022 at -33.5%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 8 months.

On a daily basis, CRNX closed higher 49% of trading days. The best single day was Sep 11, 2023 with a return of +63.3%, while the worst single day was Jun 22, 2020 at -17.1%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
20267.28%-17.70%-11.63%6.77%-8.33%-0.48%-24.00%
2025-21.18%-11.22%-6.26%-0.45%-8.63%-5.74%-0.59%8.39%34.40%4.44%4.74%2.17%-8.96%
20242.53%12.23%14.34%-6.39%1.35%0.86%18.60%-0.11%-3.69%9.51%2.22%-10.61%43.70%
20237.16%0.15%-18.23%21.67%11.72%-17.45%5.44%-8.84%71.71%-1.51%8.54%11.92%94.43%
2022-33.51%5.98%9.64%-7.43%-17.57%11.34%3.00%-1.72%4.03%-6.01%-3.20%2.41%-35.59%
20211.70%6.55%-0.07%13.29%1.39%7.41%-4.62%31.09%-10.69%18.43%9.59%3.99%101.35%

Benchmark Metrics

Crinetics Pharmaceuticals, Inc. has an annualized alpha of 12.51%, beta of 1.15, and R2 of 0.12 versus S&P 500 Index. Calculated based on daily prices since July 18, 2018.

  • This stock participated in 116.61% of S&P 500 Index downside but only 98.04% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.12 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
12.51%
Beta
1.15
0.12
Upside Capture
98.04%
Downside Capture
116.61%

Return for Risk

Risk / Return Rank

CRNX ranks 53 for risk / return — on par with similar stocks. You're getting a typical balance of risk and reward. Not a standout, but not a red flag either — a reasonable choice if other factors align with your goals.


CRNX Risk / Return Rank: 5353
Overall Rank
CRNX Sharpe Ratio Rank: 5353
Sharpe Ratio Rank
CRNX Sortino Ratio Rank: 5454
Sortino Ratio Rank
CRNX Omega Ratio Rank: 5151
Omega Ratio Rank
CRNX Calmar Ratio Rank: 5252
Calmar Ratio Rank
CRNX Martin Ratio Rank: 5252
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Crinetics Pharmaceuticals, Inc. (CRNX) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


CRNXBenchmarkDifference
Sharpe ratioReturn per unit of total volatility

-1.73

Sortino ratioReturn per unit of downside risk

-1.83

Omega ratioGain probability vs. loss probability

1.11

1.37

-0.26

Calmar ratioReturn relative to maximum drawdown

0.41

2.78

-2.37

Martin ratioReturn relative to average drawdown

0.84

12.44

-11.60

Dividends

Dividend History


Crinetics Pharmaceuticals, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Crinetics Pharmaceuticals, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Crinetics Pharmaceuticals, Inc. was 68.70%, occurring on Mar 16, 2020. Recovery took 948 trading sessions.

The current Crinetics Pharmaceuticals, Inc. drawdown is 41.70%.


Related event

Drawdown

Fall

Recovery

Underwater

COVID crash2020
-68.70%Mar 2020
1y 6mo3y 9mo
5y 3moSep 2018 - Dec 2023
2025 selloff2025
-57.88%Apr 2025
4mo 28d
1y 7moNov 2024 - now
2024 correction2024
-18.72%Jun 2024
1mo 10d15d
1mo 25dMay 2024 - Jul 2024
2024 correction2024
-17.60%Mar 2024
14d10d
24dMar 2024 - Mar 2024
2024 correction2024
-13.35%Aug 2024
23d2mo 7d
3moJul 2024 - Oct 2024

Drawdown Indicators


CRNXBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-68.70%

-56.78%

-11.92%

Max Drawdown (1Y)

Largest decline over 1 year

-42.21%

-9.10%

-33.11%

Max Drawdown (3Y)

Largest decline over 3 years

-57.88%

-18.90%

-38.98%

Max Drawdown (5Y)

Largest decline over 5 years

-57.88%

-25.43%

-32.45%

Max Drawdown (10Y)

Largest decline over 10 years

-33.92%

Current Drawdown

Current decline from peak

-41.70%

-1.80%

-39.90%

Average Drawdown

Average peak-to-trough decline

-37.33%

-10.71%

-26.62%

Ulcer Index

Depth and duration of drawdowns from previous peaks

20.69%

2.03%

+18.66%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Crinetics Pharmaceuticals, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Crinetics Pharmaceuticals, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for CRNX relative to other companies in the Biotechnology industry. Currently, CRNX has a P/S ratio of 216.3. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for CRNX in comparison with other companies in the Biotechnology industry. Currently, CRNX has a P/B value of 2.9. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
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