ZVRA vs. ISSC
ZVRA (Zevra Therapeutics Inc.) and ISSC (Innovative Solutions and Support, Inc.) are both stocks. ZVRA operates in Biotechnology (Healthcare), while ISSC operates in Aerospace & Defense (Industrials). Over the past 10 years, ZVRA returned -16.40%/yr vs 21.80%/yr for ISSC. At a 0.09 correlation, their price movements are largely independent.
Performance
ZVRA vs. ISSC - Performance Comparison
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Returns By Period
In the year-to-date period, ZVRA achieves a 41.18% return, which is significantly higher than ISSC's -2.43% return. Over the past 10 years, ZVRA has underperformed ISSC with an annualized return of -16.40%, while ISSC has yielded a comparatively higher 21.80% annualized return.
ZVRA
- 1D
- -2.47%
- 1M
- 13.76%
- YTD
- 41.18%
- 6M
- 51.86%
- 1Y
- 35.01%
- 3Y*
- 29.54%
- 5Y*
- -2.85%
- 10Y*
- -16.40%
ISSC
- 1D
- -4.59%
- 1M
- -10.25%
- YTD
- -2.43%
- 6M
- 65.59%
- 1Y
- 50.12%
- 3Y*
- 38.47%
- 5Y*
- 24.62%
- 10Y*
- 21.80%
ZVRA vs. ISSC - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
ZVRA Zevra Therapeutics Inc. | 41.18% | 7.43% | 27.33% | 42.70% | -47.30% | -22.23% | 84.70% | -78.71% | -56.05% | 37.29% |
ISSC Innovative Solutions and Support, Inc. | -2.43% | 121.78% | 0.12% | 3.77% | 25.32% | 0.61% | 29.83% | 158.41% | -23.13% | -11.71% |
Correlation
The correlation between ZVRA and ISSC is 0.21, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.21 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.16 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.13 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.09 |
Correlation (All Time) Calculated using the full available price history since Apr 16, 2015 | 0.09 |
The correlation between ZVRA and ISSC shifts across timeframes, from 0.09 (all time) to 0.21 (1 year), reflecting how their relationship changes across market environments.
Fundamentals
ZVRA:
$761.92M
ISSC:
$338.23M
ZVRA:
$2.16
ISSC:
$0.94
ZVRA:
5.85
ISSC:
19.62
ZVRA:
5.94
ISSC:
3.69
ZVRA:
3.70
ISSC:
4.69
ZVRA:
$122.29M
ISSC:
$90.56M
ZVRA:
$104.94M
ISSC:
$44.22M
ZVRA:
$149.15M
ISSC:
$26.70M
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Return for Risk
ZVRA vs. ISSC — Risk / Return Rank
ZVRA
ISSC
ZVRA vs. ISSC - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Zevra Therapeutics Inc. (ZVRA) and Innovative Solutions and Support, Inc. (ISSC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| ZVRA | ISSC | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.05 | ||
| Sortino ratioReturn per unit of downside risk | -0.11 | ||
| Omega ratioGain probability vs. loss probability | 1.16 | 1.18 | -0.02 |
| Calmar ratioReturn relative to maximum drawdown | 0.81 | 0.87 | -0.06 |
| Martin ratioReturn relative to average drawdown | 1.41 | 1.59 | -0.18 |
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Drawdowns
ZVRA vs. ISSC - Drawdown Comparison
The maximum ZVRA drawdown since its inception was -99.27%, which is greater than ISSC's maximum drawdown of -89.03%. Use the drawdown chart below to compare losses from any high point for ZVRA and ISSC.
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Drawdown Indicators
| ZVRA | ISSC | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.27% | -89.03% | -10.24% |
Max Drawdown (1Y)Largest decline over 1 year | -43.47% | -57.83% | +14.36% |
Max Drawdown (3Y)Largest decline over 3 years | -43.47% | -57.83% | +14.36% |
Max Drawdown (5Y)Largest decline over 5 years | -74.01% | -57.83% | -16.18% |
Max Drawdown (10Y)Largest decline over 10 years | -97.85% | -62.41% | -35.44% |
Current DrawdownCurrent decline from peak | -96.65% | -39.53% | -57.12% |
Average DrawdownAverage peak-to-trough decline | -86.41% | -50.58% | -35.83% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 24.87% | 31.63% | -6.76% |
Volatility
ZVRA vs. ISSC - Volatility Comparison
The current volatility for Zevra Therapeutics Inc. (ZVRA) is 24.56%, while Innovative Solutions and Support, Inc. (ISSC) has a volatility of 25.92%. This indicates that ZVRA experiences smaller price fluctuations and is considered to be less risky than ISSC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| ZVRA | ISSC | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 24.56% | 25.92% | -1.36% |
Volatility (6M)Calculated over the trailing 6-month period | 40.23% | 65.82% | -25.59% |
Volatility (1Y)Calculated over the trailing 1-year period | 62.90% | 83.28% | -20.38% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 60.49% | 59.11% | +1.38% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 81.46% | 57.12% | +24.34% |
Dividends
ZVRA vs. ISSC - Dividend Comparison
Neither ZVRA nor ISSC has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
ISSC Innovative Solutions and Support, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.01% | 0.00% | 17.64% |
ZVRA Zevra Therapeutics Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
ZVRA vs. ISSC - Financials Comparison
This section allows you to compare key financial metrics between Zevra Therapeutics Inc. and Innovative Solutions and Support, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
ZVRA and ISSC have a correlation of 0.21, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ISSC has higher volatility (25.92%) compared to ZVRA (24.56%). In terms of maximum drawdown, ZVRA dropped -99.27% vs ISSC's -89.03%.
ISSC currently has the higher Sharpe Ratio (0.60 vs 0.56), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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