ZVRA vs. GLBE

Last updated Aug 1, 2026

ZVRA (Zevra Therapeutics Inc.) and GLBE (Global-e Online Ltd.) are both stocks. ZVRA operates in Biotechnology (Healthcare), while GLBE operates in Internet Retail (Consumer Cyclical). Over the past 5 years, ZVRA returned -1.18%/yr vs -10.81%/yr for GLBE. Their 0.28 correlation means their historical movements had little consistent relationship.

Performance

ZVRA vs. GLBE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Zevra Therapeutics Inc. (ZVRA) and Global-e Online Ltd. (GLBE). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

ZVRA

• 1D: -1.35%
• 1M: -31.14%
• 6M: 5.67%
• YTD: 6.14%
• 1Y: -14.40%
• 3Y*: 24.74%
• 5Y*: -1.18%
• 10Y*: -17.62%
• ALL TIME*: -23.23%

GLBE

• 1D: -1.40%
• 1M: 9.71%
• 6M: 7.55%
• YTD: 0.00%
• 1Y: 18.58%
• 3Y*: -4.37%
• 5Y*: -10.81%
• 10Y*: —
• ALL TIME*: 9.70%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
GLBE Global-e Online Ltd.	$66.86M	$52.38M	$58.11M
ZVRA Zevra Therapeutics Inc.	$18.33M	$18.68M	$21.76M

ZVRA vs. GLBE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
ZVRA Zevra Therapeutics Inc.	6.14%	7.43%	27.33%	42.70%	-47.30%	-0.23%
GLBE Global-e Online Ltd.	-0.00%	-27.91%	37.60%	92.01%	-67.44%	161.40%

Correlation

The correlation between ZVRA and GLBE is 0.11, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.11
Correlation (3Y) Balances recent behavior with more history.	0.19
Correlation (5Y) Shows whether the relationship held over a longer period.	0.28
Correlation (All Time) Calculated using the full available price history since May 12, 2021	0.28

The correlation between ZVRA and GLBE shifts across timeframes, from 0.11 (1 year) to 0.28 (5 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap ZVRA : $562.18M GLBE : $6.60B
EPS ZVRA : $2.15 GLBE : $0.66
PE Ratio ZVRA : 4.43 GLBE : 59.18
PS Ratio ZVRA : 4.50 GLBE : 6.73
PB Ratio ZVRA : 2.78 GLBE : 7.51
Total Revenue (TTM) ZVRA : $122.29M GLBE : $1.02B
Gross Profit (TTM) ZVRA : $104.94M GLBE : $467.05M
EBITDA (TTM) ZVRA : $149.15M GLBE : $146.46M

Return for Risk

ZVRA vs. GLBE — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

ZVRA

ZVRA Risk / Return Rank: 34
ZVRA Sharpe Ratio Rank: 34
ZVRA Sortino Ratio Rank: 36
ZVRA Omega Ratio Rank: 37
ZVRA Calmar Ratio Rank: 32
ZVRA Martin Ratio Rank: 31

GLBE

GLBE Risk / Return Rank: 58
GLBE Sharpe Ratio Rank: 59
GLBE Sortino Ratio Rank: 56
GLBE Omega Ratio Rank: 55
GLBE Calmar Ratio Rank: 59
GLBE Martin Ratio Rank: 59

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

ZVRA vs. GLBE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Zevra Therapeutics Inc. (ZVRA) and Global-e Online Ltd. (GLBE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ZVRA	GLBE	Difference
Sharpe ratio: Return per unit of total volatility	-0.22	0.39	-0.61
Sortino ratio: Return per unit of downside risk	0.13	0.90	-0.77
Omega ratio: Gain probability vs. loss probability	1.02	1.11	-0.09
Calmar ratio: Return relative to maximum drawdown	-0.36	0.55	-0.91
Martin ratio: Return relative to average drawdown	-0.65	1.21	-1.86

ZVRA vs. GLBE - Sharpe Ratio Comparison

The current ZVRA Sharpe Ratio is -0.22, which is lower than the GLBE Sharpe Ratio of 0.39. The chart below compares the historical Sharpe Ratios of ZVRA and GLBE, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ZVRA vs. GLBE - Drawdown Comparison

The maximum ZVRA drawdown since its inception was -99.27%, which is greater than GLBE's maximum drawdown of -79.10%. Use the drawdown chart below to compare losses from any high point for ZVRA and GLBE.

Drawdown Indicators

	ZVRA	GLBE	Difference
Max Drawdown Largest peak-to-trough decline	-99.27%	-79.10%	-20.17%
Max Drawdown (1Y) Largest decline over 1 year	-40.40%	-33.78%	-6.62%
Max Drawdown (3Y) Largest decline over 3 years	-43.47%	-56.17%	+12.70%
Max Drawdown (5Y) Largest decline over 5 years	-60.97%	-79.10%	+18.13%
Max Drawdown (10Y) Largest decline over 10 years	-97.85%	—	—
Current Drawdown Current decline from peak	-97.48%	-51.88%	-45.60%
Average Drawdown Average peak-to-trough decline	-86.53%	-52.37%	-34.16%
Ulcer Index Depth and duration of drawdowns from previous peaks	22.22%	15.42%	+6.80%

Volatility

ZVRA vs. GLBE - Volatility Comparison

Zevra Therapeutics Inc. (ZVRA) has a higher volatility of 29.44% compared to Global-e Online Ltd. (GLBE) at 12.17%. This indicates that ZVRA's price experiences larger fluctuations and is considered to be riskier than GLBE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ZVRA	GLBE	Difference
Volatility (1M) Calculated over the trailing 1-month period	29.44%	12.17%	+17.27%
Volatility (6M) Calculated over the trailing 6-month period	49.17%	37.76%	+11.41%
Volatility (1Y) Calculated over the trailing 1-year period	65.35%	48.48%	+16.87%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	61.11%	67.18%	-6.07%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	81.05%	67.66%	+13.39%

Dividends

ZVRA vs. GLBE - Dividend Comparison

Neither ZVRA nor GLBE has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ZVRA and GLBE in my portfolio?

ZVRA and GLBE have a correlation of 0.11, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ZVRA or GLBE?

ZVRA has higher volatility (29.44%) compared to GLBE (12.17%). In terms of maximum drawdown, ZVRA dropped -99.27% vs GLBE's -79.10%.

Which has better risk-adjusted returns?

GLBE currently has the higher Sharpe Ratio (0.39 vs -0.22), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.