XGEN.DE vs. SPYH.DE
XGEN.DE (Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C) and SPYH.DE (SPDR MSCI Europe Health Care UCITS ETF) are both Health & Biotech Equities funds - XGEN.DE tracks the MSCI ACWI IMI Genomic Innovation Select ESG Screened 100 while SPYH.DE tracks the MSCI Europe Health Care 20/35 Capped. Both are passively managed. Over the past 3 years, XGEN.DE returned 1.39%/yr vs 2.85%/yr for SPYH.DE. A 0.52 correlation means they provide meaningful diversification when combined. XGEN.DE charges 0.30%/yr vs 0.18%/yr for SPYH.DE.
Performance
XGEN.DE vs. SPYH.DE - Performance Comparison
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Returns By Period
In the year-to-date period, XGEN.DE achieves a -1.40% return, which is significantly higher than SPYH.DE's -1.97% return.
XGEN.DE
- 1D
- 3.92%
- 1M
- 5.33%
- YTD
- -1.40%
- 6M
- -3.45%
- 1Y
- 22.88%
- 3Y*
- 1.39%
- 5Y*
- —
- 10Y*
- —
SPYH.DE
- 1D
- 3.34%
- 1M
- 0.41%
- YTD
- -1.97%
- 6M
- -0.47%
- 1Y
- 6.02%
- 3Y*
- 2.85%
- 5Y*
- 5.81%
- 10Y*
- 6.16%
XGEN.DE vs. SPYH.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
XGEN.DE Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C | -1.40% | 7.38% | 2.95% | -5.84% | -9.98% |
SPYH.DE SPDR MSCI Europe Health Care UCITS ETF | -1.97% | 7.82% | 3.98% | 7.88% | -5.48% |
Correlation
The correlation between XGEN.DE and SPYH.DE is 0.64, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.64 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.53 |
Correlation (All Time) Calculated using the full available price history since Jul 20, 2022 | 0.52 |
The correlation between XGEN.DE and SPYH.DE shifts across timeframes, from 0.52 (all time) to 0.64 (1 year), reflecting how their relationship changes across market environments.
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Return for Risk
XGEN.DE vs. SPYH.DE — Risk / Return Rank
XGEN.DE
SPYH.DE
XGEN.DE vs. SPYH.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C (XGEN.DE) and SPDR MSCI Europe Health Care UCITS ETF (SPYH.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| XGEN.DE | SPYH.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.86 | ||
| Sortino ratioReturn per unit of downside risk | +1.18 | ||
| Omega ratioGain probability vs. loss probability | 1.21 | 1.08 | +0.13 |
| Calmar ratioReturn relative to maximum drawdown | 1.49 | 0.50 | +0.99 |
| Martin ratioReturn relative to average drawdown | 3.61 | 1.10 | +2.51 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| XGEN.DE | SPYH.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.23 | 0.37 | +0.86 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | — | 0.36 | — |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | — | 0.39 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.11 | 0.43 | -0.53 |
Drawdowns
XGEN.DE vs. SPYH.DE - Drawdown Comparison
The maximum XGEN.DE drawdown since its inception was -37.58%, which is greater than SPYH.DE's maximum drawdown of -26.62%. Use the drawdown chart below to compare losses from any high point for XGEN.DE and SPYH.DE.
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Drawdown Indicators
| XGEN.DE | SPYH.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -37.58% | -26.62% | -10.96% |
Max Drawdown (1Y)Largest decline over 1 year | -14.99% | -12.58% | -2.41% |
Max Drawdown (3Y)Largest decline over 3 years | -28.21% | -26.62% | -1.59% |
Max Drawdown (5Y)Largest decline over 5 years | — | -26.62% | — |
Max Drawdown (10Y)Largest decline over 10 years | — | -26.62% | — |
Current DrawdownCurrent decline from peak | -14.86% | -10.72% | -4.14% |
Average DrawdownAverage peak-to-trough decline | -19.44% | -8.61% | -10.83% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.19% | 5.73% | +0.46% |
Volatility
XGEN.DE vs. SPYH.DE - Volatility Comparison
Xtrackers MSCI Genomic Healthcare Innovation UCITS ETF 1C (XGEN.DE) has a higher volatility of 6.48% compared to SPDR MSCI Europe Health Care UCITS ETF (SPYH.DE) at 6.01%. This indicates that XGEN.DE's price experiences larger fluctuations and is considered to be riskier than SPYH.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| XGEN.DE | SPYH.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 6.48% | 6.01% | +0.47% |
Volatility (6M)Calculated over the trailing 6-month period | 13.73% | 12.04% | +1.69% |
Volatility (1Y)Calculated over the trailing 1-year period | 18.19% | 17.05% | +1.14% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 18.66% | 15.76% | +2.90% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 18.66% | 15.82% | +2.84% |
XGEN.DE vs. SPYH.DE - Expense Ratio Comparison
XGEN.DE has a 0.30% expense ratio, which is higher than SPYH.DE's 0.18% expense ratio.
Dividends
XGEN.DE vs. SPYH.DE - Dividend Comparison
Neither XGEN.DE nor SPYH.DE has paid dividends to shareholders.
Frequently Asked Questions
XGEN.DE and SPYH.DE have a correlation of 0.64, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, SPYH.DE is cheaper at 0.18% per year. The better choice depends on whether you care most about return, fees, risk, or income.
SPYH.DE is cheaper with a 0.18% expense ratio, compared with 0.30% for XGEN.DE.
XGEN.DE tracks MSCI ACWI IMI Genomic Innovation Select ESG Screened 100, while SPYH.DE tracks MSCI Europe Health Care 20/35 Capped. They also come from different issuers: Xtrackers and State Street. Their fees differ too: 0.30% for XGEN.DE and 0.18% for SPYH.DE.
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