WRNA.DE vs. CBUF.DE
WRNA.DE (WisdomTree BioRevolution UCITS ETF USD Acc) and CBUF.DE (iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist) are both Health & Biotech Equities funds - WRNA.DE tracks the WisdomTree BioRevolution ESG Screened while CBUF.DE tracks the MSCI World Health Care ESG Reduced Carbon Select 20 35 Capped. Both are passively managed. Over the past 3 years, WRNA.DE returned 0.92%/yr vs 0.62%/yr for CBUF.DE. A 0.59 correlation means they provide meaningful diversification when combined. WRNA.DE charges 0.45%/yr vs 0.18%/yr for CBUF.DE.
Performance
WRNA.DE vs. CBUF.DE - Performance Comparison
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Returns By Period
In the year-to-date period, WRNA.DE achieves a 10.48% return, which is significantly higher than CBUF.DE's -2.22% return.
WRNA.DE
- 1D
- 4.08%
- 1M
- 4.18%
- YTD
- 10.48%
- 6M
- 10.41%
- 1Y
- 48.70%
- 3Y*
- 0.92%
- 5Y*
- —
- 10Y*
- —
CBUF.DE
- 1D
- 2.74%
- 1M
- 3.91%
- YTD
- -2.22%
- 6M
- -1.50%
- 1Y
- 7.40%
- 3Y*
- 0.62%
- 5Y*
- 4.66%
- 10Y*
- —
WRNA.DE vs. CBUF.DE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
WRNA.DE WisdomTree BioRevolution UCITS ETF USD Acc | 10.48% | 9.13% | -10.92% | -3.37% | -22.01% | -0.98% |
CBUF.DE iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist | -2.22% | 2.56% | 0.75% | 0.33% | 2.09% | 4.20% |
Correlation
The correlation between WRNA.DE and CBUF.DE is 0.55, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.55 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.52 |
Correlation (All Time) Calculated using the full available price history since Dec 10, 2021 | 0.59 |
The correlation between WRNA.DE and CBUF.DE has been stable across timeframes, ranging from 0.52 to 0.59 - a consistent structural relationship.
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Return for Risk
WRNA.DE vs. CBUF.DE — Risk / Return Rank
WRNA.DE
CBUF.DE
WRNA.DE vs. CBUF.DE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution UCITS ETF USD Acc (WRNA.DE) and iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist (CBUF.DE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| WRNA.DE | CBUF.DE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.22 | ||
| Sortino ratioReturn per unit of downside risk | +1.59 | ||
| Omega ratioGain probability vs. loss probability | 1.30 | 1.10 | +0.20 |
| Calmar ratioReturn relative to maximum drawdown | 3.61 | 0.68 | +2.93 |
| Martin ratioReturn relative to average drawdown | 9.63 | 1.56 | +8.07 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| WRNA.DE | CBUF.DE | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.75 | 0.53 | +1.22 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | — | 0.34 | — |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.20 | 0.44 | -0.64 |
Drawdowns
WRNA.DE vs. CBUF.DE - Drawdown Comparison
The maximum WRNA.DE drawdown since its inception was -52.35%, which is greater than CBUF.DE's maximum drawdown of -25.94%. Use the drawdown chart below to compare losses from any high point for WRNA.DE and CBUF.DE.
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Drawdown Indicators
| WRNA.DE | CBUF.DE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -52.35% | -25.94% | -26.41% |
Max Drawdown (1Y)Largest decline over 1 year | -13.42% | -10.87% | -2.55% |
Max Drawdown (3Y)Largest decline over 3 years | -40.06% | -21.76% | -18.30% |
Max Drawdown (5Y)Largest decline over 5 years | — | -21.76% | — |
Current DrawdownCurrent decline from peak | -20.73% | -9.66% | -11.07% |
Average DrawdownAverage peak-to-trough decline | -27.26% | -5.65% | -21.61% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 5.04% | 4.74% | +0.30% |
Volatility
WRNA.DE vs. CBUF.DE - Volatility Comparison
WisdomTree BioRevolution UCITS ETF USD Acc (WRNA.DE) has a higher volatility of 6.73% compared to iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist (CBUF.DE) at 4.98%. This indicates that WRNA.DE's price experiences larger fluctuations and is considered to be riskier than CBUF.DE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| WRNA.DE | CBUF.DE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 6.73% | 4.98% | +1.75% |
Volatility (6M)Calculated over the trailing 6-month period | 17.21% | 9.70% | +7.51% |
Volatility (1Y)Calculated over the trailing 1-year period | 27.70% | 13.98% | +13.72% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 24.22% | 13.60% | +10.62% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 24.22% | 15.36% | +8.86% |
WRNA.DE vs. CBUF.DE - Expense Ratio Comparison
WRNA.DE has a 0.45% expense ratio, which is higher than CBUF.DE's 0.18% expense ratio.
Dividends
WRNA.DE vs. CBUF.DE - Dividend Comparison
WRNA.DE has not paid dividends to shareholders, while CBUF.DE's dividend yield for the trailing twelve months is around 1.08%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
CBUF.DE iShares MSCI World Health Care Sector ESG UCITS ETF USD Dist | 1.08% | 1.06% | 1.02% | 1.16% | 1.09% | 1.05% | 1.27% | 0.10% |
WRNA.DE WisdomTree BioRevolution UCITS ETF USD Acc | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Frequently Asked Questions
WRNA.DE and CBUF.DE have a correlation of 0.55, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
On fees, CBUF.DE is cheaper at 0.18% per year. The better choice depends on whether you care most about return, fees, risk, or income.
CBUF.DE is cheaper with a 0.18% expense ratio, compared with 0.45% for WRNA.DE.
WRNA.DE tracks WisdomTree BioRevolution ESG Screened, while CBUF.DE tracks MSCI World Health Care ESG Reduced Carbon Select 20 35 Capped. They also come from different issuers: WisdomTree and iShares. Their fees differ too: 0.45% for WRNA.DE and 0.18% for CBUF.DE.
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