WDNA vs. BTEC

Last updated Jun 5, 2026

WDNA (WisdomTree BioRevolution Fund) and BTEC (Principal Healthcare Innovators Index ETF) are both Health & Biotech Equities funds - WDNA tracks the WisdomTree BioRevolution Index while BTEC tracks the NASDAQ U.S. Health Care Innovators Index. Both are passively managed. WDNA charges 0.45%/yr vs 0.42%/yr for BTEC.

Performance

WDNA vs. BTEC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in WisdomTree BioRevolution Fund (WDNA) and Principal Healthcare Innovators Index ETF (BTEC). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

WDNA

• 1D: 2.94%
• 1M: 2.56%
• YTD: 8.96%
• 6M: 10.44%
• 1Y: 50.50%
• 3Y*: 3.54%
• 5Y*: -4.78%
• 10Y*: —

BTEC

• 1D: 0.00%
• 1M: 0.00%
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

WDNA vs. BTEC - Yearly Performance Comparison

	2026 (YTD)
WDNA WisdomTree BioRevolution Fund	2.90%
BTEC Principal Healthcare Innovators Index ETF	0.00%

WDNA vs. BTEC - Sectors Allocation Comparison

Sectors	WDNA	BTEC
Healthcare	85.0%	99.4%
Basic Materials	6.5%	-
Consumer Defensive	3.0%	-
Energy	1.1%	-
Communication Services	-	-
Consumer Cyclical	-	-
Financial Services	-	-
Industrials	-	0.6%
Real Estate	-	-
Technology	-	-
Utilities	-	-

Return for Risk

WDNA vs. BTEC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

WDNA

WDNA Risk / Return Rank: 63
WDNA Sharpe Ratio Rank: 59
WDNA Sortino Ratio Rank: 62
WDNA Omega Ratio Rank: 53
WDNA Calmar Ratio Rank: 83
WDNA Martin Ratio Rank: 57

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

WDNA vs. BTEC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for WisdomTree BioRevolution Fund (WDNA) and Principal Healthcare Innovators Index ETF (BTEC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	WDNA	BTEC	Difference
Sharpe ratio: Return per unit of total volatility	1.98	—	—
Sortino ratio: Return per unit of downside risk	2.85	—	—
Omega ratio: Gain probability vs. loss probability	1.32	—	—
Calmar ratio: Return relative to maximum drawdown	4.34	—	—
Martin ratio: Return relative to average drawdown	9.85	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	WDNA	BTEC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	1.98	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.19	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.19	—	—

Drawdowns

WDNA vs. BTEC - Drawdown Comparison

The maximum WDNA drawdown since its inception was -58.87%, which is greater than BTEC's maximum drawdown of 0.00%. Use the drawdown chart below to compare losses from any high point for WDNA and BTEC.

Drawdown Indicators

	WDNA	BTEC	Difference
Max Drawdown Largest peak-to-trough decline	-58.87%	0.00%	-58.87%
Max Drawdown (1Y) Largest decline over 1 year	-11.70%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-38.25%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-58.87%	—	—
Current Drawdown Current decline from peak	-29.86%	0.00%	-29.86%
Average Drawdown Average peak-to-trough decline	-35.64%	0.00%	-35.64%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.14%	—	—

Volatility

Volatility by Period

	WDNA	BTEC	Difference
Volatility (1M) Calculated over the trailing 1-month period	7.35%	—	—
Volatility (6M) Calculated over the trailing 6-month period	16.59%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	25.66%	0.00%	+25.66%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.08%	0.00%	+25.08%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	25.07%	0.00%	+25.07%

WDNA vs. BTEC - Expense Ratio Comparison

WDNA has a 0.45% expense ratio, which is higher than BTEC's 0.42% expense ratio.

Dividends

WDNA vs. BTEC - Dividend Comparison

WDNA's dividend yield for the trailing twelve months is around 4.19%, while BTEC has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021
BTEC Principal Healthcare Innovators Index ETF	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
WDNA WisdomTree BioRevolution Fund	4.19%	4.57%	0.75%	0.80%	0.38%	0.10%

Frequently Asked Questions

Which ETF is better, WDNA or BTEC?

On fees, BTEC is cheaper at 0.42% per year. The better choice depends on whether you care most about return, fees, risk, or income.

Which ETF is cheaper, WDNA or BTEC?

BTEC is cheaper with a 0.42% expense ratio, compared with 0.45% for WDNA.

Which ETF pays a higher dividend yield, WDNA or BTEC?

WDNA has the higher dividend yield at 4.19%, compared with 0.00% for BTEC.

What is the main difference between WDNA and BTEC?

WDNA tracks WisdomTree BioRevolution Index, while BTEC tracks NASDAQ U.S. Health Care Innovators Index. They also come from different issuers: WisdomTree and Principal. Their fees differ too: 0.45% for WDNA and 0.42% for BTEC.