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VXRT vs. CYCN
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

VXRT vs. CYCN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vaxart, Inc. (VXRT) and Cyclerion Therapeutics, Inc. (CYCN). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, VXRT achieves a 55.89% return, which is significantly lower than CYCN's 170.87% return.


VXRT

1D
2.46%
1M
-15.63%
6M
-6.86%
YTD
55.89%
1Y
51.77%
3Y*
-11.52%
5Y*
-40.42%
10Y*
ALL TIME*
-27.88%

CYCN

1D
-1.71%
1M
0.29%
6M
152.94%
YTD
170.87%
1Y
32.63%
3Y*
1.39%
5Y*
-43.20%
10Y*
ALL TIME*
-47.56%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$64.32K$78.06K$115.62K
$154.47K$165.76K$219.97K

VXRT vs. CYCN - Yearly Performance Comparison


2026 (YTD)2025202420232022202120202019
VXRT
Vaxart, Inc.
55.89%-47.68%15.59%-40.39%-84.67%9.81%1,529.10%-82.82%
CYCN
Cyclerion Therapeutics, Inc.
170.87%-60.56%-3.88%-74.47%-61.85%-43.79%12.50%-86.07%

Correlation

The correlation between VXRT and CYCN is 0.06, meaning there was essentially no consistent relationship between their historical price movements. Each responded to its own set of market drivers.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.06

Correlation (3Y)
Balances recent behavior with more history.

0.03

Correlation (5Y)
Shows whether the relationship held over a longer period.

0.09

Correlation (All Time)
Calculated using the full available price history since Apr 2, 2019

0.08

Fundamentals

Market Cap

VXRT:

$130.70M

CYCN:

$14.90M

EPS

VXRT:

$0.16

CYCN:

-$0.59

PS Ratio

VXRT:

0.49

CYCN:

6.13

PB Ratio

VXRT:

1.39

CYCN:

2.13

Total Revenue (TTM)

VXRT:

$255.61M

CYCN:

$1.99M

Gross Profit (TTM)

VXRT:

$193.63M

CYCN:

$1.99M

EBITDA (TTM)

VXRT:

$45.63M

CYCN:

-$6.70M

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Vaxart, Inc.

Cyclerion Therapeutics, Inc.

Return for Risk

VXRT vs. CYCN — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

VXRT
VXRT Risk / Return Rank: 6767
Overall Rank
VXRT Sharpe Ratio Rank: 6363
Sharpe Ratio Rank
VXRT Sortino Ratio Rank: 6969
Sortino Ratio Rank
VXRT Omega Ratio Rank: 7070
Omega Ratio Rank
VXRT Calmar Ratio Rank: 6767
Calmar Ratio Rank
VXRT Martin Ratio Rank: 6868
Martin Ratio Rank

CYCN
CYCN Risk / Return Rank: 7070
Overall Rank
CYCN Sharpe Ratio Rank: 4848
Sharpe Ratio Rank
CYCN Sortino Ratio Rank: 9696
Sortino Ratio Rank
CYCN Omega Ratio Rank: 9595
Omega Ratio Rank
CYCN Calmar Ratio Rank: 5656
Calmar Ratio Rank
CYCN Martin Ratio Rank: 5353
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

VXRT vs. CYCN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Vaxart, Inc. (VXRT) and Cyclerion Therapeutics, Inc. (CYCN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


VXRTCYCNDifference
Sharpe ratioReturn per unit of total volatility

+0.43

Sortino ratioReturn per unit of downside risk

-2.12

Omega ratioGain probability vs. loss probability

1.19

1.48

-0.29

Calmar ratioReturn relative to maximum drawdown

1.06

0.45

+0.61

Martin ratioReturn relative to average drawdown

2.52

0.64

+1.88

VXRT vs. CYCN - Sharpe Ratio Comparison

The current VXRT Sharpe Ratio is 0.53, which is higher than the CYCN Sharpe Ratio of 0.09. The chart below compares the historical Sharpe Ratios of VXRT and CYCN, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

VXRT vs. CYCN - Drawdown Comparison

The maximum VXRT drawdown since its inception was -98.71%, roughly equal to the maximum CYCN drawdown of -99.72%. Use the drawdown chart below to compare losses from any high point for VXRT and CYCN.


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Drawdown Indicators


VXRTCYCNDifference

Max Drawdown

Largest peak-to-trough decline

-98.71%

-99.72%

+1.01%

Max Drawdown (1Y)

Largest decline over 1 year

-43.74%

-66.77%

+23.03%

Max Drawdown (3Y)

Largest decline over 3 years

-78.72%

-82.99%

+4.27%

Max Drawdown (5Y)

Largest decline over 5 years

-96.94%

-98.45%

+1.51%

Current Drawdown

Current decline from peak

-97.69%

-99.12%

+1.43%

Average Drawdown

Average peak-to-trough decline

-83.17%

-88.61%

+5.44%

Ulcer Index

Depth and duration of drawdowns from previous peaks

18.26%

46.37%

-28.11%

Volatility

VXRT vs. CYCN - Volatility Comparison

Vaxart, Inc. (VXRT) has a higher volatility of 22.10% compared to Cyclerion Therapeutics, Inc. (CYCN) at 14.24%. This indicates that VXRT's price experiences larger fluctuations and is considered to be riskier than CYCN based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


VXRTCYCNDifference

Volatility (1M)

Calculated over the trailing 1-month period

22.10%

14.24%

+7.86%

Volatility (6M)

Calculated over the trailing 6-month period

50.47%

154.47%

-104.00%

Volatility (1Y)

Calculated over the trailing 1-year period

87.77%

326.92%

-239.15%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

92.48%

229.41%

-136.93%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

127.94%

202.24%

-74.30%

Dividends

VXRT vs. CYCN - Dividend Comparison

Neither VXRT nor CYCN has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

VXRT vs. CYCN - Financials Comparison

This section allows you to compare key financial metrics between Vaxart, Inc. and Cyclerion Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

Frequently Asked Questions


VXRT and CYCN have a correlation of 0.06, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

VXRT has higher volatility (22.10%) compared to CYCN (14.24%). In terms of maximum drawdown, VXRT dropped -98.71% vs CYCN's -99.72%.

VXRT currently has the higher Sharpe Ratio (0.53 vs 0.09), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for VXRT and CYCN

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