TNGX vs. NA.TO

Last updated Jun 13, 2026

TNGX (Tango Therapeutics, Inc.) and NA.TO (National Bank of Canada) are both stocks. TNGX operates in Biotechnology (Healthcare), while NA.TO operates in Banks - Diversified (Financial Services). Over the past 5 years, TNGX returned 22.99%/yr vs 19.01%/yr for NA.TO. At a 0.13 correlation, their price movements are largely independent.

Performance

TNGX vs. NA.TO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Tango Therapeutics, Inc. (TNGX) and National Bank of Canada (NA.TO). The values are adjusted to include any dividend payments, if applicable.

Different Trading Currencies

TNGX is traded in USD, while NA.TO is traded in CAD. To make them comparable, the NA.TO values have been converted to USD using the latest available exchange rates.

Returns By Period

In the year-to-date period, TNGX achieves a 249.21% return, which is significantly higher than NA.TO's 19.91% return.

TNGX

• 1D: 3.76%
• 1M: 21.29%
• YTD: 249.21%
• 6M: 230.91%
• 1Y: 512.67%
• 3Y*: 104.27%
• 5Y*: 22.99%
• 10Y*: —

NA.TO

• 1D: 0.39%
• 1M: 0.46%
• YTD: 19.91%
• 6M: 21.47%
• 1Y: 56.62%
• 3Y*: 31.79%
• 5Y*: 19.01%
• 10Y*: 20.44%

*Multi-year figures are annualized to reflect compound growth (CAGR)

TNGX vs. NA.TO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
TNGX Tango Therapeutics, Inc.	249.21%	186.73%	-68.79%	36.55%	-33.73%	-4.37%	15.79%
NA.TO National Bank of Canada	19.84%	42.66%	24.14%	18.35%	-7.33%	39.09%	3.06%

Correlation

The correlation between TNGX and NA.TO is 0.10, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.10
Correlation (3Y) Calculated over the trailing 3-year period	0.09
Correlation (5Y) Calculated over the trailing 5-year period	0.15
Correlation (All Time) Calculated using the full available price history since Sep 3, 2020	0.13

Fundamentals

Market Cap TNGX : $4.44B NA.TO : CA$82.13B
EPS TNGX : -$0.89 NA.TO : CA$11.69
PS Ratio TNGX : 65.32 NA.TO : 3.03
PB Ratio TNGX : 11.35 NA.TO : 2.65
Total Revenue (TTM) TNGX : $56.99M NA.TO : CA$27.33B
Gross Profit (TTM) TNGX : $55.33M NA.TO : CA$14.01B
EBITDA (TTM) TNGX : -$111.92M NA.TO : CA$6.37B

Return for Risk

TNGX vs. NA.TO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TNGX

TNGX Risk / Return Rank: 98
TNGX Sharpe Ratio Rank: 99
TNGX Sortino Ratio Rank: 98
TNGX Omega Ratio Rank: 96
TNGX Calmar Ratio Rank: 99
TNGX Martin Ratio Rank: 99

NA.TO

NA.TO Risk / Return Rank: 97
NA.TO Sharpe Ratio Rank: 98
NA.TO Sortino Ratio Rank: 98
NA.TO Omega Ratio Rank: 98
NA.TO Calmar Ratio Rank: 95
NA.TO Martin Ratio Rank: 97

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TNGX vs. NA.TO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Tango Therapeutics, Inc. (TNGX) and National Bank of Canada (NA.TO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	TNGX	NA.TO	Difference
Sharpe ratio: Return per unit of total volatility	5.18	3.39	+1.80
Sortino ratio: Return per unit of downside risk	4.89	4.55	+0.34
Omega ratio: Gain probability vs. loss probability	1.60	1.61	-0.01
Calmar ratio: Return relative to maximum drawdown	17.69	5.84	+11.84
Martin ratio: Return relative to average drawdown	46.00	19.63	+26.38

TNGX vs. NA.TO - Sharpe Ratio Comparison

The current TNGX Sharpe Ratio is 5.18, which is higher than the NA.TO Sharpe Ratio of 3.39. The chart below compares the historical Sharpe Ratios of TNGX and NA.TO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

TNGX vs. NA.TO - Drawdown Comparison

The maximum TNGX drawdown since its inception was -93.64%, which is greater than NA.TO's maximum drawdown of -60.25%. Use the drawdown chart below to compare losses from any high point for TNGX and NA.TO.

Drawdown Indicators

	TNGX	NA.TO	Difference
Max Drawdown Largest peak-to-trough decline	-93.64%	-60.25%	-33.39%
Max Drawdown (1Y) Largest decline over 1 year	-29.24%	-9.74%	-19.50%
Max Drawdown (3Y) Largest decline over 3 years	-91.46%	-23.63%	-67.83%
Max Drawdown (5Y) Largest decline over 5 years	-93.64%	-25.64%	-68.00%
Max Drawdown (10Y) Largest decline over 10 years	—	-52.59%	—
Current Drawdown Current decline from peak	-1.96%	-2.92%	+0.96%
Average Drawdown Average peak-to-trough decline	-47.98%	-9.09%	-38.89%
Ulcer Index Depth and duration of drawdowns from previous peaks	11.24%	2.89%	+8.35%

Volatility

TNGX vs. NA.TO - Volatility Comparison

Tango Therapeutics, Inc. (TNGX) has a higher volatility of 52.40% compared to National Bank of Canada (NA.TO) at 5.98%. This indicates that TNGX's price experiences larger fluctuations and is considered to be riskier than NA.TO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TNGX	NA.TO	Difference
Volatility (1M) Calculated over the trailing 1-month period	52.40%	5.98%	+46.42%
Volatility (6M) Calculated over the trailing 6-month period	77.75%	14.12%	+63.63%
Volatility (1Y) Calculated over the trailing 1-year period	99.90%	16.79%	+83.11%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	101.94%	18.83%	+83.11%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	96.02%	22.22%	+73.80%

Dividends

TNGX vs. NA.TO - Dividend Comparison

TNGX has not paid dividends to shareholders, while NA.TO's dividend yield for the trailing twelve months is around 2.31%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
NA.TO National Bank of Canada	2.31%	2.75%	3.36%	4.03%	4.03%	3.11%	3.96%	3.77%	4.44%	3.70%	4.03%	5.16%
TNGX Tango Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

Frequently Asked Questions

Can I hold both TNGX and NA.TO in my portfolio?

TNGX and NA.TO have a correlation of 0.10, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.