TGTX vs. ISSC
TGTX (TG Therapeutics, Inc.) and ISSC (Innovative Solutions and Support, Inc.) are both stocks. TGTX operates in Biotechnology (Healthcare), while ISSC operates in Aerospace & Defense (Industrials). Over the past 10 years, TGTX returned 21.61%/yr vs 21.80%/yr for ISSC. At a 0.09 correlation, their price movements are largely independent.
Performance
TGTX vs. ISSC - Performance Comparison
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Returns By Period
In the year-to-date period, TGTX achieves a 66.12% return, which is significantly higher than ISSC's -2.43% return. Both investments have delivered pretty close results over the past 10 years, with TGTX having a 21.61% annualized return and ISSC not far ahead at 21.80%.
TGTX
- 1D
- 3.06%
- 1M
- 16.11%
- YTD
- 66.12%
- 6M
- 57.96%
- 1Y
- 32.51%
- 3Y*
- 21.69%
- 5Y*
- 5.57%
- 10Y*
- 21.61%
ISSC
- 1D
- -4.59%
- 1M
- -10.25%
- YTD
- -2.43%
- 6M
- 65.59%
- 1Y
- 50.12%
- 3Y*
- 38.47%
- 5Y*
- 24.62%
- 10Y*
- 21.80%
TGTX vs. ISSC - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
TGTX TG Therapeutics, Inc. | 66.12% | -0.96% | 76.23% | 44.38% | -37.74% | -63.48% | 368.65% | 170.73% | -50.00% | 76.34% |
ISSC Innovative Solutions and Support, Inc. | -2.43% | 121.78% | 0.12% | 3.77% | 25.32% | 0.61% | 29.83% | 158.41% | -23.13% | -11.71% |
Correlation
The correlation between TGTX and ISSC is 0.22, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.22 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.10 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.11 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.10 |
Correlation (All Time) Calculated using the full available price history since May 3, 2010 | 0.09 |
The correlation between TGTX and ISSC shifts across timeframes, from 0.09 (all time) to 0.22 (1 year), reflecting how their relationship changes across market environments.
Fundamentals
TGTX:
$7.93B
ISSC:
$338.23M
TGTX:
$2.87
ISSC:
$0.94
TGTX:
17.23
ISSC:
19.62
TGTX:
0.03
ISSC:
0.50
TGTX:
11.37
ISSC:
3.69
TGTX:
13.59
ISSC:
4.69
TGTX:
$700.35M
ISSC:
$90.56M
TGTX:
$581.54M
ISSC:
$44.22M
TGTX:
$156.88M
ISSC:
$26.70M
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Return for Risk
TGTX vs. ISSC — Risk / Return Rank
TGTX
ISSC
TGTX vs. ISSC - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for TG Therapeutics, Inc. (TGTX) and Innovative Solutions and Support, Inc. (ISSC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| TGTX | ISSC | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +0.09 | ||
| Sortino ratioReturn per unit of downside risk | -0.08 | ||
| Omega ratioGain probability vs. loss probability | 1.16 | 1.18 | -0.02 |
| Calmar ratioReturn relative to maximum drawdown | 1.00 | 0.87 | +0.13 |
| Martin ratioReturn relative to average drawdown | 1.81 | 1.59 | +0.22 |
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Drawdowns
TGTX vs. ISSC - Drawdown Comparison
The maximum TGTX drawdown since its inception was -99.52%, which is greater than ISSC's maximum drawdown of -89.03%. Use the drawdown chart below to compare losses from any high point for TGTX and ISSC.
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Drawdown Indicators
| TGTX | ISSC | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.52% | -89.03% | -10.49% |
Max Drawdown (1Y)Largest decline over 1 year | -32.66% | -57.83% | +25.17% |
Max Drawdown (3Y)Largest decline over 3 years | -75.42% | -57.83% | -17.59% |
Max Drawdown (5Y)Largest decline over 5 years | -90.75% | -57.83% | -32.92% |
Max Drawdown (10Y)Largest decline over 10 years | -93.19% | -62.41% | -30.78% |
Current DrawdownCurrent decline from peak | -78.79% | -39.53% | -39.26% |
Average DrawdownAverage peak-to-trough decline | -91.43% | -50.58% | -40.85% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 18.04% | 31.63% | -13.59% |
Volatility
TGTX vs. ISSC - Volatility Comparison
The current volatility for TG Therapeutics, Inc. (TGTX) is 15.65%, while Innovative Solutions and Support, Inc. (ISSC) has a volatility of 25.92%. This indicates that TGTX experiences smaller price fluctuations and is considered to be less risky than ISSC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| TGTX | ISSC | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 15.65% | 25.92% | -10.27% |
Volatility (6M)Calculated over the trailing 6-month period | 34.28% | 65.82% | -31.54% |
Volatility (1Y)Calculated over the trailing 1-year period | 47.22% | 83.28% | -36.06% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 87.77% | 59.11% | +28.66% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 86.88% | 57.12% | +29.76% |
Dividends
TGTX vs. ISSC - Dividend Comparison
Neither TGTX nor ISSC has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
ISSC Innovative Solutions and Support, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.01% | 0.00% | 17.64% |
TGTX TG Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Financials
TGTX vs. ISSC - Financials Comparison
This section allows you to compare key financial metrics between TG Therapeutics, Inc. and Innovative Solutions and Support, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
TGTX vs. ISSC - Profitability Comparison
TGTX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, TG Therapeutics, Inc. reported a gross profit of 171.41M and revenue of 204.92M. Therefore, the gross margin over that period was 83.7%.
ISSC - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Innovative Solutions and Support, Inc. reported a gross profit of 11.43M and revenue of 22.37M. Therefore, the gross margin over that period was 51.1%.
TGTX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, TG Therapeutics, Inc. reported an operating income of 34.80M and revenue of 204.92M, resulting in an operating margin of 17.0%.
ISSC - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Innovative Solutions and Support, Inc. reported an operating income of 4.94M and revenue of 22.37M, resulting in an operating margin of 22.1%.
TGTX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, TG Therapeutics, Inc. reported a net income of 19.78M and revenue of 204.92M, resulting in a net margin of 9.7%.
ISSC - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Innovative Solutions and Support, Inc. reported a net income of 3.43M and revenue of 22.37M, resulting in a net margin of 15.4%.
Frequently Asked Questions
TGTX and ISSC have a correlation of 0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
ISSC has higher volatility (25.92%) compared to TGTX (15.65%). In terms of maximum drawdown, TGTX dropped -99.52% vs ISSC's -89.03%.
TGTX currently has the higher Sharpe Ratio (0.69 vs 0.60), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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